scholarly journals Erratum to: Back to the multi-step adhesive system: A next-generation two-step system with hydrophobic bonding agent improves bonding effectiveness

2021 ◽  
Vol 40 (5) ◽  
pp. 1290-1290
Author(s):  
Azusa YAMANAKA ◽  
Atsushi MINE ◽  
Mariko MATSUMOTO ◽  
Ryosuke HAGINO ◽  
Masahiro YUMITATE ◽  
...  
Author(s):  
Azusa YAMANAKA ◽  
Atsushi MINE ◽  
Mariko MATSUMOTO ◽  
Ryosuke HAGINO ◽  
Masahiro YUMITATE ◽  
...  

2021 ◽  
Vol 11 (1-s) ◽  
pp. 147-153
Author(s):  
Pawankumar H Yadav ◽  
Dipak P Kardile ◽  
Madhuri T Deshmukh ◽  
Rajkumar V. Shete

The most suitable drug delivery route is oral delivery due to its easily administration, patient adherence/ patient capacitance etc. Several approaches have been made for maximizing the G.R.T such as high-density system, floating system, swelling & expanding system and mucoadhesive & bio adhesive system etc. the main motive of reviewing the article is to focus on the mechanism of HBS system, classification with new system such as raft forming system and hollow microsphere, its application, marketed preparation and evaluation study. The procedure of gastric emptying is a complex and may leads to uncertainty for in vivo performance of the DDS. To prevent this type of complex formation and uncertainty, hard work has been done to expand the retention time of DDS for half of the day. The FDDS are beneficial in such process. Keywords: HBS system, GRDDS, gastric residence time (G.R.T), raft forming systems, floating formulations, evaluation study. 


Author(s):  
Rizacan Sarikaya ◽  
Linyong Song ◽  
Esra Yuca ◽  
Sheng-Xue Xie ◽  
Kyle Boone ◽  
...  

2020 ◽  
Author(s):  
JP Townsend ◽  
GOT Merces ◽  
GP Castellanos ◽  
M Pickering

AbstractCtenophores are a group of largely-planktonic, gelatinous carnivores whose most common method of prey capture is nearly a phylum-defining trait. Tentaculate ctenophores release an unknown proteinaceous adhesive from specialized colloblast cells lining their tentacles following prey contact with the tentacles. There exist no extant studies of the mechanical properties of colloblast adhesive. We use live microscopy techniques to visualize adhesion events between Pleurobrachia pileus colloblasts and probes of different surface chemistries in response to probing with varying contact areas. We further define two mechanisms of adhesion termination upon probe retraction. Adapting a technique for measuring surface tension, we examine the adhesive strength of tentacles in the ctenophore Pleurobrachia bachei under varying pH and bonding time conditions, and demonstrate the destructive exhaustion of colloblast adhesive release. We find that colloblast-mediated adhesion is rapid, and that the bonding process is robust against shifts in ambient pH. However, we find that the Pleurobrachia colloblast adhesive system is among the weakest biological adhesive systems yet described. We place this surprising observation into a broader ecophysiological context by modeling prey capture for prey of a range of sizes. We find that limited use of colloblast adhesive with high surface area contact is suitable both for capturing appropriately sized prey and rejecting, by detachment, prey above a certain size threshold. This allows Pleuro-brachia, lacking a mechanism to directly “see” potential prey they are interacting with, to invest in capturing only prey of an appropriate size, decreasing the risk of injury.Summary statementCtenophore colloblast adhesive is found to be strong, but few colloblasts are simultaneously active, producing a weakly-adhering system. A physical model demonstrates how such a system may filter unsuitable prey.


Gland Surgery ◽  
2019 ◽  
Vol 8 (6) ◽  
pp. 644-647
Author(s):  
Jason Y. K. Chan ◽  
Yoon W. Koh ◽  
Jeremy Richmon ◽  
Jaewook Kim ◽  
F. Christopher Holsinger ◽  
...  

2010 ◽  
Vol 5 (6) ◽  
pp. 692-697 ◽  
Author(s):  
Ian Meredith ◽  
Stephen Worthley ◽  
Robert Whitbourn ◽  
Darren Walters ◽  
Dougal McClean ◽  
...  

1993 ◽  
Author(s):  
Kathryn Wurster ◽  
Lawrence Rowell ◽  
Lewis Peach, Jr.

2021 ◽  
Vol 22 (12) ◽  
pp. 6552
Author(s):  
Esra Yuca ◽  
Sheng-Xue Xie ◽  
Linyong Song ◽  
Kyle Boone ◽  
Nilan Kamathewatta ◽  
...  

Resin-based composite materials have been widely used in restorative dental materials due to their aesthetic, mechanical, and physical properties. However, they still encounter clinical shortcomings mainly due to recurrent decay that develops at the composite-tooth interface. The low-viscosity adhesive that bonds the composite to the tooth is intended to seal this interface, but the adhesive seal is inherently defective and readily damaged by acids, enzymes, and oral fluids. Bacteria infiltrate the resulting gaps at the composite-tooth interface and bacterial by-products demineralize the tooth and erode the adhesive. These activities lead to wider and deeper gaps that provide an ideal environment for bacteria to proliferate. This complex degradation process mediated by several biological and environmental factors damages the tooth, destroys the adhesive seal, and ultimately, leads to failure of the composite restoration. This paper describes a co-tethered dual peptide-polymer system to address composite-tooth interface vulnerability. The adhesive system incorporates an antimicrobial peptide to inhibit bacterial attack and a hydroxyapatite-binding peptide to promote remineralization of damaged tooth structure. A designer spacer sequence was incorporated into each peptide sequence to not only provide a conjugation site for methacrylate (MA) monomer but also to retain active peptide conformations and enhance the display of the peptides in the material. The resulting MA-antimicrobial peptides and MA-remineralization peptides were copolymerized into dental adhesives formulations. The results on the adhesive system composed of co-tethered peptides demonstrated both strong metabolic inhibition of S. mutans and localized calcium phosphate remineralization. Overall, the result offers a reconfigurable and tunable peptide-polymer hybrid system as next-generation adhesives to address composite-tooth interface vulnerability.


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