Aerobic exercise produces changes in plasma IL-6 but not IL-1b in four-beat gaited horses

2015 ◽  
Vol 11 (3) ◽  
pp. 159-165 ◽  
Author(s):  
L.M.C. Ferreira ◽  
S.K.M. Melo ◽  
A.I.A. Diniz ◽  
S.G. Vaz ◽  
J.M.G. Abreu ◽  
...  
Keyword(s):  
Aerobic Exercise ◽  
Repeated Measures ◽  
Pearson Correlation ◽  
Nonesterified Fatty Acid ◽  
Simulation Test ◽  
Warm Up ◽  
Pearson Correlation Test ◽  
Gaited Horses ◽  
Medium Correlation ◽  
Energetic Metabolites

Exercise is an important stressor and is correlated with cytokine production in several tissues. There is little information about changes in interleukin (IL)-6 and IL-1b in four-beat gaited horses during a typical aerobic exercise challenge. The objective of this research was to characterise changes in plasma IL-6, IL-1b, cortisol and other blood biomarkers in four-beat gaited horses after a marcha simulation test. We subjected 12 fit horses (approximately 5 years old and 390 kg) to the marcha simulation test (MST) (i.e. a 10 min warm-up, 30 min at marcha and 15 min cool down). Blood samples were collected before the MST, immediately after the MST and 15 and 120 min after the MST (i.e. recovery). Results were analysed with One Way Repeated Measures ANOVA and a Tukey tests with P≤0.05 and Pearson correlation test. The highest value of plasma IL-6 was observed immediately after MST (6.85 pg/ml) (P≥0.05). IL-1 and cortisol did not change (P≥0.05). However, creatine kinase (CK) and aspartate aminotransferase, nonesterified fatty acid (NEFA), glycerol, total cholesterol and glucose were elevated immediately after the MST and at 15 min after the MST (P≤0.05). No change was observed in alanine aminotransferase and triglycerides (P>0.05). Medium correlation was observed between NEFA and glycerol (R=0.64) and glycerol and triglycerides (R=0.50). In conclusion, an increase in IL-6 immediately that occurred after marcha simulation test was associated with elevated concentrations of several energetic metabolites (NEFA, glycerol and glucose). This metabolic adaption may contributed to the horses’ performance during their typical aerobic exercise and was not associated with significant elevation in IL-1b, CK, and cortisol in healthy trained four-beat gaited horses.

Assessment of Peroxide in Saliva During and After At-home Bleaching With 10% Carbamide and Hydrogen Peroxide Gels: A Clinical Crossover Trial

2020 ◽  
Vol 45 (4) ◽  
pp. 368-376
Author(s):  
MC Mailart ◽  
PA Sakassegawa ◽  
CRG Torres ◽  
RM Palo ◽  
AB Borges
Keyword(s):  
Hydrogen Peroxide ◽  
Repeated Measures ◽  
Pearson Correlation ◽  
Salivary Flow ◽  
Toxic Dose ◽  
Repeated Measures Analysis ◽  
Significant Difference ◽  
Pearson Correlation Test ◽  
Mouth Rinsing ◽  
At Home

Clinical Relevance This study suggests that at-home bleaching systems are safe in relation to toxicity based on peroxide levels in saliva since the amount of peroxide potentially ingested is much lower than the estimated toxic dose. SUMMARY Objectives: This study evaluated the presence of peroxide in saliva using at-home bleaching systems containing hydrogen peroxide (HP) and carbamide peroxide (CP) with a prefilled tray (PT) or conventional tray (CT). Methods and Materials: Participants received bleaching treatments after the sequence randomization (n=10): PT-HP/OpalescenceGo10%; CT-HP/WhiteClass10%; and CT-CP/OpalescencePF10%. Saliva was collected at the following times: baseline; at 1, 5, 15, and 30 minutes after administration; and at 3, 5, and 8 minutes after the tray was removed. Colorimetric analysis using analytic spectrophotometry was performed. The salivary flow (SF) was monitored during use of trays. Data about peroxide concentration (PC) were submitted to repeated-measures analysis of variance and Tukey tests (5%), and toxic dose was calculated based on body weight. The relation between SF and PC was verified with the Pearson correlation test. Results: There was a significant difference for bleaching (p=0.0001) and time (p=0.0003) but not for interaction (p=0.3121). PC was lower for CT-CP in relation to PT-HP and CT-HP. After tray removal, expectoration, of the remaining gel, and mouth rinsing, no peroxide was detected in saliva. Correlation between SF and PC was considered weak (r=0.3379). The overall mean SF was 50.44% during tray use. In general, PC in saliva was 68.72% lower than the estimated toxic dose (0.26 mg/kg/day) considering all the bleaching systems. Conclusions: Higher peroxide levels were detected in saliva with 10% HP gels. Nevertheless, they were below estimated toxic dose and were considered safe in relation to toxicity.

scholarly journals Are Saliva Tests Important in the Prediction of Carious Disease?

