Secondary Metabolites by Chemical Screening 14. Transformation of Elaiophylin in subunits of Naturally Occurring Acid Ionophores: Synthesis, Anticoccidial Activity and Studies Concerning the Ionophoric Properties

Heterocycles ◽  
1991 ◽  
Vol 32 (8) ◽  
pp. 1471
Author(s):  
Peter Hammann ◽  
Gerhard Kretzschmar ◽  
Robert Klein ◽  
Maria Kajtár-Peredy ◽  
Achim Kröger ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Chemical Screening ◽  
Naturally Occurring ◽  
Anticoccidial Activity

Screening for naturally occurring oxyprenylated secondary metabolites as cancer cell growth inhibitory agents

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
F Epifano ◽  
S Genovese ◽  
P Lullo ◽  
S Fiorito ◽  
G Trivisonno ◽  
...  
Keyword(s):  
Cell Growth ◽  
Secondary Metabolites ◽  
Cancer Cell ◽  
Cancer Cell Growth ◽  
Naturally Occurring ◽  
Growth Inhibitory ◽  
Inhibitory Agents

UJI IMUNOSTIMULATOR DARI KOMBINASI EKSTRAK ETANOL HERBA BINARA (ARTEMISIA VULGARIS LINN) DAN EKSTRAK ETANOL DAUN PUCUK MERAH (SYZYGIUM OLEANA) DENGAN METODE HIPERSENSITIVITAS TIPE LAMBAT PADA TIKUS JANTAN

2019 ◽  
Vol 1 (2) ◽  
pp. 22-26
Author(s):  
Romauli Anna Teresia Marbun ◽  
Aminah Syarifuddin ◽  
Montysory Silalahi ◽  
Radika Bella Fista Ginting
Keyword(s):  
Antioxidant Activity ◽  
Immune System ◽  
Secondary Metabolites ◽  
Ethanol Extract ◽  
Positive Control ◽  
Artemisia Vulgaris ◽  
Chemical Screening ◽  
Chemical Content ◽  
High Antioxidant Activity ◽  
New Treatments

Diseases mediated by the immune system are difficult problems to treat such as human immunodeficiency virus (HIV) and other lethal viruses. Infections that occur in normal people are generally brief and rarely leave permanent damage. Treatment of this disease requires an aggressive and innovative approach to the development of new treatments so that it requires the role of immunomodulators to improve the immune system. A substance that acts as an enhancer or immune enhancer can be obtained by using herbs that are efficacious as immunostimulants. One of the herbs used is herbal binara (Artemisia vulgaris L) which has been studied as a potential immunomodulator with high antioxidant activity. Previous research also stated that red shoots (Syzygium oleana) were studied as potential immunomodulators with high antioxidant activity. Several other species such as Syzygium samarangense have 16 flavonoida compounds which show pharmacological immunological activity. The purpose of this study was to determine the content of secondary metabolites of ethanol extract of herbal binara (Artemisia vulgaris L.) with red shoots (Syzygium oleana) and to determine the best dose of extract from the ethanol extract of herbal binara (Artemisia vulgaris L.) with red shoots (Syzygium oleana) can reduce the volume of swelling of mouse feet. Examination of the chemical content of secondary metabolites from the ethanol extract of herbal binara (Artemisia vulgaris L.) with red shoots (Syzygium oleana) is carried out by chemical screening and characterization of simplicia and extract. The method used is the slow type hypersensitivity method. In this test the independent variable is the secondary metabolite of ethanol extract of herb binara (Artemisia vulgaris L.) with red shoots (Syzygium oleana) with four concentrations (50, 100, 200 and 400 mg / kgBB). The positive control used by Stimuno dose is 32.5 mg / kgBB

scholarly journals Secondary metabolites by chemical screening 4. Detection, isolation and biological activities of chiral synthons from Streptomyces.

1991 ◽  
Vol 44 (7) ◽  
pp. 797-800 ◽  
Author(s):  
SUSANNE GRABLEY ◽  
PETER HAMMANN ◽  
HEINZ KLUGE ◽  
JOACHIM WINK ◽  
PETRA KRICKE ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Biological Activities ◽  
Chemical Screening

ChemInform Abstract: Secondary Metabolites by Chemical Screening. Part 18. Narbosines, New Carbohydrate Metabolites from Streptomyces.

