Changes of Hair Diameter after Treatment of Androgenic Alopecia; the First Case-control Study

2014 ◽  
Vol 14 (2) ◽  
pp. 97-100
Author(s):  
Effat Khodaeiani ◽  
Shahla Babaeinejad . ◽  
Mahsa Jamshidi Asl . ◽  
Elham Razzagh Karimi . ◽  
Daniel F. Fouladi . ◽  
...  
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Androgenic Alopecia ◽  
First Case ◽  
Control Study ◽  
Hair Diameter

scholarly journals Risk factors for sporadic Campylobacter infection: an all-Ireland case-control study

2009 ◽  
Vol 14 (7) ◽  
Author(s):  
K Danis ◽  
M Di Renzi ◽  
W O’Neill ◽  
B Smyth ◽  
P McKeown ◽  
...  
Keyword(s):  
Risk Factors ◽  
Case Control Study ◽  
Population Attributable Fraction ◽  
Case Control ◽  
Control Measures ◽  
Safety Education ◽  
First Case ◽  
The Republic ◽  
Campylobacter Infection ◽  
Control Study

We report the findings of the first case-control study conducted in both the Republic of Ireland and Northern Ireland to determine risk factors for sporadic Campylobacter infections. A total of 197 cases and 296 case-nominated controls matched for age, were included. Based on Population Attributable Fraction (PAF), the most important risk factors were consuming chicken [adjusted matched (am) OR 6.8; 95%CI 2.1-21.9], consuming lettuce (amOR 3.3; 95%CI 1.5-7.1) and eating in takeaways (amOR=3.1; 95%CI 1.4-6.6). Contact with sheep (amOR=11; 95%CI 1.6-78), peptic ulcer (amOR=19; 95%CI 3.8-93.7), hiatus hernia (amOR=20.3; 95%CI 2.3-183.3), lower bowel problems (amOR=4.5; 95%CI 1.2-16.8) were also independently associated with infection. Mains water supply showed protective effect (amOR=0.2; 95 CI 0.1-0.9). The findings highlight the continued need for consumer food safety education and further control measures throughout the food chain on the island of Ireland.

scholarly journals MTHFR and F5 genetic variations have association with preeclampsia in Pakistani patients: a case control study

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Feriha Fatima Khidri ◽  
Yar Muhammad Waryah ◽  
Faiza Kamran Ali ◽  
Hina Shaikh ◽  
Ikram Din Ujjan ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Case Control Study ◽  
Protective Role ◽  
Case Control ◽  
Amplification Refractory Mutation System ◽  
World Population ◽  
Single Nucleotide Variants ◽  
First Case ◽  
Control Study

Abstract Background To study the role of single nucleotide variants (SNVs) of genes related to preeclampsia in Pakistani pregnant women. Methods After ethical approval and getting informed consent; 250 pregnant women were enrolled and equally divided into two groups (125 preeclamptic cases and 125 normotensive pregnant women). Demographic details and medical history were recorded, and 10 ml blood sample was obtained for DNA extraction. The tetra-primer amplification refractory mutation system (ARMS) assays were developed for assessing the variants of three preeclampsia related genes; F5, MTHFR and VEGFA. An association of six SNVs; F5:c.1601G > A (rs6025), F5:c.6665A > G (rs6027), MTHFR: c.665C > T (rs1801133), MTHFR: c.1286A > C (rs1801131), VEGFA: c.-2055A > C (rs699947) and VEGFA: c.*237C > T (rs3025039) with preeclampsia was determined by using different genetic models. Results Genotyping of the SNVs revealed that patients with MTHFR:c.665C > T, have increased susceptibility to preeclampsia (CT versus CC/TT: OR = 2.79, 95% CI = 1.18–6.59; P* = 0.046 and CT/TT vs CC: OR = 2.91, 95% CI = 1.29–6.57; P* = 0.0497, in overdominant and dominant models, respectively), whereas F5:c.6665A > G, (A/G vs AA/GG: OR = 0.42, 95% CI = 0.21–0.84; P* = 0.038 in overdominant model) and MTHFR:c.1286A > C, (CC versus AA: OR = 0.36, 95% CI = 0.18–0.72; P* = 0.0392 in codominant model) have significantly decreased risk for preeclampsia. F5:c.1601G > A, VEGFA: c.-2055A > C and VEGFA: c.*237C > T variants revealed no relationship with the disease. Conclusion This is the first case control study describing the protective role of F5:c.6665A > G against preeclampsia in any world population. In addition, the present study confirmed the association and role of MTHFR gene variations in the development of preeclampsia in Pakistani patients. Further genetic studies may be required to better understand the complex genetic mechanism of SNVs in preeclampsia related genes in pregnant women.

