scholarly journals Laparoscopic Emergency Appendectomy in a Severely Obese Patient with a Body Mass Index of 56.7 kg/m2

Author(s):  
Mizuki MORIYAMA ◽  
Hironori FUJIEDA ◽  
Miho FURUTA ◽  
Shinya WATANABE ◽  
Keiji AIZU ◽  
...  
2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Ana Paula dos Santos Rodrigues ◽  
Lorena Pereira Souza Rosa ◽  
Hugo Delleon da Silva ◽  
Elisângela de Paula Silveira-Lacerda ◽  
Erika Aparecida Silveira

Background. ThePPARG2Pro12Ala (rs1801282) andIL6-174G >C (rs1800795) have important function in body weight regulation and a potential role in obesity risk. We aimed to investigate the association betweenPPARG2Pro12Ala andIL6-174G >C variants and the genotypes interaction with body composition, metabolic markers, food consumption, and physical activity in severely obese patients.Methods. 150 severely obese patients (body mass index (BMI) ≥ 35 kg/m2) from Central Brazil were recruited. Body composition, metabolic parameters, physical activity, and dietary intake were measured. The genotype was determined by the qPCR TaqMan Assays System. Multiple linear regression and multiple logistic regression models were fitted adjusting for confounders.Results. Ala carriers of the Pro12Ala polymorphism had higher adiposity measures (BMI:p=0.031, and fat mass:p=0.049) and systolic blood pressure (p=0.026) compared to Pro homozygotes. We found no important associations between the -174G >C polymorphism and obesity phenotypes. When genotypes were combined, individuals with genotypes ProAla + AlaAla and GC + CC presented higher BMI (p=0.029) and higher polyunsaturated fatty acids (PUFAs) consumption (p=0.045) compared to the ones with genotypes ProPro and GG, and individuals carriers of thePPARG2Ala allele only (genotype ProAla + AlaAla and GG) had higher fat mass and systolic and diastolic blood pressure compared to the ones with genotypes ProPro and GG.Conclusions. Severely obese individuals carrying the Ala allele of thePPARG2Pro12Ala polymorphism had higher measures of adiposity and blood pressure, while no important associations were found for theIL6-174G >C polymorphism.


1994 ◽  
Vol 15 (1) ◽  
pp. 29-34 ◽  
Author(s):  
Stephen P. Messier ◽  
Angela B. Davies ◽  
Dominic T. Moore ◽  
Shala E. Davis ◽  
Robert J. Pack ◽  
...  

The purpose of our study was to determine the effects of severe obesity on the foot mechanics of adult females. Twenty-nine adult females between the ages of 20 and 48 years volunteered as subjects for this investigation. The subjects were separated into a severely obese (O) group (body mass index = 41.14 ± 2.61; N = 16) and a normal weight control group (body mass index = 20.84 ± 0.47; N = 13). A Locam camera (100 Hz) positioned perpendicular to the subjects’ posterior aspect was used to film the rearfoot movement of the subjects during the final 15 sec of a 10 min treadmill walk. The O group had a significantly greater touchdown angle ( P = .05), more total eversion range of motion ( P = .001), and a faster maximum eversion velocity ( P < .001). Moreover, analysis of dynamic foot angles indicated that the O group had significantly ( P = .003) more forefoot abduction. Finally, anthropometric data revealed statistically different ( P < .001) Q angle measurements between the O and control groups. The results of this study suggest that severely obese females have significantly greater rearfoot motion, foot angle, and Q angle values than normal weight females.


Circulation ◽  
2015 ◽  
Vol 131 (suppl_1) ◽  
Author(s):  
Abhishek Sharma ◽  
Carl J Lavie ◽  
Jeffrey S Borer ◽  
Ajay Vallakati ◽  
Francisco Lopez-Jimenez ◽  
...  

Objective: To investigate the relationship of body mass index (BMI) with total mortality, cardiac mortality and risk of hospitalization in patients with chronic heart failure (HF). Methods: A systematic search of studies published between 1966 to January 31, 2014 was conducted using Pub Med, CINAHL, Cochrane CENTRAL and the Web of Science databases. Studies reporting rate of total mortality, cardiac mortality and risk of hospitalization in patients with HF in various BMI categories [<20 kg/m2 (low); 20-24.9 kg/m2 (normal reference); 25-29.9 kg/m2 (overweight); 30-34.9 kg/m2 (obese); >=35 kg/m2 (severely obese)] were identified. Event rates were compared using a forest plot of relative risk using a random effects model assuming inter-study heterogeneity. Results: Two study authors independently reviewed the 124 articles and identified 6 for final analyses (N=22807). After mean follow up of 2.85 years, the risk of total mortality, cardiovascular (CV) mortality and of hospitalization was highest among patients with low BMI (RR 1.27 [95% CI 1.17 - 1.37]; 1.20 [95% CI 1.01 -1.43]; 1.19 [95% CI 1.09 - 1.30] respectively). Risk of cardiac mortality and hospitalization was lowest in overweight patients (RR0.79 [95% CI 0.70-0.90] and 0.92 [95% CI 0.86-0.97] respectively). Increasing degree of obesity failed to achieve a statistically significant effect on CV mortality (0.82 [0.64-1.05] and 0.71 [0.50-1.01] for obese and severely obese, respectively) and on hospitalization (0.99 [0.92-1.07] and 1.28 [0.88-1.87] for obese and severely obese, respectively) Conclusion: Risk of total mortality, cardiac mortality and hospitalization was highest among chronic HF patients who were underweight as defined by low BMI, whereas risk of cardiac mortality and hospitalization was lowest in the overweight. Further prospective studies are needed to investigate this association and apparent “overweight paradox” and explore potential underlying mechanisms for this association.


2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Randi Jepsen ◽  
Eivind Aadland ◽  
Lesley Robertson ◽  
Ronette L. Kolotkin ◽  
John Roger Andersen ◽  
...  

It is unknown how changes in physical activity may affect changes in quality of life (QoL) outcomes during lifestyle interventions for severely obese adults. The purpose of this study was to examine associations in the patterns of change between objectively assessed physical activity as the independent variable and physical, mental, and obesity-specific QoL and life satisfaction as the dependent variables during a two-year lifestyle intervention. Forty-nine severely obese adults (37 women;43.6±9.4years; body mass index42.1±6.0 kg/m2) participated in the study. Assessments were conducted four times using Medical Outcomes Study Short-Form 36 Health Survey (SF-36), Obesity-Related Problems (OP) scale, a single item on life satisfaction, and accelerometers. The physical component summary (PCS) score and the mental component summary (MCS) score were used as SF-36 outcomes. Associations were determined using linear regression analyses and reported as standardized coefficients (stand. coeff.). Change in physical activity was independently associated with change in PCS (stand. coeff. = 0.35,P=.033), MCS (stand. coeff. = 0.51,P=.001), OP (stand. coeff. = −0.31,  P=.018), and life satisfaction (stand. coeff. = 0.39,P=.004) after adjustment for gender, age, and change in body mass index.


2007 ◽  
Vol 9 (4) ◽  
pp. 498-505 ◽  
Author(s):  
T. D Adams ◽  
E. M Heath ◽  
M. J LaMonte ◽  
R. E Gress ◽  
R Pendleton ◽  
...  

2006 ◽  
Vol 20 (4) ◽  
Author(s):  
Jack Wang ◽  
Dympna Gallagher ◽  
John Thornton ◽  
Wen YU ◽  
Rich Weil ◽  
...  

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