ChemInform ◽  
2010 ◽  
Vol 22 (35) ◽  
pp. no-no
Author(s):  
T. HENKEL ◽  
S. BREIDING-MACK ◽  
A. ZEECK ◽  
S. GRABLEY ◽  
P. E. HAMMANN ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Chemical Screening ◽  
Carbohydrate Metabolites

scholarly journals Bioactive Compounds from Brassicaceae: a Beneficial Contribution in our Everyday Diet

2011 ◽  
Vol 68 (2) ◽  
Author(s):  
Renato IORI ◽  
Gina R. DE NICOLA ◽  
Manuela BAGATTA ◽  
Eleonora PAGNOTTA
Keyword(s):  
Secondary Metabolites ◽  
Dietary Intake ◽  
Bioactive Compounds ◽  
Chemical Structure ◽  
Side Chain ◽  
Variable Part ◽  
Naturally Occurring ◽  
Interesting Class

Dietary intake of Brassicaceae (Crucifers) provides not only nutrients, but also a highly interesting class of secondary metabolites beneficial to health, known as glucosinolates (GLs). These compounds possess a -D-glucopyranosyl unit connected to a O-sulfated anomeric Z-thiohydroximate function, and a side chain R which is the only variable part of the chemical structure. Up to now, more than 120 naturally-occurring GLs have been carachterized

scholarly journals γ-Butyrolactones from Aspergillus Species: Structures, Biosynthesis, and Biological Activities

2017 ◽  
Vol 12 (5) ◽  
pp. 1934578X1701200 ◽  
Author(s):  
Sabrin R. M. Ibrahim ◽  
Gamal A. Mohamed ◽  
Amgad I.M. Khedr
Keyword(s):  
Secondary Metabolites ◽  
Biological Activities ◽  
Rich Source ◽  
Aspergillus Species ◽  
Aromatic Rings ◽  
Naturally Occurring ◽  
Fungal Secondary Metabolites

Recently, numerous metabolites possessing uncommon structures and potent bioactivity have been isolated from strains of fungi collected from diverse environments. The genus Aspergillus is known as a rich source of γ-butyrolactones. These are a group of fungal secondary metabolites, consisting of a five-membered lactone bearing two aromatic rings, which shows a great variety of biological activities. This review summarizes the research on the biosynthesis, source, and biological activities of the naturally occurring γ-butyrolactones that have been isolated from Aspergillus species published over the last decades. More than 75 compounds are described and 65 references are cited.

Secondary Metabolites by Chemical Screening, 28. Aspinonene, a New Multifunctional Fungal Metabolite

1994 ◽  
Vol 1994 (8) ◽  
pp. 831-835 ◽  
Author(s):  
Jens Fuchser ◽  
Susanne Grabley ◽  
Mathias Noltemeyer ◽  
Siegrid Philipps ◽  
Ralf Thiericke ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Fungal Metabolite ◽  
Chemical Screening

Secondary Metabolites by Chemical Screening, 24. Oasomycins, New Macrolactones of the Desertomycin Family

1993 ◽  
Vol 1993 (5) ◽  
pp. 573-579 ◽  
Author(s):  
Susanne Grabley ◽  
Gerhard Kretzschmar ◽  
Marion Mayer ◽  
Siegrid Philipps ◽  
Ralf Thiericke ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Chemical Screening

Acremonium endophytes in perennial ryegrass and other pasture grasses in Australia and New Zealand

1992 ◽  
Vol 43 (8) ◽  
pp. 1683 ◽  
Author(s):  
R. van Heeswijck ◽  
G. McDonald
Keyword(s):  
New Zealand ◽  
Secondary Metabolites ◽  
Fungal Endophytes ◽  
Current Status ◽  
Fescue Toxicosis ◽  
Naturally Occurring ◽  
Resistance To Insects ◽  
Pasture Grasses ◽  
Grazing Systems ◽  
The Impact

Many grasses contain asymptomatic fungal endophytes which are now recognised as having a major impact on the performance of pastures in Australia and New Zealand, and elsewhere in the world. The association between the plant and the fungus is regarded as mutualistic, with the host grass able to benefit from endophyte presence through reduced herbivore feeding, increased resistance to insects, improved plant growth and possibly disease resistance. Grazing systems may be disadvantaged, however, as the ingestion of endophyte-infected grasses can be associated with a number of animal toxicoses including ryegrass staggers and fescue toxicosis. There is increasing evidence that the effects of endophyte on the host grass, and consequently on pasture performance and animal production, are mediated by a range of secondary metabolites produced by the plant-fungus interaction. Recent work has shown that a great deal of variation can be found amongst endophyte strains both in the types and amounts of these secondary metabolites produced. This review presents the current status of knowledge on the impact of endophyte on pasture grasses in Australia and New Zealand and attempts to place it in the framework of endophyte research in general. It discusses the potential for harnessing the benefits of endophyte infection, whilst minimizing deleterious effects, through the use of elite endophyte strains which have been isolated from naturally occurring grasses, or modified by the techniques of genetic engineering. It concludes by identifying a number of significant areas which require further research for us to fully understand the plant-fungus interaction and its effects on pasture systems.

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