HIPEC in ovarian cancer: The first case control study in Mexican patients with 10-year follow-up

2020 ◽  
Vol 159 ◽  
pp. 152
Author(s):  
J.M. Medina ◽  
A.B. Gonzalez-Valdes ◽  
F. Morales-Vasquez ◽  
F. Rivera-Buendia ◽  
H.N. López-Basave ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Case Control Study ◽  
Case Control ◽  
First Case ◽  
Control Study ◽  
Mexican Patients

scholarly journals Traditional and Commercial Alcohols as Risk Factors for Esophageal Cancer in Tanzania

2020 ◽  
Vol 6 (Supplement_1) ◽  
pp. 36-36
Author(s):  
Alexandra Keir ◽  
Geoffrey Buckle ◽  
Larry Akoko ◽  
William Mgisha ◽  
Julius Mwaiselage ◽  
...  
Keyword(s):  
Risk Factors ◽  
Esophageal Cancer ◽  
Case Control Study ◽  
Conditional Logistic Regression ◽  
Secondary Analysis ◽  
Case Control ◽  
First Case ◽  
Increased Risk ◽  
Context Specific ◽  
Control Study

PURPOSE Esophageal cancer (EC) is one of the most common cancers in East Africa; however, risk factors that underly the high incidence in this region are not well understood. We aimed to investigate the association between exposure to specific alcohol subtypes and EC in Tanzania. METHODS We performed a secondary analysis of data from a hospital-based, case-control study conducted at Muhimbili National Hospital and Ocean Road Cancer Institute in Dar es Salaam, Tanzania. Cases of EC were identified between 2014 and 2016. Hospital controls were identified from patients with nonmalignant conditions and matched 1:1 for gender and age (± 10 years). Interviews were conducted using a survey with culturally relevant and context-specific questions on alcohol and smoking exposure. Conditional logistic regression analyses were applied to evaluate specific associations of potential exposures and EC. RESULTS A total of 473 EC cases and 473 controls were enrolled. Alcohol consumption was reported in 61% and 64% of cases and controls, respectively. Neither ‘current use of alcohol (any type)’, nor ‘ever use’ were associated with EC; however, local brew consumption was associated with increased EC risk (odds ratio [OR], 2.01; 95% CI, 1.53 to 2.66; P < .01). Increased risk was observed with consumption of gongo (OR, 2.91), komoni (OR, 2.41), wanzuki (OR, 2.40), kindi (OR, 3.13), and kangara (OR, 2.86). Smoking increased EC risk; however, it did not significantly modify the association between EC and alcohol subtypes. CONCLUSION This is the first case-control study to report a detailed analysis of alcohol exposures as a potential risk factor for EC in Tanzania. Although combined measures of alcohol use were not found to be associated with EC, several types of locally brewed alcohols emerged as risk factors. Additional research is needed to investigate these findings and examine the carcinogenic role of ingredients and/or contaminants, as well as any interactions with other putative risk factors in this region.

scholarly journals 360. A Case Control Study of COVID-19 in Patients with End Stage Renal Disease (ESRD)

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S250-S250
Author(s):  
Su Lin Lim ◽  
Kok Hoe Chan ◽  
Sudha Lagudu ◽  
Maria Szabela ◽  
Jihad Slim
Keyword(s):  
Clinical Outcome ◽  
Case Control Study ◽  
Case Control ◽  
Retrospective Case ◽  
Global Pandemic ◽  
First Case ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients ◽  
Control Study

