Relationship between Chemical Structure and Antimicrobial Activities of Isothiocyanates from Cruciferous Vegetables against Oral Pathogens

2016 ◽  
Vol 26 (12) ◽  
pp. 2036-2042 ◽  
Author(s):  
Mi-Ok Ko ◽  
Mi-Bo Kim ◽  
Sang-Bin Lim
Keyword(s):  
Chemical Structure ◽  
Antimicrobial Activities ◽  
Cruciferous Vegetables ◽  
Oral Pathogens

Study of Physico-chemical Characteristics and Pharmacological Effects of 1-Ethyl-Salicyldene-bis-Ethylene-Diamine and Its Complex with Mn(II)

2019 ◽  
Vol 70 (7) ◽  
pp. 2534-2537
Author(s):  
Gladiola Tantaru ◽  
Mihai Apostu ◽  
Antonia Poiata ◽  
Mihai Nichifor ◽  
Nela Bibire ◽  
...  
Keyword(s):  
Schiff Base ◽  
Chemical Structure ◽  
Antimicrobial Activities ◽  
Ethylene Diamine ◽  
Chemical Characteristics ◽  
Gram Negative Bacteria ◽  
Pharmacological Effects ◽  
Physico Chemical ◽  
Anti Inflammatory ◽  
Inflammatory Effect

The paper presents the synthesis of a new complex combination of a Bis-Schiff base with Mn(II) ions with great potential for antimicrobial and anti-inflammatory activity. A new complex of the Salen-type ligand, 1-ethyl-salicylidene-bis-ethylene diamine was synthetized using Mn(II) ions. The chemical structure was confirmed through 1H-NMR and IR spectroscopy. The antimicrobial activities of the Bis-Schiff base and its complex were tested in comparison with Ampicillin, Chloramphenicol, Tetracycline, Ofloxacin and Nystatin. Those compounds were found to be active against Gram-positive or Gram-negative bacteria, and had an anti-inflammatory effect comparable to that of Indomethacin.

Enhanced antimicrobial activities of silver-nanoparticle-decorated reduced graphene nanocomposites against oral pathogens

2017 ◽  
Vol 71 ◽  
pp. 10-16 ◽  
Author(s):  
Jian-min Peng ◽  
Jia-cheng Lin ◽  
Zhuo-yu Chen ◽  
Meng-chao Wei ◽  
Yuan-xiang Fu ◽  
...  
Keyword(s):  
Silver Nanoparticle ◽  
Antimicrobial Activities ◽  
Graphene Nanocomposites ◽  
Reduced Graphene ◽  
Oral Pathogens

scholarly journals Herbal mouthwash formulated with the leaf extract of Jatropha gossypiifolia Linn. (Euphorbiaceae) exhibited in vitro antimicrobial activity against selected oral pathogens

2021 ◽  
Vol 18 (3) ◽  
pp. 207-214
Author(s):  
Abel Olusola Idowu ◽  
Nwamaka Henrietta Igbokwe ◽  
Oreoluwa Ayomide Abiodun ◽  
Chijioke Ofomata
Keyword(s):  
Antimicrobial Activity ◽  
Leaf Extract ◽  
Antimicrobial Activities ◽  
Oral Disease ◽  
Bioactive Metabolites ◽  
Diffusion Method ◽  
Klebsiella Pneumonia ◽  
Root Bark ◽  
Oral Pathogens ◽  
Jatropha Gossypiifolia

Increase in the incidence of oral disease, resistance to antibiotics and adverse effect to synthetic medicines has made search for alternative safe, effective and cheaper treatment options imperative, preferably from plant sources. This study evaluated the antimicrobial profile of ethanol extracts of leaf and root bark of Jatropha gossypiifolia and mouthwash formulation containing the leaf extract. Extraction of plant parts was done by cold maceration with 70% ethanol. The antimicrobial activities of the extracts and the formulated mouthwash were evaluated againstStaphylococcus aureus, Escherichia coli, Klebsiella pneumonia, Bacillus subtilis and Candida albicans using Agar well diffusion method. The minimum inhibitory concentration of the extracts on susceptible organisms was determined according to the Clinical Laboratory Standards Institute protocol. The physicochemical parameters of the formulated mouthwash were assessed using standard methods. J. gossypiifolia leaf and root bark extracts exhibited a concentration dependent antimicrobial activity and MIC ranging from 50 to 260 mg/ml against test organisms. The formulated herbal mouthwash showed effective antimicrobial activity and suitable cosmetics properties. This study indicates that the leaf extracts of J. gossypiifolia possess bioactive metabolites with strong antimicrobial activities and its herbal mouthwash formulation has potential in the treatment of various diseases caused by oral pathogens.

