Nutraceuticals: a goldmine but for whom?

2017 ◽  
Vol 13 (3) ◽  
pp. 121-126 ◽  
Author(s):  
K.H. McKeever

A whole new industry has grown up around dietary supplements that purportedly can, enhance exercise performance or enhance the recovery from exercise. Many of these new supplements are ‘functional foods’ or nutraceuticals that have active molecules or ingredients that purportedly can reduce inflammation, prevent oxidative stress or have other benefits for whatever may ails an equine athlete. The blitz of advertising that usually accompanies such miracle ergogenic (i.e. performance enhancing) products suggests that a great deal of scientific research has been published to support those claims. Unfortunately, the majority of new dietary supplements are being promoted with little or no scientific basis for the claims made on their labels or in the advertisements touting their benefits. In many cases, no research has been performed to demonstrate efficacy of these new expensive, avant-garde, dietary supplements in the horse. So how can we determine if a new supplement improves recovery from exercise or has potential to improve athletic capacity? The purpose of this review is to outline the important questions a horse owner, trainer, veterinarian, or regulator should ask before deciding it is ok (safety, legality) or even beneficial to feed a supplement to an athletic horse.

Antioxidants ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 191
Author(s):  
Junsei Taira

Many years of research have seen the investigation of natural antioxidants and dietary supplements as functional foods with the potential to prevent oxidative stress due to the scavenging of reactive oxygen species (ROS) and reactive nitrogen species (RNS) [...]


Antioxidants ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1116
Author(s):  
Omar Cauli

Cognitive impairment is one of the most deleterious effects of chemotherapy treatment in cancer patients, and this problem sometimes remains even after chemotherapy ends. Common classes of chemotherapy-based regimens such as anthracyclines, taxanes, and platinum derivatives can induce both oxidative stress in the blood and in the brain, and these effects can be reproduced in neuronal and glia cell cultures. In rodent models, both the acute and repeated administration of doxorubicin or adriamycin (anthracyclines) or cisplatin impairs cognitive functions, as shown by their diminished performance in different learning and memory behavioural tasks. Administration of compounds with strong antioxidant effects such as N-acetylcysteine, gamma-glutamyl cysteine ethyl ester, polydatin, caffeic acid phenethyl ester, and 2-mercaptoethane sulfonate sodium (MESNA) counteract both oxidative stress and cognitive alterations induced by chemotherapeutic drugs. These antioxidant molecules provide the scientific basis to design clinical trials in patients with the aim of reducing the oxidative stress and cognitive alterations, among other probable central nervous system changes, elicited by chemotherapy in cancer patients. In particular, N-acetylcysteine and MESNA are currently used in clinical settings and are therefore attracting scientific attention.


2004 ◽  
Vol 162 (5) ◽  
pp. 572-579 ◽  
Author(s):  
Jun Guan ◽  
X. Steven Wan ◽  
Zhaozong Zhou ◽  
Jeffrey Ware ◽  
Jeremiah J. Donahue ◽  
...  

Molecules ◽  
2021 ◽  
Vol 26 (5) ◽  
pp. 1306
Author(s):  
Diane Purcell-Meyerink ◽  
Michael A. Packer ◽  
Thomas T. Wheeler ◽  
Maria Hayes

Seaweeds have a long history of use as food, as flavouring agents, and find use in traditional folk medicine. Seaweed products range from food, feed, and dietary supplements to pharmaceuticals, and from bioenergy intermediates to materials. At present, 98% of the seaweed required by the seaweed industry is provided by five genera and only ten species. The two brown kelp seaweeds Laminaria digitata, a native Irish species, and Macrocystis pyrifera, a native New Zealand species, are not included in these eleven species, although they have been used as dietary supplements and as animal and fish feed. The properties associated with the polysaccharides and proteins from these two species have resulted in increased interest in them, enabling their use as functional foods. Improvements and optimisations in aquaculture methods and bioproduct extractions are essential to realise the commercial potential of these seaweeds. Recent advances in optimising these processes are outlined in this review, as well as potential future applications of L. digitata and, to a greater extent, M. pyrifera which, to date, has been predominately only wild-harvested. These include bio-refinery processing to produce ingredients for nutricosmetics, functional foods, cosmeceuticals, and bioplastics. Areas that currently limit the commercial potential of these two species are highlighted.