2021 ◽  
Vol 11 (13) ◽  
pp. 5932
Author(s):  
Daniela Luminita Ichim ◽  
Liliana Sachelarie ◽  
Alexandra Burlui
Keyword(s):  
Health Promotion ◽  
Pearson Correlation ◽  
Coefficient Of Determination ◽  
Data Series ◽  
Study Group ◽  
Complex Phenomenon ◽  
Oral Health Promotion ◽  
Group 4 ◽  
Carious Lesions ◽  
Pearson Correlation Test

(1) Background: The appearance and progression of carious lesions represent a complex phenomenon of interactions of microbial factors (the action of bacteria on the tooth), of the factors related to the host, to the diet, and to the time factor. Which hasan influence on the rate of microbismof the oral cavity on the installation of carious disease? (2) Methods: In order to correctly assess the cariogenic risk of an individual, it is recommended to perform twoor more tests based on different principles (microbiological, clinical, epidemiological). The representative data series for the investigation were analyzed statistically and by applying the Pearson correlation test considering the coefficient of determination R for all pairs of data series. (3) Results: Salivary tests played animportant role in establishing control sessions, in carrying out prophylactic caries therapy, and establishing prognosis. The existence of a statistical associationwas confirmed between the prevalence of dental caries and the results of salivary tests for the study group. (4) Conclusions: The results of the saliva tests can be used in oral health promotion.

Dentate nucleus signal intensity changes on T1-weighted MRI after repeated administrations of linear and macrocyclic gadolinium-based contrast agents: a pediatric intraindividual case-control study

2021 ◽  
pp. 028418512110188
Author(s):  
Kerem Ozturk ◽  
David Nascene
Keyword(s):  
Repeated Measures ◽  
Signal Intensity ◽  
Dentate Nucleus ◽  
Pearson Correlation ◽  
Gadopentetate Dimeglumine ◽  
Control Groups ◽  
Significant Difference ◽  
Intensity Changes ◽  
Cerebellar Peduncle ◽  
Pediatric Brain

Background An association between consecutive administrations of macrocyclic gadolinium-based contrast agent (mcGBCA) gadobutrol and linear (L)-GBCA gadopentetate dimeglumine and gadolinium retention in the pediatric brain remains incompletely understood. Purpose To compare signal intensity (SI) changes in the dentate nucleus (DN) on unenhanced T1-weighted imaging (T1WI) in children who obtained mcGBCA gadobutrol with those who had previously received L-GBCA gadopentetate dimeglumine. Material and Methods This retrospective study included 27 children who received L-GBCA gadopentetate dimeglumine followed by mcGBCA gadobutrol and two different control groups matched for age and sex for both periods, each involving 27 individuals with no GBCA administration from January 2010 to January 2020. DN-to-middle cerebellar peduncle (MCP) SI ratios on T1WI were determined. A repeated-measures ANOVA was performed to compare the T1WI SI ratio between children exposed to GBCA in each of the two periods and controls. Pearson correlation analysis was conducted to determine any correlation between SI ratios and confounding parameters. Results T1WI SI ratio was significantly higher in those who had only L-GBCA (1.005±0.087) or subsequent mcGBCA gadobutrol (1.002±0.104) than in control groups 1 (0.927±0.041; P<0.001) and 2 (0.930±0.041; P=0.002), respectively, but no significant difference of the T1WI SI ratio was noted between L-GBCA period and subsequent mcGBCA gadobutrol period ( P=0.917). T1WI SI ratios and the L-GBCA administration number revealed a modest but significant correlation (correlation coefficient=0.034; P=0.016). Conclusion Previous administration of gadopentetate dimeglumine is associated with increased T1WI SI in the DN, while subsequent administration of gadobutrol does not demonstrate any additional SI increase in the pediatric brain.

scholarly journals Malondialdehyde levels can be measured in serum and saliva by using a fast HPLC method with visible detection / Determinarea printr-o metodă HPLC-VIS rapidă a concentraţiilor serice şi salivare ale malondialdehidei

