Influence of Tinospora cordifolia Root Extract Supplementation on Hematological and Serological Parameters of Male Mice Exposed to Aflatoxin B1

2011 ◽  
Vol 7 (5) ◽  
pp. 659-663 ◽  
Author(s):  
Veena Sharma ◽  
Rekha Gupta ◽  
Nidhi Mishra ◽  
Shatruhan Sharma
2013 ◽  
Vol 28 (4) ◽  
pp. 389-397
Author(s):  
Priyanka Sharma ◽  
Pradeep Goyal

The present study deals with the radiomodulatory influence of Tinospora cordifolia (Amrita) root extract on the peripheral blood of Swiss albino mice after 5.0 Gy gamma irradiation in the presence (experimental) or absence (control) of Tinospora cordifolia (75 mg/kg b.wt/day). The animals from different groups were necropsied and their blood collected on days 1, 3, 7, 15, and 30 postirradiation. A considerable decrease was recorded in the number of erythrocyte and total leucocyte counts, differential leucocytes, hemoglobin content, and hematocrit percentage in the irradiated control group, while a recovery pattern was recorded in experimental animals, however, without the attainment of normal levels up to the end of the experiment. Furthermore, Tinospora cordifolia root extract pretreatment significantly ameliorated radiation-induced elevation in cholesterol and lipid peroxidation levels, whereas, a decline in glutathione and total proteins concentration was noted.


2019 ◽  
Vol 186 ◽  
pp. 109697 ◽  
Author(s):  
Hongyuan Zhou ◽  
Jiaman Wang ◽  
Liang Ma ◽  
Lu Chen ◽  
Ting Guo ◽  
...  

2015 ◽  
Vol 06 (03) ◽  
pp. 326-331 ◽  
Author(s):  
Mahsa Hadipour Jahromy ◽  
Ahmad Jamshidi Mohajer ◽  
Leila Adibi ◽  
Shahrzad Khakpour

2020 ◽  
Vol 15 (3) ◽  
pp. 50-55
Author(s):  
S.B Adeyemi ◽  
A. I Afonja ◽  
M.B Odebisi-Omokanye ◽  
T.P Okor ◽  
A.A Lateef

An ethnobotanical investigation has revealed that the roots of Anthocliesta vogelii and stem bark of Tinospora cordifolia are used by indigenous people in the treatment of pile. This present study evaluated the antibacterial activity of the root and stem bark of Anthocliesta vogelii and Tinospora cordifolia respectively against the human pathogenic gram-negative bacteria Pseudomonas aeruginosa and Escherichia coli. The phytochemical composition of these two plants was also assayed. Graded concentrations of 25mg/ml, 50mg/ml, 100mg/ml and 200mg/ml of the respective crude extract were applied against the test organisms. The percentage yield of the ethanolic extract of T. cordifolia stem and A. vogelii root were 40.978% and 21.872% respectively with their phytochemical analysis revealing the presence of saponins, alkaloids, tannins, flavonoids, and glycosides, with steroids present in A. vogelii but absent in T. cordifolia. The antimicrobial effect of the ethanolic extracts of both plants on the two test bacteria was significant (P<0.05). However, the ethanolic root extract of A. vogelii showed higher inhibition against P. aeruginosa and E. coli than the ethanolic stem extract of T. cordifolia at concentrations of 50mg/ml, 100mg/ml and 200mg/ml, while both extracts did not have any inhibition on the test organisms at a concentration of 25mg/ml. The Minimum Inhibitory Concentrations (MICs) of the ethanolic extract of A. vogelii root on P. aeruginosa and E. coli were 50mg/ml and 100mg/ml respectively, while the MICs for the ethanolic extract of T. cordifolia stem on P. aeruginosa and E. coli was 50mg/ml respectively. Both plant extracts could not kill the test bacteria; hence, they are only bacteriostatic and not bactericidal against the test bacteria. Keywords: Anthocleista vogelii, Tinospora cordifolia, Bacterial, Bacteriostatic, Bactericidal


2017 ◽  
Vol 20 (2) ◽  
pp. 1-6
Author(s):  
Mohammad Kanedi ◽  
Sutyarso ◽  
Hendri Busman ◽  
Nuning Nurcahyani ◽  
Wiwit Nurkhasanah
Keyword(s):  

Sign in / Sign up

Export Citation Format

Share Document