Abstract Background COVID-19 is a major global pandemic. Since the first case reported in Wuhan, China, COVID-19 has spread across the globe with more than 7.6 million individuals affected worldwide. Several studies have tried to investigate the risk factors for mortality but there has bot been a definitive study in patients with ESRD. Herein, we aimed to investigate whether ESRD is associated with mortality as compared to age, gender and comorbidities matched cohorts. Methods A retrospective case control study was performed on patients 18-year-old with confirmed SARS-CoV-2 admitted to our hospital during the study period (03/15/2020 to 05/15/2020). Demographic, characteristics and clinical outcome were retrieved and reviewed. We found 39 ESRD patients, we matched them for 5 variables: Age, gender, diabetes mellitus (DM), hypertension (HTN), and body mass index (BMI). Age was stratified into 3 groups (&lt; 30, 30 to 60, &gt;60), history of DM and HTN were defined by reviewing the admission medications, and BMI was divided into 2 categories (&lt; 30 and 30 kg/m2). The primary endpoint was percentage of inpatient mortality. Results We had 39 ESRD patients with COVID-19 out of the 400 patients admitted during the study period with known clinical outcome. Nineteen patients (49%) were between 30 to 60 years old while the rest (51%) were older than 60 years old. As for gender, 25 (64%) were males and 14 (36%) females. Additional comorbidities were present in 38 patients with hypertension (92%) being the most common, followed by DM (64%) and BMI &gt;30 kg/m2 (49%). With the 5 variables, we were able to match with 177 controls. Nineteen individuals expired out of the 39 ESRD patients (49%), as compared to 46 patients from the 177 matched cohort (26%) (z-score 2.80, p=0.0051; odds ratio [OR], 2.71; 95% confidence interval [CI], 1.28–5.41). Conclusion Our results suggest that ESRD patients is an independent risk factor for increased mortality in patients with COVID 19 disease. Larger prospective studies will need to confirm this finding and try to find ways to mitigate this very high mortality in this vulnerable population. Disclosures Jihad Slim, MD, Abbvie (Speaker’s Bureau)Gilead (Speaker’s Bureau)Jansen (Speaker’s Bureau)Merck (Speaker’s Bureau)ViiV (Speaker’s Bureau)

scholarly journals First case-control study of zoonotic brucellosis in Gafsa district, Southwest Tunisia

One Health ◽  
2018 ◽  
Vol 5 ◽  
pp. 21-26 ◽  
Author(s):  
Médiha Khamassi Khbou ◽  
Samaher Htira ◽  
Kaouther Harabech ◽  
M’hammed Benzarti
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
First Case ◽  
Control Study

scholarly journals ABO Blood Groups in Oral Cancer: A First Case-Control Study in a Defined Group of Iranian Patients

2014 ◽  
Vol 15 (3) ◽  
pp. 1415-1418 ◽  
Author(s):  
Hamed Mortazavi ◽  
Shima Hajian ◽  
Elnaz Fadavi ◽  
Siamak Sabour ◽  
Maryam Baharvand ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Blood Groups ◽  
Abo Blood Groups ◽  
First Case ◽  
Control Study ◽  
Iranian Patients

scholarly journals Human T-Lymphotropic Virus Type I (HTLV-1) Infection among Iranian Blood Donors: First Case-Control Study on the Risk Factors

Viruses ◽  
2015 ◽  
Vol 7 (11) ◽  
pp. 5736-5745 ◽  
Author(s):  
Mohammad Hedayati-Moghaddam ◽  
Farahnaz Tehranian ◽  
Maryam Bayati
Keyword(s):  
Risk Factors ◽  
Virus Type ◽  
Blood Donors ◽  
Case Control Study ◽  
Case Control ◽  
Type I ◽  
T Lymphotropic Virus ◽  
First Case ◽  
Control Study

scholarly journals Case-Control Study of Risk Factors for Sporadic Giardiasis and Parasite Assemblages in North West England

2015 ◽  
Vol 53 (10) ◽  
pp. 3133-3140 ◽  
Author(s):  
Corrado Minetti ◽  
Kenneth Lamden ◽  
Caroline Durband ◽  
John Cheesbrough ◽  
Katherine Platt ◽  
...  
Keyword(s):  
Risk Factors ◽  
Case Control Study ◽  
Giardia Duodenalis ◽  
Epidemiological Data ◽  
Case Control ◽  
Content Type ◽  
North West ◽  
First Case ◽  
Infectious Gastroenteritis ◽  
Control Study

Giardia duodenalisis a major cause of infectious gastroenteritis worldwide, and it is diversified into eight genetic assemblages (A to H), which are distinguishable only by molecular typing. There is some evidence that the assemblages infecting humans (assemblages A and B) may have different transmission routes, but systematically acquired data, combining epidemiological and molecular findings, are required. We undertook a case-control study withGiardiagenotyping in North West England, to determine general and parasite assemblage-specific risk factors. For people without a history of foreign travel, swimming in swimming pools and changing diapers were the most important risk factors for the disease. People infected with assemblage B reported a greater number of symptoms and higher frequencies of vomiting, abdominal pain, swollen stomach, and loss of appetite, compared with people infected with assemblage A. More importantly, keeping a dog was associated only with assemblage A infections, suggesting the presence of a potential zoonotic reservoir for this assemblage. This is the first case-control study to combine epidemiological data withGiardiagenotyping, and it shows the importance of integrating these two levels of information for better understanding of the epidemiology of this pathogen.

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