scholarly journals Effects of dialysate calcium concentration on calcium-phosphorus metabolism in hemodialysis patients

2010 ◽  
Vol 43 (11) ◽  
pp. 933-938
Author(s):  
Nobuo Shinkai ◽  
Masahiro Yanase ◽  
Yuki Kyoda ◽  
Motoi Takeuchi ◽  
Fumiyasu Takei ◽  
...  
Keyword(s):  
Calcium Concentration ◽  
Hemodialysis Patients ◽  
Phosphorus Metabolism ◽  
Calcium Phosphorus ◽  
Dialysate Calcium

Ectopic Calcification of Fibrin Sheath on the Catheter

2019 ◽  
Vol 47 (4) ◽  
pp. 327-329 ◽  
Author(s):  
Lan Jia ◽  
Lihua Wang ◽  
Fang Wei ◽  
Aili Jiang
Keyword(s):  
Hemodialysis Patients ◽  
Ectopic Calcification ◽  
Phosphorus Metabolism ◽  
Fibrous Sheath ◽  
Hemodialysis Catheter ◽  
Metabolism Disorder ◽  
Fibrin Sheath ◽  
Calcium Phosphorus ◽  
Clinical Awareness

We describe a case of hemodialysis catheter that appeared to be encased in a sleeve-shaped fibrous sheath with calcification. Ectopic calcification is a serious complication in hemodialysis patients with calcium-phosphorus metabolism disorder. Clinical awareness and understanding of this condition is imperative to the prevention and management of ectopic calcification.

Impact of lowering dialysate calcium concentration on serum bone turnover markers in hemodialysis patients

Bone ◽  
2005 ◽  
Vol 36 (5) ◽  
pp. 909-916 ◽  
Author(s):  
T HAMANO ◽  
S OSETO ◽  
N FUJII ◽  
T ITO ◽  
M KATAYAMA ◽  
...  
Keyword(s):  
Bone Turnover ◽  
Bone Turnover Markers ◽  
Calcium Concentration ◽  
Hemodialysis Patients ◽  
Turnover Markers ◽  
Dialysate Calcium

scholarly journals Impact of Dialysate Calcium Concentration on Clinical Outcomes in Incident Hemodialysis Patients

Medicine ◽  
2015 ◽  
Vol 94 (40) ◽  
pp. e1694 ◽  
Author(s):  
Hyung Wook Kim ◽  
Su-Hyun Kim ◽  
Young Ok Kim ◽  
Dong Chan Jin ◽  
Ho Chul Song ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Calcium Concentration ◽  
Hemodialysis Patients ◽  
Dialysate Calcium

Effects of low dialysate calcium concentration on health-related quality of life in hemodialysis patients

2005 ◽  
Vol 9 (2) ◽  
pp. 153-157 ◽  
Author(s):  
Yoshinori Taji ◽  
Takeshi Morimoto ◽  
Shunichi Fukuhara ◽  
Tsuguya Fukui ◽  
Takashi Kuwahara
Keyword(s):  
Quality Of Life ◽  
Calcium Concentration ◽  
Hemodialysis Patients ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Dialysate Calcium

scholarly journals The change of the dialysate calcium concentration from 3.0 to 2.75mEq/L did not affect the serum PTH level in hemodialysis patients

2012 ◽  
Vol 45 (9) ◽  
pp. 873-880 ◽  
Author(s):  
Akiko Matsuura ◽  
Daisuke Inaguma ◽  
Daisuke Itawaki ◽  
Tomoko Sumi ◽  
Hoshiaki Nakagawa ◽  
...  
Keyword(s):  
Calcium Concentration ◽  
Hemodialysis Patients ◽  
Serum Pth ◽  
Dialysate Calcium ◽  
Pth Level

P1417ALTERED CATHEPSIN-K LEVELS REFLECT SEVERITY OF MINERAL BONE DISEASE AND INFLAMMATION IN CHRONIC HEMODIALYSIS PATIENTS

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Giuseppe Coppolino ◽  
Marta Greco ◽  
Giuseppe Leonardi ◽  
Michele Provenzano ◽  
Omar Tripolino ◽  
...  
Keyword(s):  
Bone Disease ◽  
Calcium Concentration ◽  
Cathepsin K ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis ◽  
Future Research ◽  
Dialysis Session ◽  
Dialysis Patients ◽  
Dialysis Vintage ◽  
Dialysate Calcium

Abstract Background and Aims Mineral bone disease (MBD) and chronic inflammation are key triggers of the exceeding cardiovascular risk that characterizes dialysis patients. Cathepsin-K (Cts-K) is a lysosomal cysteine protease involved in bone remodeling and resorption, whose expression is promoted particularly by inflammation and whose involvement in bone and cardiovascular disorders has previously been demonstrated. We set out to undertake an exploratory, observational study to assess the possible clinical significance of Cts-K in dialysis patients. Method Eighty-five chronic HD patients (mean age 67±12, median dialysis vintage 3.2 yrs) with stable dry weight were studied. Cts-K was measured in peripheral blood samples before a mid-week dialysis session together with standard biochemical parameters. Twenty-six healthy subjects, matched with HD patients for age and gender, served as controls. Results Cts-K was statistically higher in HD patients than in controls (median 340, IQR 170-835 vs. 190 IQR 20-120 pg/mL, p<0.0001). At univariate analyses, Cts-K levels were significantly associated with ALP (r=0.50, p<0.001), CRP (r=0.46, p<0.001), PTH (r=0.24,p=0.02), presence of diabetes (r=0.28,p<0.001),peripheral vasculopathy (r=0.20, p=0.05) and dialysate calcium concentration (r=-0.28,p<0.001). In a multivariate model including all univariate predictors (R2=61%, p<0.001) only ALP (β=0.70,p<0.001), CRP (β=0.49,p<0.001) and dialysate calcium concentration (β -0.40,p=0.04) remained significantly associated with Cts-K levels. Interestingly, Cts-K levels were significantly higher among individuals who were under active calcimimetic therapy (n=28; p<0.001) but significantly lower among those who previously underwent parathyroidectomy (n=8; p<0.001) (Figure 1). Conclusion Cathepsin-K is a biomarker at the crossroads of bone and inflammatory disorders in chronic hemodialysis patients. Future research is needed to clarify the exact pathophysiological role of this protein and to test its potential usefulness as a marker for managing MBD therapy and complications.

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