scholarly journals Comparison of Carbonate Apatite and .BETA.-tricalcium Phosphate (Resorbable Calcium Phosphates) Implanted Subcutaneously into the Back of Rats

2006 ◽  
Vol 25 (2) ◽  
pp. 219-225 ◽  
Author(s):  
Motohiko NAGAYAMA ◽  
Hiroshi TAKEUCHI ◽  
Yutaka DOI
Keyword(s):  
Tricalcium Phosphate ◽  
Calcium Phosphates ◽  
Carbonate Apatite ◽  
Beta Tricalcium Phosphate

scholarly journals Physico-chemical properties of calcium phosphates

2012 ◽  
Vol 59 (1) ◽  
pp. 7-21 ◽  
Author(s):  
Vesna Babic-Ivancic ◽  
Maja Dutour-Sikiric
Keyword(s):  
Calcium Phosphates ◽  
Chemical Properties ◽  
Organic Matrix ◽  
Octacalcium Phosphate ◽  
Carbonate Apatite ◽  
Organic Additives ◽  
Biologically Relevant ◽  
Beta Tricalcium Phosphate ◽  
Physico Chemical

Calcium phosphates have important role in biological and pathological mineralization. While only one of calcium phosphates, carbonate apatite, represents the main mineral component of teeth and bones, octacalcium phosphate, calcium hydrogenphosphate dihydrate and beta-tricalcium phosphate occur in pathological deposits. From the stand-point of chemists, processes of biological and pathological mineralization could be considered as deposition of inorganic phase within organic matrix, i.e. formation of inorganic-organic composites. Although this approach is very simplified at first glance, it allows clarification of important issues related to biomineralization (e.g. what is the role of individual components of organic matrix in the emerging solid tissue), and design and preparation of new materials for hard tissue regeneration (e.g. process of transformation after implantation). The importance of investigation about calcium phosphates will be presented through the overview of basic physico-chemical reactions related to the formation and transformation of biologically relevant calcium phosphates and their interaction with various organic additives in the laboratory.

scholarly journals Preparation of carbonate apatite scaffolds using different carbonate solution and soaking time

2019 ◽  
Vol 13 (2) ◽  
pp. 139-148 ◽  
Author(s):  
Fadilah Darus ◽  
Mariatti Jaafar ◽  
Nurazreena Ahmad
Keyword(s):  
Compressive Strength ◽  
Aqueous Solutions ◽  
Tricalcium Phosphate ◽  
Average Pore Size ◽  
Carbonate Content ◽  
Precipitation Reaction ◽  
Carbonate Apatite ◽  
Hydrothermal Conversion ◽  
Average Pore ◽  
Beta Tricalcium Phosphate

The aim of this study is to fabricate CO3Ap scaffolds using a dissolution-precipitation reaction during hydrothermal treatment. Beta-tricalcium phosphate (?-TCP) was used as a precursor instead of the commonly used alpha-tricalcium phosphate (?-TCP). Here, the CO3Ap scaffold fabrication was accomplished in two steps: i) fabrication of ?-TCP scaffold using a combination of direct foaming and a sacrificial template and ii) hydrothermal conversion of the ?-TCP scaffold at 200?C in 2mol/l NaHCO3 and Na2CO3 aqueous solutions for 2-10 days. The effect of two different solutions was identified in the dissolution-precipitation reaction. CO3Ap scaffold with 8.95wt.% carbonate content was successfully fabricated using a NaHCO3 solution. The average pore size of the scaffold was approximately 180 ?m with 72% porosity. The average compressive strength of the CO3Ap scaffold was 0.7MPa. Based on the compressive strength and carbonate content results, NaHCO3 aqueous solutions were chosen as carbonate sources for phase transformation to fabricate a CO3Ap scaffold over 6 days.

Microstructured β-Tricalcium Phosphate Putty versus Autologous Bone for Repair of Alveolar Clefts in a Goat Model

2017 ◽  
Vol 54 (6) ◽  
pp. 699-706 ◽  
Author(s):  
Nard G. Janssen ◽  
Adrianus P. de Ruiter ◽  
Wouter M.M.T. van Hout ◽  
Vincent van Miegem ◽  
Debby Gawlitta ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Tricalcium Phosphate ◽  
Gold Standard ◽  
Calcium Phosphates ◽  
The Other ◽  
Clinical Use ◽  
Alveolar Cleft ◽  
Beta Tricalcium Phosphate ◽  
Autologous Bone ◽  
First Time

For the first time it was demonstrated that an osteoinductive calcium phosphate-based putty is effective in the restoration of complex maxillofacial defects. In these defects, adequate mechanical confinement by multiple bony walls and osteoconduction from multiple surfaces are usually lacking. This study compares the efficacy of a microstructured beta-tricalcium phosphate (β-TCP) putty with autologous bone for the repair of alveolar cleft defects. A total of 10 Dutch milk goats were operated on in a split-mouth study design in which two-wall bony alveolar clefts were created and successively repaired with autologous bone (the gold standard) at one side and β-TCP putty at the other. After 24 weeks of implantation, histomorphometric and micro–computer tomography analyses proved that the β-TCP putty group showed equal bone quality and volume to clefts reconstructed with autologous bone. In addition, surgical handling of the putty is superior to the use of calcium phosphates in a granular form. Therefore, the results of this study open a clear trajectory for the clinical use of β-TCP putty in the reconstruction of the alveolar cleft and other challenging two-wall bony defects.

scholarly journals Liposomal clodronate inhibition of osteoclastogenesis and osteoinduction by submicrostructured beta-tricalcium phosphate

Biomaterials ◽  
2014 ◽  
Vol 35 (19) ◽  
pp. 5088-5097 ◽  
Author(s):  
Noel L. Davison ◽  
Anne-Laure Gamblin ◽  
Pierre Layrolle ◽  
Huipin Yuan ◽  
Joost D. de Bruijn ◽  
...  
Keyword(s):  
Tricalcium Phosphate ◽  
Beta Tricalcium Phosphate ◽  
Liposomal Clodronate

scholarly journals Heparinization of Beta Tricalcium Phosphate: Osteo-immunomodulatory Effects

2017 ◽  
Vol 7 (5) ◽  
pp. 1700867 ◽  
Author(s):  
Anna Diez-Escudero ◽  
Montserrat Espanol ◽  
Mar Bonany ◽  
Xi Lu ◽  
Cecilia Persson ◽  
...  
Keyword(s):  
Tricalcium Phosphate ◽  
Immunomodulatory Effects ◽  
Beta Tricalcium Phosphate

Surface Modification of Nanosized Biphasic α-TCP/HA Powders

2007 ◽  
Vol 330-332 ◽  
pp. 223-226 ◽  
Author(s):  
Li Li Pan ◽  
Yan Bao Li ◽  
Chao Zou ◽  
Wen Jian Weng ◽  
Kui Cheng ◽  
...  
Keyword(s):  
Surface Modification ◽  
Stearic Acid ◽  
Tricalcium Phosphate ◽  
Calcium Phosphates ◽  
Biological Characteristics ◽  
Buffer Solution ◽  
Solution Ph

Stearic acid was utilized to modify biphasic alpha-tricalcium phosphate (α-TCP)/hydroxyapatite (HA) powders in the ethanol. The results showed that the dispersion of biphasic α-TCP/HA powders (BCPs) in non-polar matrix improved. And the released content of Ca2+ and PO4 3- of the BCPs soaked in the NaAc-HAc buffer solution (pH 5.0) was almost same as that before modification. Stearic acid could modify the suface properties of BCPs and would not obviously affect their biological characteristics, which affords a good groundwork of application of calcium phosphates powders.

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