scholarly journals Assessment of cerebral ischemia using near infrared optical topography with inhalation of oxygen

Nosotchu ◽  
2009 ◽  
Vol 31 (6) ◽  
pp. 483-490
Author(s):  
Akira Ebihara ◽  
Takehiko Konno ◽  
Yuichi Tanaka ◽  
Eiju Watanabe
Author(s):  
Yuichi Tanaka ◽  
Akira Ebihara ◽  
Masashi Ikota ◽  
Tomotaka Yamaguro ◽  
Haruna Kamochi ◽  
...  

2010 ◽  
Vol 121 (7) ◽  
pp. e29
Author(s):  
Akira Ebihara ◽  
Takehiko Konno ◽  
Yuichi Tanaka ◽  
Eiju Watanabe

2009 ◽  
Vol 120 (5) ◽  
pp. e147-e148
Author(s):  
Akira Ebihara ◽  
Yuichi Tanaka ◽  
Eiju Watanabe

1998 ◽  
Vol 89 (3) ◽  
pp. 389-394 ◽  
Author(s):  
Peter J. Kirkpatrick ◽  
Joseph Lam ◽  
Pippa Al-Rawi ◽  
Piotr Smielewski ◽  
Marek Czosnyka

Object. Signal changes in adult extracranial tissues may have a profound effect on cerebral near-infrared spectroscopy (NIRS) measurements. During carotid surgery NIRS signals provide the opportunity to determine the relative contributions from the intra- and extracranial vascular territories, allowing for a more accurate quantification. In this study the authors applied multimodal monitoring methods to patients undergoing carotid endarterectomy and explored the hypothesis that NIRS can define thresholds for cerebral ischemia, provided extracranial NIRS signal changes are identified and removed. Relative criteria for intraoperative severe cerebral ischemia (SCI) were applied to 103 patients undergoing carotid endarterectomy. Methods. One hundred three patients underwent carotid endarterectomy. An intraoperative fall in transcranial Doppler—detected middle cerebral artery flow velocity (%ΔFV) of greater than 60% accompanied by a sustained fall in cortical electrical activity were adopted as criteria for SCI. Ipsilateral frontal NIRS recorded the total difference in concentrations of oxyhemoglobin and deoxyhemoglobin (Total ΔHbdiff). Interrupted time series analysis following clamping of the external carotid artery (ECA) and the internal carotid artery (ICA) allowed the different vascular components of Total ΔHbdiff (ECA ΔHbdiff and ICA ΔHbdiff) to be identified. Data obtained in 76 patients were deemed suitable. A good correlation between %ΔFV and ICA ΔHbdiff (r = 0.73, p < 0.0001) was evident. Sixteen patients (21%) fulfilled the criteria for SCI. All patients who demonstrated an ICA ΔHbdiff of greater than 6.8 µmol/L showed SCI, and in two patients within this group nondisabling watershed infarction developed, as seen on postoperative computerized tomography scans. No patient with an ICA ΔHbdiff less than 5 µmol/L exhibited SCI or suffered a stroke. Within the resolution of the criteria used an ICA ΔHbdiff threshold of 6.8 µmol/L provided 100% specificity for SCI, whereas an ICA ΔHbdiff less than 5 µmol/L was 100% sensitive for excluding SCI. When Total ΔHbdiff was used without removing the ECA component, no thresholds for SCI were apparent. Conclusions. Carotid endarterectomy provides a stable environment for exploring NIRS-quantified thresholds for SCI in the adult head.


2003 ◽  
Vol 100 (19) ◽  
pp. 10722-10727 ◽  
Author(s):  
G. Taga ◽  
K. Asakawa ◽  
A. Maki ◽  
Y. Konishi ◽  
H. Koizumi

2012 ◽  
Vol 17 (9) ◽  
pp. 0960021 ◽  
Author(s):  
Akira Ebihara ◽  
Yuichi Tanaka ◽  
Takehiko Konno ◽  
Shingo Kawasaki ◽  
Michiyuki Fujiwara ◽  
...  

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