2016 ◽  
Vol 24 (3) ◽  
pp. 319-326 ◽  
Author(s):  
Erzsébet Fogarasi ◽  
Mircea Dumitru Croitoru ◽  
Ibolya Fülöp ◽  
Enikő Nemes-Nagy ◽  
Robert Gabriel Tripon ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
Free Radicals ◽  
Unsaturated Fatty Acids ◽  
Pearson Correlation ◽  
Living Organism ◽  
Hplc Method ◽  
Limit Of Quantification ◽  
Pearson Correlation Test ◽  
Repeated Sample

Abstract Oxidative stress appears when the amount of free radicals that are formed in a living organism exceed its spin-trapping ability. One of the most dangerous free radicals that are formed in the human body is the hydroxyl radical. It can alter several biomolecules, including the unsaturated fatty acids; this process is known as lipid peroxidation and can lead to cell necrosis and generation of several harmful byproducts including malondialdehyde, which serves also as a biomarker of oxidative stress. A new HPLC method with visible detection was developed for the detection of malondialdehyde in human serum and saliva samples. The method was verified in terms of specificity, linearity, limits of detection (0.35 ng/ml), limit of quantification (1.19 ng/ml), recovery (90.13±10.25 – 107.29±14.33) and precision (3.84±1.49% – 6.66±1.76%). An analysis time of only 1 minute was obtained and no interferences from the matrices were observed. Statistical analysis (Pearson correlation test) showed a moderate correlation (R = 0.5061, p = 0.0099) between serum and saliva concentrations (N = 25). The possibility of measuring salivary concentrations of malondialdehyde extents the applications of oxidative stress/lipid peroxidation estimations to categories of population unreachable before (pregnant women, small children, etc); repeated sample studies are also easier to make.

scholarly journals Are metric parameters sufficient alone in evaluation of the patellar instability? New angular measuring parameters

2017 ◽  
Vol 25 (1) ◽  
pp. 230949901668449 ◽  
Author(s):  
Alper Deveci ◽  
Deniz Cankaya ◽  
Serdar Yilmaz ◽  
Ersin Celen ◽  
Bulent Sakman ◽  
...  
Keyword(s):  
Statistical Analysis ◽  
Strong Correlation ◽  
Patellar Instability ◽  
Pearson Correlation ◽  
Trochlear Groove ◽  
Rotational Movement ◽  
Pearson Correlation Test ◽  
Angular Measuring ◽  
Metric Measurement ◽  
Tibia Shaft

Purposes: When the evaluation of patellar instability is examined from the aspect of the conical-cylindrical anatomy of the tibia, metric measurement parameters such as the tuberositas tibia (TT)–trochlear groove (TG) and patellar tendon (PT) insertion–trochlear groove (TG) distances are not sufficient. We asked whether defined angular parameters reveal the rotational movement of the tuberositas tibia on the tibia shaft, additional to the metric parameters and there is a correlation between the metric and angular parameters. Methods: 19 patients with patellar instability and 22 patients without patellar instability were evaluated. For all patients, two angle and three length parameters were evaluated on the slices taken. Evaluations were made of the TT-TG, the midpoint of the PT insertion-TG distances, the anatomic midpoint of the dome of the TT-TG, the TG-PT angle, and the TG-dome angle (DA). The Pearson correlation test was used for the statistical analysis of correlations between groups. Results: A statistically significant increase was determined in the patellar instability group in the TG-DA and TG-PT angle values compared to the group without patellar instability ( p < 0.05). In both groups, a positive and strong correlation was determined between the TT-TG and the TG-PT and dome of the TT-TG distances, but no statistically significant correlation was determined between the tuberositas TT-TG and TG-PT angle and TG-DA. Conclusion: Metric parameters may not be sufficient alone in the evaluation of patellar instability. Metric parameters should be supported by additional angular parameters which reveal the rotational movement of the TT on the tibia shaft.

scholarly journals Randomized Exercise Trial of Aromatase Inhibitor–Induced Arthralgia in Breast Cancer Survivors

2015 ◽  
Vol 33 (10) ◽  
pp. 1104-1111 ◽  
Author(s):  
Melinda L. Irwin ◽  
Brenda Cartmel ◽  
Cary P. Gross ◽  
Elizabeth Ercolano ◽  
Fangyong Li ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Survivors ◽  
Strength Training ◽  
Aerobic Exercise ◽  
Usual Care ◽  
Repeated Measures ◽  
Joint Pain ◽  
Breast Cancer Survivors ◽  
Pain Scores ◽  
The Impact

