scholarly journals Modelling the human immune response mechanisms to mycobacterium tuberculosis infection in the lungs

2006 ◽  
Vol 3 (4) ◽  
pp. 661-682 ◽  
Keyword(s):  
Immune Response ◽  
Mycobacterium Tuberculosis ◽  
Tuberculosis Infection ◽  
Mycobacterium Tuberculosis Infection ◽  
Human Immune Response ◽  
Human Immune

scholarly journals Immune Response toward Mycobacterium Tuberculosis Infection

2020 ◽  
Vol 2 (2) ◽  
pp. 77-87
Author(s):  
Abdi Dzul Ikram Hasanuddin ◽  
Nanang Roswita ◽  
Ivan Virnanda Amu
Keyword(s):  
Immune Response ◽  
Mycobacterium Tuberculosis ◽  
Immune Responses ◽  
Tuberculosis Infection ◽  
Mycobacterium Tuberculosis Infection ◽  
Adaptive Immune ◽  
Human Immune Response ◽  
Exogenous Factors ◽  
Human Immune ◽  
Microfold Cells

Understanding the human immune response toward Mycobacterium tuberculosis infection is important for controlling its infection. Its transmission through the air consists of "droplets nuclei" containing TB bacilli. After initial infection, the human body will provide diverse immune responses and will determine different clinico-histopathologic finding. This response starts from innate immunity that consists of phagocytosis by distal alveolar macrophages or nasal microfold cells, then will be continued by dendritic cells to be transferred to mediastinal lymph nodes to induced adaptive immune responses. This response is mediated by cells through IFN- γ signaling which will enhance phagocytosis. If this response is effective, there will be a latent infection with an initial histopathological finding of caseosa granulomas and predominantly followed by chronic granulomas. In a few cases, it can be reactivated via the IL-10 activation pathway and exogenous factors, it will induce a great adaptive immune reaction and provide more severe clinico-histopathological manifestation. The existence of the human body's immune response to Mycobacterium tuberculosis, etiher innate or adaptive immunity will determine the clinical course and pathology that will occur.

scholarly journals Deletion of N-acetylmuramyl-L-alanine amidases alters the host immune response to Mycobacterium tuberculosis infection

Virulence ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 1227-1238
Author(s):  
Nathan Scott Kieswetter ◽  
Mumin Ozturk ◽  
Shelby-Sara Jones ◽  
Sibusiso Senzani ◽  
Melissa Dalcina Chengalroyen ◽  
...  
Keyword(s):  
Immune Response ◽  
Mycobacterium Tuberculosis ◽  
Host Immune Response ◽  
Tuberculosis Infection ◽  
Mycobacterium Tuberculosis Infection

scholarly journals Immune Response to Mycobacterium tuberculosis Infection in the Parietal Pleura of Patients with Tuberculous Pleurisy

PLoS ONE ◽  
2011 ◽  
Vol 6 (7) ◽  
pp. e22637 ◽  
Author(s):  
Gaetano Caramori ◽  
Lisa Lasagna ◽  
Angelo G. Casalini ◽  
Ian M. Adcock ◽  
Paolo Casolari ◽  
...  
Keyword(s):  
Immune Response ◽  
Mycobacterium Tuberculosis ◽  
Tuberculosis Infection ◽  
Parietal Pleura ◽  
Mycobacterium Tuberculosis Infection ◽  
Tuberculous Pleurisy

The Immune Response to Toxocariasis Does Not Modify Susceptibility to Mycobacterium tuberculosis Infection in BALB/c Mice

2007 ◽  
Vol 77 (4) ◽  
pp. 691-698 ◽  
Author(s):  
Fabiani Gai Frantz ◽  
Walter Miguel Turato ◽  
Rogério Silva Rosada ◽  
Célio Lopes Silva ◽  
Lúcia Helena Faccioli ◽  
...  
Keyword(s):  
Immune Response ◽  
Mycobacterium Tuberculosis ◽  
Tuberculosis Infection ◽  
Mycobacterium Tuberculosis Infection

scholarly journals Erratum for Araujo et al., Evaluation of Gamma Interferon Immune Response Elicited by the Newly Constructed PstS-1(285-374):CFP10 Fusion Protein To Detect Mycobacterium tuberculosis Infection

2014 ◽  
Vol 21 (11) ◽  
pp. 1600-1600
Author(s):  
Leonardo Silva de Araujo ◽  
Fernanda Carvalho de Queiroz Mello ◽  
Nidai de Bárbara Moreira da Silva ◽  
Janaina Aparecida Medeiros Leung ◽  
Silvia Maria Almeida Machado ◽  
...  
Keyword(s):  
Immune Response ◽  
Mycobacterium Tuberculosis ◽  
Fusion Protein ◽  
Gamma Interferon ◽  
Tuberculosis Infection ◽  
Mycobacterium Tuberculosis Infection
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