Toxic Effects of Various Dietary Levels of Combined Cadmium Chloride and Zinc Chloride on Male Wistar Rats

2010 ◽  
Vol 6 (1) ◽  
pp. 76-81 ◽  
Author(s):  
N.H.A. Rhman ◽  
A.O. Bakhiet ◽  
S.E.I. Adam
Keyword(s):  
Zinc Chloride ◽  
Cadmium Chloride ◽  
Wistar Rats ◽  
Toxic Effects ◽  
Male Wistar Rats

scholarly journals Protective effect of antioxidant rich aqueous curry leaf ( Murraya koenigii ) extract against gastro-toxic effects of piroxicam in male Wistar rats

2014 ◽  
Vol 1 ◽  
pp. 987-1003 ◽  
Author(s):  
Syed Benazir Firdaus ◽  
Debosree Ghosh ◽  
Aindrila Chattyopadhyay ◽  
Mousumi Dutta ◽  
Sudeshna Paul ◽  
...  
Keyword(s):  
Protective Effect ◽  
Wistar Rats ◽  
Toxic Effects ◽  
Murraya Koenigii ◽  
Male Wistar Rats

scholarly journals Kigelia Africana Fruits' Extracts anti Hepato-Toxic Effects on Male Wistar Rats Liver Destruction Induced by CCL4

2013 ◽  
Vol 5 (1) ◽  
pp. 26-32 ◽  
Author(s):  
Shama Shama ◽  
I.Y. Adam ◽  
Marwa Marwa ◽  
I. Abd Alhameed
Keyword(s):  
Wistar Rats ◽  
Toxic Effects ◽  
Male Wistar Rats

A Study of Toxic Effects of Heavy Metal Contaminants from Sludge-Supplemented Diets on Male Wistar Rats

1999 ◽  
Vol 42 (2) ◽  
pp. 163-170 ◽  
Author(s):  
Shomesubra Bag ◽  
Tasnim Vora ◽  
Runa Ghatak ◽  
Irani Nilufer ◽  
Denness D'Mello ◽  
...  
Keyword(s):  
Heavy Metal ◽  
Wistar Rats ◽  
Toxic Effects ◽  
Metal Contaminants ◽  
Male Wistar Rats ◽  
Heavy Metal Contaminants

Effect of quercetin on cadmium chloride-induced impairments in sexual behaviour and steroidogenesis in male Wistar rats

Andrologia ◽  
2017 ◽  
Vol 50 (2) ◽  
pp. e12866 ◽  
Author(s):  
G. A. Ujah ◽  
V. U. Nna ◽  
M. I. Agah ◽  
L. O. Omue ◽  
C. B. Leku ◽  
...  
Keyword(s):  
Sexual Behaviour ◽  
Cadmium Chloride ◽  
Wistar Rats ◽  
Male Wistar Rats

scholarly journals Effects of Garcinia hydroxybiflavanonol-1 (GB1) isolated from Garcinia kola Heckel (Guttiferae) seeds on reproductive toxicity induced with cadmium chloride (CdCl2) in male Wistar rats

2020 ◽  
Vol 4 (1) ◽  
pp. 21-30
Author(s):  
E. A. Uwagie-Ero ◽  
C. O. Nwaehujor
Keyword(s):  
Cadmium Chloride ◽  
Wistar Rats ◽  
Sperm Count ◽  
Cadmium Toxicity ◽  
Reproductive Toxicity ◽  
Seminiferous Tubules ◽  
Garcinia Kola ◽  
Male Wistar Rats ◽  
Garcinia Kola Heckel ◽  
Group B

To examine the effects of Garcinia hydroxybiflavanonol-1 (GB1) isolated from seeds of Garcinia kola Heckel (Guttiferae) on reproductive toxicity induced with cadmium chloride (CdCl2) in male Wistar rats. Rats were randomly assigned to Groups 1 to 3 (n = 12) as follows; A: control, B: CdCl2 only group, C: CdCl2+GB1. Cadmium toxicity was induced by including 2.5 mg/kg of CdCl2 into the rats’ drinking water and GB1 was dissolved in 0.5 % Tween20 and administered per os daily for 90 days. Four (4) animals from each group was humanely euthanized every 30 days. The testes were exteriorized and sperm cells collected from the caudal epididymis for analysis and histology.The result showed accumulation of Cadmium (Cd) in the testes of Wistar rats and a significant decrease (p< 0.05) in sperm count and sperm motility in Group B compared to Groups A and C. There was also a significant increase (p< 0.05) in immotile sperm count, headless sperm count and sluggish sperm count in Group B. Histology results revealed that CdCl2 significantly reduced the volume of spermatozoa in the seminiferous tubules and resulted in reduced spermatogenesis observed, in reduced number of sperm counts and histology. Amelioration with GB1 restored the testicles to normal spermatogenic activities after 90 days of treatment.

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