Regional cerebral blood flow analysis of vascular dementia by the 133Xe inhalation method

Nosotchu ◽  
1987 ◽  
Vol 9 (2) ◽  
pp. 107-111
Author(s):  
Sho Watanabe ◽  
Koichi Miyakawa ◽  
Michiyuki Maruyama ◽  
Gonbei Kamijima ◽  
Yasuto Sasaki
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Vascular Dementia ◽  
Regional Cerebral Blood Flow ◽  
Flow Analysis ◽  
Regional Cerebral Blood ◽  
Blood Flow Analysis

Pitfalls of Regional Cerebral Blood Flow Analysis in Cerebrovascular Disease

1988 ◽  
Vol 13 (3) ◽  
pp. 197-201 ◽  
Author(s):  
HANS L. LAGREZE ◽  
ROSS L. LEVINE ◽  
JOHN S. SUNDERLAND ◽  
ROBERT J. NICKLES
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Cerebrovascular Disease ◽  
Regional Cerebral Blood Flow ◽  
Flow Analysis ◽  
Regional Cerebral Blood ◽  
Blood Flow Analysis

Radical surgery of a galenic aneurysm with regional cerebral blood flow analysis

1989 ◽  
Vol 31 (1) ◽  
pp. 58-63 ◽  
Author(s):  
Hideichi Takayama ◽  
Takeshi Kawase ◽  
Kiyotaka Tamura ◽  
Kohichi Uchida ◽  
Shigeo Toya
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Regional Cerebral Blood Flow ◽  
Radical Surgery ◽  
Flow Analysis ◽  
Regional Cerebral Blood ◽  
Blood Flow Analysis

scholarly journals Nimodipine Improves Regional Cerebral Blood Flow and Suppresses Inflammatory Factors in the Hippocampus of Rats with Vascular Dementia

2012 ◽  
Vol 40 (3) ◽  
pp. 1036-1045 ◽  
Author(s):  
X-L Zhang ◽  
S-L Zheng ◽  
F-R Dong ◽  
Z-M Wang
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Vascular Dementia ◽  
Regional Cerebral Blood Flow ◽  
Learning Ability ◽  
Inflammatory Factors ◽  
Morris Water Maze Test ◽  
Regional Cerebral Blood ◽  
Tnf Α ◽  
Group D

OBJECTIVE: To study the effect of nimodipine on hippocampal regional cerebral blood flow (rCBF) and proinflammatory cytokines in rats with experimental vascular dementia. METHODS: Male Sprague Dawley rats were randomly divided into four groups ( n = 15/group): sham operated controls (group A); focal cerebral ischaemia (group B); vascular dementia (group C); and vascular dementia treated with 20 mg/kg nimodipine daily (group D). The Morris water maze test evaluated learning and memory, and magnetic resonance perfusion-weighted imaging was used to measure rCBF. Hippocampal levels of nuclear factor-κB (NF-κB), tumour necrosis factor-α (TNF-α) and interleukin 1β (IL-1β) were measured. RESULTS: Compared with group C, rats in group D demonstrated significantly improved learning ability and significantly increased hippocampal rCBF. The levels of NF-κB, TNF-α and IL-1β were significantly lower in group D than in group C. Hippocampal nerve cell morphology was abnormal in group C but near normal in group D. CONCLUSIONS: Nimodipine improved the symptoms of cognitive impairment, increased rCBF, reduced hippocampal cytokine levels and alleviated neuronal injury in the hippocampus of rats with experimental vascular dementia.

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