Purpose Arthralgia occurs in up to 50% of breast cancer survivors treated with aromatase inhibitors (AIs) and is the most common reason for poor AI adherence. We conducted, in 121 breast cancer survivors receiving an AI and reporting arthralgia, a yearlong randomized trial of the impact of exercise versus usual care on arthralgia severity. Patients and Methods Eligibility criteria included receiving an AI for at least 6 months, reporting ≥ 3 of 10 for worst joint pain on the Brief Pain Inventory (BPI), and reporting < 90 minutes per week of aerobic exercise and no strength training. Participants were randomly assigned to exercise (150 minutes per week of aerobic exercise and supervised strength training twice per week) or usual care. The BPI, Western Ontario and McMaster Universities Osteoarthritis (WOMAC) index, and Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire were completed at baseline and at 3, 6, 9, and 12 months. Intervention effects were evaluated using mixed-model repeated measures analysis, with change at 12 months as the primary end point. Results Over 12 months, women randomly assigned to exercise (n = 61) attended 70% (± standard deviation [SD], 28%) of resistance training sessions and increased their exercise by 159 (± SD, 136) minutes per week. Worst joint pain scores decreased by 1.6 points (29%) at 12 months among women randomly assigned to exercise versus a 0.2-point increase (3%) among those receiving usual care (n = 60; P < .001). Pain severity and interference, as well as DASH and WOMAC pain scores, also decreased significantly at 12 months in women randomly assigned to exercise, compared with increases for those receiving usual care (all P < .001). Conclusion Exercise led to improvement in AI-induced arthralgia in previously inactive breast cancer survivors.

scholarly journals Construction Sector Contribution to Economic Stability: Malaysian GDP Distribution

2021 ◽  
Vol 13 (9) ◽  
pp. 5012
Author(s):  
Wesam Salah Alaloul ◽  
Muhammad Ali Musarat ◽  
Muhammad Babar Ali Rabbani ◽  
Qaiser Iqbal ◽  
Ahsen Maqsoom ◽  
...  
Keyword(s):  
Sustainable Development ◽  
Construction Industry ◽  
Pearson Correlation ◽  
Impulse Response Function ◽  
Equilibrium Analysis ◽  
Construction Sector ◽  
Causality Test ◽  
Vector Error Correction ◽  
The World ◽  
Pearson Correlation Test

The construction sector exerts an exceptional impact on economic development all over the world. Adequate buildings and infrastructures made by the construction sector ensure that a country reaches certain targets like social development, industrialization, freight transportation, sustainable development, and urbanization. This study aims to determine the construction sector’s connectivity with other sectors through complex linkages that contribute immensely to the economy and gross domestic product (GDP). The data were collected from the Department of Statistics Malaysia and the World Bank from the year 1970 to 2019, and the Pearson correlation test, the cointegration test, and the Granger causality test were conducted. The vector error correction model (VECM) was created for short-term and long-term equilibrium analysis and impulse response function (IRF) was performed to study construction industry behavior. Afterwards, the forecasting was done for the year 2020 to 2050 of the Malaysian economy and GDP for the required sectors. It was revealed that some sectors, such as agriculture and services, have forward linkages while other sectors, such as manufacturing and mining, are independent of construction sector causality, which signifies the behavior of the contributing sectors when a recession occurs, hence generating significant revenue. The Malaysian economy is moving towards sustainable production with more emphasis on the construction sector. The outcome can be used as a benchmark by other countries to achieve sustainable development. The significance of this study is its usefulness for experts all over the world in terms of allocating resources to make the construction sector a sustainable sector after receiving a shock. A sustainable conceptual framework has been suggested for global application that shows the factors involved in the growth of the construction industry to ensure its sustainable development with time.

PSXIII-26 Supplementation with a polyphenolic pine bark extract reduces ammonia nitrogen production in a RUSITEC system as determined by principal component analysis

2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 435-436
Author(s):  
Nelson Vera ◽  
Constanza Gutierrez ◽  
Pamela Williams ◽  
Cecilia Fuentealba ◽  
Rodrigo Allende ◽  
...  
Keyword(s):  
Principal Component Analysis ◽  
Repeated Measures ◽  
Pearson Correlation ◽  
Principal Component ◽  
Component Analysis ◽  
Ammonia Nitrogen ◽  
Pine Bark ◽  
Bark Extract ◽  
Ruminal Fermentation ◽  
Fermentation Parameters