scholarly journals Antimicrobial activities of citronella (Cymbopogon nardus) essential oil against several oral pathogens and its volatile compounds

2020 ◽  
Vol 32 (1) ◽  
pp. 1
Author(s):  
Henny Zaliyana Ahmad Kamal ◽  
Tuan Nadrah Naim Tuan Ismail ◽  
Erry Mochamad Arief ◽  
Kannan Thirumulu Ponnuraj
Keyword(s):  
Essential Oil ◽  
Volatile Compounds ◽  
Inhibitory Activity ◽  
Antimicrobial Activities ◽  
Raw Material ◽  
Gas Chromatography Mass Spectrometry ◽  
Therapeutic Effects ◽  
Cymbopogon Nardus ◽  
Oral Pathogens

Introduction: Cymbopogon nardus is a strong aromatic plant with relevant medicinal properties due to its essential chemical compounds and its potential therapeutic effects. This study was aimed to evaluate the antimicrobial activities of citronella essential oil against several oral pathogens and to identify the volatile compounds. Methods: The essential oil of C. nardus was purchased from Excellent Wisdom Sdn. Bhd., Malaysia. The source of raw material was collected from Malacca, the southern region of Malaysia, and the company made its taxonomic identification. An experimental in-vitro study was conducted on the essential oil processed from C. nardus genus Cymbopogon of Poaceae family. The in-vitro antimicrobial activities of C. nardus essential oil were evaluated against Streptococcus mutans (ATCC 25175), Streptococcus sobrinus (ATCC 33478), and Candida albicans (ATCC 10231) using agar well diffusion assay. The identification of the volatile compounds was performed using gas chromatography-mass spectrometry (GC-MS). Results: The C. nardus essential oil exhibited inhibitory activity against C. albicans at the concentration of 6.25%, whereby the inhibitory activity against S. mutans and S. sobrinus began at the concentration of 25%. The antimicrobial activity of C. nardus essential oil was statistically significant at the concentration of 50% in all tested pathogens. The GC-MS analysis of the C. nardus essential oil revealed the presence of few constituents, which include monoterpenes, diterpenes, sesquiterpenes and phenolic compounds. Monoterpenes were the major identified terpenoids and contributed to 54.45% of the total volatile composition. The main identified monoterpenes were citronellal (11.35%), z-Citral (11.34%), β-Myrcene (6.70%), and β-Trans-ocimene (6.03%), which was the first time β-Myrcene and β-Trans-ocimene was found in high percentage. Conclusion: C. nardus essential oil is an active antibacterial agent against several oral pathogens, and the percentages of active volatile compounds are different within different origins.

scholarly journals Antimicrobial efficacy of five essential oils against oral pathogens: An in vitro study

2013 ◽  
Vol 07 (S 01) ◽  
pp. S071-S077 ◽  
Author(s):  
Nilima Thosar ◽  
Silpi Basak ◽  
Rakesh N. Bahadure ◽  
Monali Rajurkar
Keyword(s):  
Essential Oils ◽  
Antimicrobial Activities ◽  
Dilution Method ◽  
Peppermint Oil ◽  
Tea Tree Oil ◽  
Lavender Oil ◽  
Tea Tree ◽  
Thyme Oil ◽  
Oral Pathogens

