scholarly journals ABDOMINAL AORTIC ANEURYSM COMPLICATED BY DISSEMINATED INTRAVASCULAR COAGULATION (DIC)

1987 ◽  
Vol 48 (6) ◽  
pp. 829-832 ◽  
Author(s):  
Koichi TANAKA ◽  
Katsuaki ITO ◽  
Shigetsugu OHGI ◽  
Minoru TSUJIMOTO ◽  
Minoru OKADA ◽  
...  
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Disseminated Intravascular Coagulation ◽  
Intravascular Coagulation ◽  
Abdominal Aortic

scholarly journals Disseminated intravascular coagulation caused by abdominal aortic aneurysm

1986 ◽  
Vol 4 (2) ◽  
pp. 184-186 ◽  
Author(s):  
Robert W. Thompson ◽  
David H. Adams ◽  
Jon R. Cohen ◽  
John A. Mannick ◽  
Anthony D. Whittemore
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Disseminated Intravascular Coagulation ◽  
Intravascular Coagulation ◽  
Abdominal Aortic

Heparin-induced Thrombocytopenia in Two Patients Undergoing Abdominal Aortic Aneurysm Surgery

2009 ◽  
Vol 16 (1) ◽  
pp. 110-114 ◽  
Author(s):  
Takaki Sugimoto ◽  
Takefumi Matsuo ◽  
Keiko Wanaka
Keyword(s):  
Platelet Count ◽  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Unfractionated Heparin ◽  
Disseminated Intravascular Coagulation ◽  
Platelet Factor 4 ◽  
Platelet Factor ◽  
Heparin Induced Thrombocytopenia ◽  
Intravascular Coagulation ◽  
Abdominal Aortic

We have experienced 2 cases of heparin-induced thrombocytopenia during unfractionated heparin treatment for disseminated intravascular coagulation after surgery for an abdominal aortic aneurysm. In the first case, as a symptom of disseminated intravascular coagulation gradually improved with antithrombin concentrates and heparin treatment, mesenteric artery thrombosis suddenly occurred, associated with a >50% decrease in platelet count on the 11th day. Although the platelet counts were increasing due to heparin cessation, clinical symptom and coagulation abnormalities worsened to multiple organ failure. In the second case, the platelet count decreased to <10 × 104/µL on the 13th day after the start of unfractionated heparin anticoagulation along with continuous hemodiafiltration, which was indicated for postoperative renal failure. The extracorporeal circuit clotted frequently under an adequate dose of unfractionated heparin. Serologically, heparin—platelet factor 4 complex antibodies were repeatedly detected by enzyme-linked immunosorbent assay. Argatroban, a direct thrombin inhibitor, was introduced as an alternative to unfractionated heparin, and the platelet count improved with a decrease in titers of the antibodies. Disseminated intravascular coagulation is a common complication in cases of abdominal aortic aneurysm and is usually treated in association with unfractionated heparin. It is important to recognize the onset of heparin-induced thrombocytopenia that acute declines in the platelet count and appearance of thrombosis with positive for heparin—platelet factor 4 complex antibodies would suddenly occur in clinical course of disseminated intravascular coagulation.

Disseminated intravascular coagulation caused by abdominal aortic aneurysm

1986 ◽  
Vol 4 (2) ◽  
pp. 184-186 ◽  
Author(s):  
Robert W. Thompson ◽  
David H. Adams ◽  
Jon R. Cohen ◽  
John A. Mannick ◽  
Anthony D. Whittemore
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Disseminated Intravascular Coagulation ◽  
Intravascular Coagulation ◽  
Abdominal Aortic
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