scholarly journals Comparison of inta-articular hyaluronic acid injections and mud-pack therapy in the treatment of knee osteoarthritis

2010 ◽  
Vol 44 (1) ◽  
pp. 42-47 ◽  
Author(s):  
Bora Bostan
2007 ◽  
Vol 74 (1) ◽  
pp. 60-65 ◽  
Author(s):  
Deniz Evcik ◽  
Vural Kavuncu ◽  
Abdurrahman Yeter ◽  
İlknur Yigit

2011 ◽  
Vol 32 (5) ◽  
pp. 1235-1244 ◽  
Author(s):  
Gonca Güngen ◽  
Fusun Ardic ◽  
Gülin Fιndıkoğlu ◽  
Simin Rota

Rheumatology ◽  
2012 ◽  
Vol 52 (4) ◽  
pp. 659-668 ◽  
Author(s):  
L. Espejo-Antunez ◽  
M. A. Cardero-Duran ◽  
E. M. Garrido-Ardila ◽  
S. Torres-Piles ◽  
B. Caro-Puertolas

2019 ◽  
Vol 64 (6) ◽  
pp. 943-950 ◽  
Author(s):  
Márta Király ◽  
Eszter Kővári ◽  
Katalin Hodosi ◽  
Péter V. Bálint ◽  
Tamás Bender

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Antonio Fraioli ◽  
Gioacchino Mennuni ◽  
Mario Fontana ◽  
Silvia Nocchi ◽  
Fulvia Ceccarelli ◽  
...  

Background. Osteoarthritis (OA) is the most common musculoskeletal disease in the world. OA is the result of an inflammatory and degenerative process affecting the entire joint. Osteoarthritis, especially involving the knee, has a relevant socioeconomic impact in terms of drugs, hospital admissions, work absences, and temporary or permanent invalidity. Therapy of knee osteoarthritis is based on pharmacological and nonpharmacological measures.Methods. We conducted a systematic review of the studies published between 2002 and 2017 on spa therapy, mud-pack therapy, balneotherapy, and mud-bath therapy in the treatment of knee osteoarthritis in order to investigate the evidence of the efficacy of such treatment on pain, functional limitation, drug use, and quality of life. Overall, 35 studies were examined among which 12 were selected and included in the review if they are trial comparative. We have been able to illustrate the main results obtained in the individual studies and to elaborate these results in order to allow as much a unitary presentation as possible and hence an overall judgment.Results. Because the studies we reviewed differed markedly from one another in terms of the methods used, we were unable to conduct a quantitative analysis (meta-analysis) of pooled data from the 12 studies. For the purposes of the present review, we reevaluated the results of the different studies using the same statistical method, Student’st-test, which is used to compare the means of two frequency distributions. Among all the studies, the most relevant indexes used to measure effectiveness of spa therapy were improved including VAS, Lequesne, and WOMAC Score.Conclusions. The mud-pack therapy, balneotherapy, mud-bath therapy, and spa therapy have proved to be effective in the treatment and in the secondary prevention of knee osteoarthritis, by reducing pain, nonsteroidal anti-inflammatory drug consumption, and functional limitation and improving quality of life of affected patients.


2013 ◽  
Vol 33 (10) ◽  
pp. 2569-2576 ◽  
Author(s):  
Ildikó Katalin Tefner ◽  
Ramóna Gaál ◽  
András Koroknai ◽  
Adél Ráthonyi ◽  
Tamás Gáti ◽  
...  

2021 ◽  
pp. 036354652199801
Author(s):  
Michael R. Baria ◽  
W. Kelton Vasileff ◽  
James Borchers ◽  
Alex DiBartola ◽  
David C. Flanigan ◽  
...  

Background: Platelet-rich plasma (PRP) and hyaluronic acid (HA) are injectable treatments for knee osteoarthritis. The focus of previous studies has compared their efficacy against each other as monotherapy. However, a new trend of combining these 2 injections has emerged in an attempt to have a synergistic effect. Purpose: To systematically review the clinical literature examining the combined use of PRP + HA. Design: Systematic review. Methods: A systematic review was performed according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines using PubMed and Embase. The following search terms were used: knee osteoarthritis AND platelet rich plasma AND hyaluronic acid. The review was performed by 2 independent reviewers who applied the inclusion/exclusion criteria and independently extracted data, including methodologic scoring, PRP preparation technique, HA composition, and patient-reported outcomes (PROs). Results: A total of 431 articles were screened, 12 reviewed in full, and 8 included in the final analysis: 2 case series, 3 comparative, and 3 randomized studies. Average follow-up was 9 months. The modified Coleman Methodology Score was 38.13 ± 13.1 (mean ± SD). Combination therapy resulted in improved PROs in all studies. Of the comparative and randomized studies, 2 demonstrated that combination therapy was superior to HA alone. However, when PRP alone was used as the control arm (4 studies), combination therapy was not superior to PRP alone. Conclusion: Combination therapy with PRP + HA improves PROs and is superior to HA alone but is not superior to PRP alone.


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