ABSTRACT Objectives: This study was aimed to find out the minimum inhibitory concentration (MIC) of five essential oils against oral pathogens and to find out the minimum bactericidal concentration (MBC) and minimum fungicidal concentration (MFC) of five essential oils against oral pathogens. Materials and Methods: The antimicrobial activities by detecting MIC and MBC/MFC of five essential oils such as tea tree oil, lavender oil, thyme oil, peppermint oil and eugenol oil were evaluated against four common oral pathogens by broth dilution method. The strains used for the study were Staphylococcus aureus ATCC 25923, Enterococcus fecalis ATCC 29212, Escherichia coli ATCC 25922 and Candida albicans ATCC 90028. Results: Out of five essential oils, eugenol oil, peppermint oil, tea tree oil exhibited significant inhibitory effect with mean MIC of 0.62 ± 0.45, 9.00 ± 15.34, 17.12 ± 31.25 subsequently. Mean MBC/MFC for tea tree oil was 17.12 ± 31.25, for lavender oil 151.00 ± 241.82, for thyme oil 22.00 ± 12.00, for peppermint oil 9.75 ± 14.88 and for eugenol oil 0.62 ± 0.45. E. fecalis exhibited low degree of sensitivity compared with all essential oils. Conclusion: Peppermint, tea tree and thyme oil can act as an effective intracanal antiseptic solution against oral pathogens.

A New Active Compound from Centaurea Species

2006 ◽  
Vol 61 (1-2) ◽  
pp. 44-46 ◽  
Author(s):  
Melek U. Dumlu ◽  
Elcin Gürkan
Keyword(s):  
Active Compound ◽  
Spectroscopic Data ◽  
Chemical Structure ◽  
Sesquiterpene Lactones ◽  
Antimicrobial Activities ◽  
H Nmr ◽  
Steroidal Compound ◽  
Antioxidant And Antimicrobial Activities ◽  
C Nmr

Abstract The extract containing sesquiterpene lactones of Centaurea iberica (Asteraceae) isolated was separated and a steroidal compound, which is stigmast-1,5-dien-3β-ol, was purified. The chemical structure was established based on spectroscopic data (UV, IR, MS, 1H NMR, 13C NMR). Both the extract and the compound showed significant antioxidant and antimicrobial activities

scholarly journals Progressive Applications of Hyperbranched Polymer Based on Diarylamine: Antimicrobial, Anti-Biofilm and Anti-Aerobic Corrosion

Materials ◽  
2020 ◽  
Vol 13 (9) ◽  
pp. 2076
Author(s):  
Khalid I. Kabel ◽  
Ahmed Labena ◽  
Mohamed Keshawy ◽  
Wael N. Hozzein
Keyword(s):  
Corrosion Inhibition ◽  
Methyl Acrylate ◽  
Chemical Structure ◽  
Antimicrobial Activities ◽  
Metal Corrosion ◽  
Gram Negative Bacteria ◽  
One Pot ◽  
Yeast Strains ◽  
1Hnmr Spectroscopy ◽  
Positive Controls

New generations of hyperbranched aramids were synthesized from diarylamine and methyl acrylate using an AB2 monomer approach in a straightforward one-pot preparation. The chemical structure of hyperbranched Phenylenediamine/Methyl Acrylate HB(PDMA was confirmed by Fourier Transform Infrared (FTIR) and Nuclear Magnetic Resonance (1HNMR) spectroscopy. In addition, the particle’s size and distribution were recorded using Dynamic Light Scattering (DLS). Moreover, the synthesized HB(PDMA)s displayed broad-spectrum antimicrobial activities against Gram-positive and Gram-negative bacteria as well as yeast strains and anti-biofilm activity where the highest activity was attributed to HB(PDMA)G4 at the lowest Minimum Inhibitory, Minimum Bactericidal, and Fungicidal Concentrations (MIC, MBC, and MFC, respectively). Furthermore, the HB(PDMA)s expressed anti-bacterial activity against isolated Pseudomonas sp. (R301) at a salinity of 35,000 ppm (NaCl). In addition, they revealed different corrosion inhibition efficiencies at the cultivated medium salinity at the estimated minimum bactericidal concentrations. The highest metal corrosion inhibition efficiencies were 59.5 and 94.3% for HB(PDMA)G4 at the Minimum Bactericidal Concentrations (MBCs) and two times Minimum Bactericidal Concentrations (2XMBCs), respectively, in comparison to both negative and positive controls.

The influence of chemical structure on the antimicrobial activities of thiosemicarbazone-chitosan

Cellulose ◽  
2013 ◽  
Vol 21 (1) ◽  
pp. 105-114 ◽  
Author(s):  
Zhimei Zhong ◽  
Bayaer Aotegen ◽  
Hui Xu ◽  
Shuang Zhao
Keyword(s):  
Chemical Structure ◽  
Antimicrobial Activities
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