Author(s):  
Pacôme Kouadio N’Go ◽  
Lazare Tehoua ◽  
Eric-Kevin Gbouhoury Bolou ◽  
Aicha Salamentou Touré ◽  
Antoine Némé Tako

Aims: Adenia lobata (Jacq.) Engl. (Passifloraceae) is widely used in Ivorian traditional pharmacopeia to heal various chronic diseases, relieve headache and pain of gingiva inflammation, and facilitate labor. Here, we investigated the effects of hydroethanolic extract Adenia lobata (HEAL) on nociceptive pain and subsequent anxiety-like behavior. Materials and Methods: We used several experimental pain tests as the writhing, formalin and hot plate to evaluate both antinociceptive and anti-inflammatory actions of the extract. Anxiety related to nociception was tested with open field and elevated plus maze tests. Then, mice were sacrificed for assessing some oxidative stress markers.    Results: The extract of 30 mg/kg, p.o. reduced in the similar manner as reference peripheral drug salcylicacetic acid (ASA, 200 mg/kg, i.p.) the number of writhings induced by acid acetic. In both neurogenic and inflammatory phases of formalin test, the extract demonstrated an effective antinociceptive activity than ASA, but comparable to central analgesic tramadol (50 mg/kg, i.p). However, Adenia lobata reduced lesser thermal-induced pain than tramadol in hot plate test, but significantly compared to ASA. Furthermore, HEAL altered anxiety-like behavior in each case of the pain condition studied. Also, the extract showed the highest antioxidant activity by reduction oxide nitric (NO) and malondialdehyde (MDA), and increase non protein thiol (NP-SH) levels.     Conclusion: In conclusion, HEAL possesses antinociceptive and anti-inflammatory actions on peripheral and central mechanisms of pain. The phytochemicals components of the extract as alkaloids and flavonoids suggest to interact with the opioid system and combat the oxidative stress, respectively. Our findings provide scientific basis for the use of Adenia lobata in traditional medicine against pain and related diseases.


1998 ◽  
Vol 7 (2) ◽  
pp. 283-296 ◽  
Author(s):  
Hannu Korhonen ◽  
Anne Pihlanto-Leppälä ◽  
Pirjo Rantamäki ◽  
Tuomo Tupasela

Advances in processing technologies and the accumulation of scientific data on the functional and biological properties of whey components have contributed to the growing commercial valuation of cheese whey over the last decade. New membrane separation and chromatographic techniques have made it possible to fractionate and enrich various components of whey more efficiently than before. The specific properties of these components can now be examined in greater detail and new applications developed accordingly. The utilisation of cheese whey is evolving into a new industry producing a multitude of purified ingredients for numerous purposes. The most significant areas of R&D related to whey proteins include functional foods, the rheological properties of foodstuffs, and biopharmaceuticals.


eFood ◽  
2021 ◽  
Author(s):  
Lingjun Ma

In order to strengthen the international academic exchanges and cooperation, promote the development of phytochemical natural products, functional foods and related scientific research, 5th International Symposium on Phytochemicals in Medicine and Food (5-ISPMF) was successfully held as virtual and onsite model from August 25 to September 01, and October 18 to 20, 2021. 5-ISPMF was sponsored by the International Association of Dietetic Nutrition and Safety (IADNS), Phytochemical Society of Europe (PSE), and Phytochemical Society of Asia (PSA). It is organized by Nanchang University and University of Vigo. The Organizing Committee was led by Prof. Shaoping Nie (Nanchang University, China) and Prof. Jesús Simal Gándara (University of Vigo, Spain). 5-ISPMF brought together more than 730 delegates from 66 different countries and the foreigners out of China are more than 405.


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