scholarly journals Haplotype-Based case-control study of the STRK1 region on 5q12 in cerebral infarction

Nosotchu ◽  
2006 ◽  
Vol 28 (4) ◽  
pp. 590-595
Author(s):  
Tomohiro Nakayama ◽  
Satoshi Asai ◽  
Naoyuki Sato ◽  
Masayoshi Soma
Keyword(s):  
Cerebral Infarction ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals Cerebral infarction in advanced non-small cell lung cancer: a case control study

BMC Cancer ◽  
2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Motoyasu Kato ◽  
Takehito Shukuya ◽  
Keita Mori ◽  
Ryota Kanemaru ◽  
Yuichiro Honma ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cerebral Infarction ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Small Cell ◽  
Small Cell Lung ◽  
Control Study

scholarly journals Association between CTSS gene polymorphism and the risk of acute atherosclerotic cerebral infarction in Chinese population: a case–control study

2018 ◽  
Vol 38 (6) ◽  
Author(s):  
Lian Luo ◽  
Mingli Zhu ◽  
Jiajun Zhou
Keyword(s):  
Cerebral Infarction ◽  
Case Control Study ◽  
Case Control ◽  
Cathepsin S ◽  
Control Group ◽  
Study Group ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Independent Risk Factors ◽  
Control Study

Objective: To investigate the association between the gene polymorphisms of rs774320676, rs768437857, rs928508030, and rs2275235 loci of Cathepsin S (CTSS) and risk of acute atherosclerotic cerebral infarction. Methods: A total of 315 patients with acute atherosclerotic cerebral infarction (study group) and 220 healthy subjects (control group) were enrolled in the present study. The genetic polymorphism of rs774320676, rs768437857, rs928508030, and rs2275235 loci of CTSS of subjects was analyzed by PCR-Sanger sequencing. Results: The proportion of carriers with mutant T allele at rs774320676 locus and mutant G allele at rs928508030 locus of CTSS in study group was significantly higher than the proportion in control group (P=0.000, adjusted odds ratio (OR) = 1.332, 95% confidence interval (CI) = 1.200–1.460; P<0.001, adjusted OR = 1.185, 95% CI = 1.055–1.314; P=0.002). The T allele at rs774320676 locus and the G allele at rs928508030 locus of CTSS were independent risk factors for acute atherosclerotic cerebral infarction (OR = 2.534, 95% CI = 1.020–4.652, P=0.006; OR = 2.016, 95% CI = 1.031–4.385, P=0.031). Conclusion: The single nucleotide polymorphisms (SNPs) of rs774320676 and rs928508030 of CTSS gene were related with risk for acute atherosclerotic cerebral infarction. The T allele at rs774320676 locus and G allele at rs928508030 locus of CTSS were genetic susceptibility genes of acute atherosclerotic cerebral infarction.

scholarly journals Association of extracellular superoxide dismutase gene with cerebral infarction in women: a haplotype-based case-control study

Hereditas ◽  
2008 ◽  
Vol 145 (6) ◽  
pp. 283-292 ◽  
Author(s):  
Takahiro Naganuma ◽  
Tomohiro Nakayama ◽  
Naoyuki Sato ◽  
Zhenyan Fu ◽  
Masayoshi Soma ◽  
...  
Keyword(s):  
Superoxide Dismutase ◽  
Cerebral Infarction ◽  
Case Control Study ◽  
Case Control ◽  
Extracellular Superoxide Dismutase ◽  
Superoxide Dismutase Gene ◽  
Control Study

scholarly journals Association of the smoothelin (SMTN) gene with cerebral infarction in men: A haplotype-based case–control study

2012 ◽  
Vol 17 (5) ◽  
pp. 317-325 ◽  
Author(s):  
Jie Jiang ◽  
Tomohiro Nakayama ◽  
Masanori Shimodaira ◽  
Naoyuki Sato ◽  
Noriko Aoi ◽  
...  
Keyword(s):  
Cerebral Infarction ◽  
Case Control Study ◽  
Case Control ◽  
Control Study
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