scholarly journals Biomechanical responses of the cornea after small incision lenticule extraction (SMILE) refractive surgery based on a finite element model of the human eye

2021 ◽  
Vol 18 (4) ◽  
pp. 4212-4225
Author(s):  
Yinyu Song ◽  
◽  
Lihua Fang ◽  
Qinyue Zhu ◽  
Ruirui Du ◽  
...  
Keyword(s):  
Finite Element ◽  
Finite Element Model ◽  
Refractive Surgery ◽  
Element Model ◽  
Small Incision Lenticule Extraction ◽  
Human Eye ◽  
Small Incision ◽  
Biomechanical Responses ◽  
Lenticule Extraction

SIMULATING THE EFFECTS OF ELEVATED INTRAOCULAR PRESSURE ON OCULAR STRUCTURES USING A GLOBAL FINITE ELEMENT MODEL OF THE HUMAN EYE

2017 ◽  
Vol 17 (02) ◽  
pp. 1750038 ◽  
Author(s):  
PEISHAN DAI ◽  
YALI ZHAO ◽  
HANWEI SHENG ◽  
LING LI ◽  
JING WU ◽  
...  
Keyword(s):  
Finite Element ◽  
Intraocular Pressure ◽  
Element Model ◽  
Global Model ◽  
Eye Model ◽  
Human Eye ◽  
Anterior Eye Segment ◽  
Elevated Intraocular Pressure ◽  
Biomechanical Responses ◽  
Iop Elevation

Elevated intraocular pressure (IOP) may be the primary risk factor to the development of glaucoma. Finite element (FE) modeling is commonly considered as an effective method to quantitatively analyze pathogenesis of glaucoma. Recent researches focus on establishing partial human eye models. A refined global human eye model was developed using ANSYS software to investigate the correlation between IOP elevation and biomechanical responses. First, the pressure transferring process according to IOP elevation in the whole eye was analyzed to simulate the effects of IOP elevation on glaucoma. Then, the biomechanical responses of the anterior eye segment under various pressure differences between the anterior and posterior chambers (AC and PC) were analyzed to simulate posterior nonadhesion of iris and posterior synechia. This global eye model not only simulated the responses of elevated IOP on ocular structures, but also revealed the process of pressure transferring among each tissue from the anterior eye segment to the optic nerve head (ONH) region. The local mechanical characteristics of the ocular structures obtained from the global model agreed with previous findings. This global model may shed light on the studies of multifactorial glaucoma.

FINITE ELEMENT ANALYSIS OF THE MECHANICAL CHARACTERISTICS OF GLAUCOMA

2016 ◽  
Vol 16 (04) ◽  
pp. 1650060 ◽  
Author(s):  
PEISHAN DAI ◽  
HAN HAN ◽  
YALI ZHAO ◽  
MIN FAN
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Optic Nerve ◽  
Finite Element Model ◽  
Mechanical Characteristics ◽  
Element Model ◽  
Finite Element Method Result ◽  
Element Analysis ◽  
Human Eye ◽  
Geometry Model

Purpose: Construct a finite element model of the human eye to quantitatively analyze the mechanical characteristics of the human eye, especially the glaucoma damage process of the optic nerve head (ONH). Method: First, the geometry model of the human eye with nonuniform thickness was established based on a reasonable hypothesis and assumptions. Because the ONH is an important factor for glaucoma, we refine the structure of the ONH with lamina cribrosa. Then, mesh division was applied for finite element analysis. To simplify the complexity of the analysis, the materials of the model were assumed to be isotropic linear elastic materials, and physical properties such as Young’s modulus and Poisson’s ratio were set according to published literature. Next, proper constraints and loads were applied to the model and solved with a finite element method. Result: A finite element model of the human eye was created to simulate the mechanical characteristics of the eye structures under high intraocular pressure (IOP). The ONH depressed 1.057[Formula: see text]mm under 0.009[Formula: see text]MPa pressure to simulate high IOP. Conclusion: The constructed model is able to quantitatively simulate excavation of the optic disc and damage of the optic nerve. The result proved Houcheng Liang’s hypothesis about the ONH damage mechanism in glaucoma.

Corneal Sensation After Corneal Refractive Surgery with Small Incision Lenticule Extraction

2013 ◽  
Vol 90 (10) ◽  
pp. 1040-1047 ◽  
Author(s):  
Ahmet Demirok ◽  
Engin Bilge Ozgurhan ◽  
Alper Agca ◽  
Necip Kara ◽  
Ercument Bozkurt ◽  
...  
Keyword(s):  
Refractive Surgery ◽  
Small Incision Lenticule Extraction ◽  
Corneal Sensation ◽  
Small Incision ◽  
Corneal Refractive Surgery ◽  
Lenticule Extraction
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