CRISPR engineering cardiometabolic disease models using human iPSC

Cindy E. McKinney;  ; Katherine M. Baumgarner

doi:10.3934/celltissue.2018.3.185

CRISPR engineering cardiometabolic disease models using human iPSC

AIMS Cell and Tissue Engineering ◽

10.3934/celltissue.2018.3.185 ◽

2018 ◽

Vol 2 (3) ◽

pp. 185-202

Author(s):

Cindy E. McKinney ◽

◽

Katherine M. Baumgarner

Keyword(s):

Cardiometabolic Disease ◽

Disease Models ◽

Human Ipsc

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Generating Late-Onset Human iPSC-Based Disease Models by Inducing Neuronal Age-Related Phenotypes through Telomerase Manipulation

Cell Reports ◽

10.1016/j.celrep.2016.09.062 ◽

2016 ◽

Vol 17 (4) ◽

pp. 1184-1192 ◽

Cited By ~ 59

Author(s):

Elsa Vera ◽

Nazario Bosco ◽

Lorenz Studer

Keyword(s):

Late Onset ◽

Disease Models ◽

Age Related ◽

Human Ipsc

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Drug Discovery Using Human iPSC Based Disease Models and Functional Hepatic Cells

Stem Cells and Cancer Stem Cells, Volume 10 ◽

10.1007/978-94-007-6262-6_9 ◽

2013 ◽

pp. 95-103

Author(s):

Su Mi Choi ◽

Yonghak Kim ◽

Yoon-Young Jang

Keyword(s):

Drug Discovery ◽

Disease Models ◽

Hepatic Cells ◽

Human Ipsc

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Changes in metabotropic glutamate receptor expression in the basal ganglia of Parkinson's disease models

Neuroscience Research ◽

10.1016/s0168-0102(00)81571-0 ◽

2000 ◽

Vol 38 ◽

pp. S121

Author(s):

M Takada

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Basal Ganglia ◽

Glutamate Receptor ◽

Metabotropic Glutamate Receptor ◽

Receptor Expression ◽

Disease Models ◽

Metabotropic Glutamate

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Establishment of Human Cellular Disease Models for Wilson Disease

Case Medical Research ◽

10.31525/ct1-nct03867526 ◽

2019 ◽

Author(s):

Keyword(s):

Wilson Disease ◽

Disease Models

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Faculty Opinions recommendation of Endocannabinoid-mediated rescue of striatal LTD and motor deficits in Parkinson's disease models.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1067031.519982 ◽

2007 ◽

Author(s):

Michele A Basso

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Motor Deficits ◽

Disease Models

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Faculty Opinions recommendation of Expression profiling of Huntington's disease models suggests that brain-derived neurotrophic factor depletion plays a major role in striatal degeneration.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1092788.547713 ◽

2007 ◽

Author(s):

Allan Tobin

Keyword(s):

Huntington's Disease ◽

Huntington’S Disease ◽

Neurotrophic Factor ◽

Expression Profiling ◽

Brain Derived Neurotrophic Factor ◽

Disease Models ◽

Striatal Degeneration

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Faculty Opinions recommendation of Reversal of long-term dendritic spine alterations in Alzheimer disease models.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1168191.630333 ◽

2009 ◽

Author(s):

Frank LaFerla

Keyword(s):

Alzheimer Disease ◽

Dendritic Spine ◽

Disease Models

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Faculty Opinions recommendation of Systematic discovery of nonobvious human disease models through orthologous phenotypes.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.2687956.2820055 ◽

2010 ◽

Author(s):

Ian Dunham

Keyword(s):

Human Disease ◽

Disease Models

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Faculty Opinions recommendation of Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.5008960.4940058 ◽

2010 ◽

Author(s):

George Perry

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Disease Models ◽

Sodium Selenate ◽

Tau Pathology ◽

Functional Deficits

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Faculty Opinions recommendation of Direct production of mouse disease models by embryo microinjection of TALENs and oligodeoxynucleotides.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717989823.793475567 ◽

2013 ◽

Author(s):

Lily Jan ◽

Shaohua Xiao

Keyword(s):

Disease Models ◽

Direct Production

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