Abstract The aim of the study was to correlate the effects of supplementation with a polyphenolic pine bark extract (PBE) in diets with different forage to concentrate (F:C) ratio on methane (CH4), ammonia nitrogen (NH3–N) production and ruminal fermentation parameters using the Rumen Simulation Technique (RUSITEC). The experimental diets were F:C 70:30 (HF) or F:C 30:70 (HC) with or without 2% PBE on a DM basis. The four diets were isoproteic (15% CP), with similar OM (HF 94% and HC 96%), but different NDF (HF 40% and HC 25%). The treatments, in duplicate, were assigned in an 8 fermenter RUSITEC apparatus. Incubations were run twice, with 5 days of sampling after 10 days adaptation. The experimental design was a 2x2 factorial arrangement in a randomized complete block with repeated measures. Pearson correlation and principal component analysis (PCA) were conducted to elucidate relationships among PBE total polyphenols (TP) and the variables evaluated. The TP was highly correlated with NH3–N (r = –0.98; P &lt; 0.001) and butyrate (r = –0.85; P &lt; 0.001), and had a high correlation with propionate (r = 0.75; P &lt; 0.001) and acetate (r = 0.68; P = 0.001). Correlation with total VFA was moderate (r = –0.59; P = 0.006), and CH4 yield and IVDMD there were not correlated (r ≤ –0.07; P ≥ 0.188). The PCA (KMO = 0.655; BTS &lt; 0.001) shows that 75.2% of the total variation is explained by the first two principal components (PC1 = 46.5% and PC2 = 28.7%). In the score plot, PC1 discriminated between diets with and without PBE, while the PC2 separated based on NDF. The loading plot showed that TP and propionate were clustered, and had inverse directions to NH3–N. In conclusion, the PBE supplementation reduces NH3–N production in a RUSITEC system without decreasing CH4 yield or negatively affecting ruminal fermentation parameters.

Evaluating Employees' Commitment in Islamic Work Ethics Perspective

2014 ◽  
Vol 2 (4) ◽  
pp. 87-94
Author(s):  
Nur`Ain Achim ◽  
Hairunnisa Ma’amor ◽  
Norhidayah Mohd Rashid
Keyword(s):  
Affective Commitment ◽  
Pearson Correlation ◽  
Future Research ◽  
Kuala Lumpur ◽  
Continuance Commitment ◽  
Work Ethics ◽  
Financial Firms ◽  
Pearson Correlation Test ◽  
The Relationship ◽  
Structured Questionnaire

Objective - The study purposes three objectives, which is to recognize the level of employees' commitment (EC) among employees, to identify the level of IWE application among employees, and to investigate the relationship between EC and IWE. Methodology/Technique - The data was collected through a structured questionnaire from employees working at selected financial firms in Kuala Lumpur and has been statistically analysed using SPSS. Findings - The results showed that the levels of employees' commitment and IWE among employees are high, however the Pearson correlation test shows there is no significant relationship between EC and IWE. Hence, it is recommended for future research to explore a different angle of the management dimension to be tested with IWE and expand the context into a multidisciplinary field. Novelty - This research helps to broaden the employees' knowledge about the work ethics in Islamic perspectives and apply it in their organization. Type of Paper - Empirical Keywords : Organizational commitment; employees commitment; affective commitment; normative commitment; continuance commitment; Islamic; work ethics.

THE INFLUENCE OF STUDENTS LEARNING STYLE AND LEARNING INTEREST ON THE LEARNING OUTCOMES OF PHYSICS CLASS X IPA DURING THE COVID-19 PANDEMIC

2021 ◽  
Vol 9 (3) ◽  
pp. 132-143
Author(s):  
Albert Lumbu ◽  
Bonefasius Y Boy ◽  
Muhamad Akbar
Keyword(s):  
Learning Styles ◽  
Learning Outcomes ◽  
Learning Style ◽  
Significant Influence ◽  
Pearson Correlation ◽  
Physics Learning ◽  
Significance Level ◽  
Pearson Correlation Test ◽  
Learning Interest ◽  
Learning Together

This study aims to determine whether there are: 1) the influence of learning styles on physics learning outcomes, 2) the influence of interest in learning on physics learning outcomes, 3) the influence of learning styles and interest in learning together on physics learning outcomes in class X SMA Negeri 1 Nimboran . This research was conducted at SMA Negeri 1 Nimboran in April - May 2021. The subjects in this study were all 52 students of class X majoring in science and the objects of research were learning styles, interest in learning and physics learning outcomes. The instruments used are questionnaires and documentation. Data analysis was carried out using the Pearson correlation test with a significance level of 0.05 and a regression test which resulted in conclusions as a result of the study. The results showed that, 1) there was a significant influence of learning style on physics learning outcomes with a contribution of 50.8%, 2) there was a significant influence of interest in learning on physics learning outcomes with a contribution of 60.9%, 3) there were significant influence of learning style and interest in learning, together on the learning outcomes of physics with a contribution of 64.3% influence

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