scholarly journals A Case of a Pancreatic Neuroendocrine Tumor with Intraductal Growth and Fat Replacement in the Distal Pancreas

2017 ◽  
Vol 78 (11) ◽  
pp. 2525-2533
Author(s):  
Hiroaki TAKAHASHI ◽  
Yoshihiko OSAKA ◽  
Kazuhito UEMURA ◽  
Naotake HOMMA ◽  
Kazuaki SHIBUYA ◽  
...  
Keyword(s):  
Neuroendocrine Tumor ◽  
Pancreatic Neuroendocrine Tumor ◽  
Intraductal Growth ◽  
Fat Replacement ◽  
Distal Pancreas

scholarly journals Pancreatic Neuroendocrine Tumor with Benign Serous Cystadenoma: A Rare Entity

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Randhir Sagar Yadav ◽  
Ashik Pokharel ◽  
Shumneva Shrestha ◽  
Ashbita Pokharel ◽  
Deepshikha Gaire ◽  
...  
Keyword(s):  
Neuroendocrine Tumor ◽  
Histopathological Examination ◽  
Epigastric Pain ◽  
Pancreatic Neuroendocrine Tumor ◽  
Serous Cystadenoma ◽  
Neuroendocrine Neoplasm ◽  
Management Approach ◽  
Cystic Neoplasms ◽  
Distal Pancreas

Mixed serous-neuroendocrine neoplasm constitutes pancreatic serous cystic neoplasms and pancreatic neuroendocrine tumor, two tumor components with different underlying pathologies. The differentiation of these tumors is important as the management and prognosis depend on the pancreatic neuroendocrine tumor component. We report a case of mixed serous-neuroendocrine neoplasm in a 47-year-old female who presented with epigastric pain abdomen for two years. Imaging studies, tumor markers, thorough systemic evaluation, surgical resection, histopathological examination, and timely follow-up constituted our management approach. A 4 cm × 4 cm mass in the distal pancreas with multiple cysts in the pancreatic parenchyma containing serous fluid on distal pancreatectomy and splenectomy was found. The histopathological examination revealed combined benign serous cystadenoma and neuroendocrine tumor. She did not have any recurrence or metastasis by four years of follow-up.

scholarly journals Simultaneous laparoscopic resection of distal pancreas and liver nodule for pancreatic neuroendocrine tumor

2016 ◽  
Vol 2 ◽  
pp. 176-176
Author(s):  
Nicola Passuello ◽  
Michele Valmasoni ◽  
Gioia Pozza ◽  
Elisa Sefora Pierobon ◽  
Alberto Ponzoni ◽  
...  
Keyword(s):  
Neuroendocrine Tumor ◽  
Laparoscopic Resection ◽  
Pancreatic Neuroendocrine Tumor ◽  
Distal Pancreas

Simultaneous laparoscopic resection of distal pancreas and liver nodule for pancreatic neuroendocrine tumor

ASVIDE ◽  
2016 ◽  
Vol 3 ◽  
pp. 487-487
Author(s):  
Nicola Passuello ◽  
Michele Valmasoni ◽  
Gioia Pozza ◽  
Elisa Sefora Pierobon ◽  
Alberto Ponzoni ◽  
...  
Keyword(s):  
Neuroendocrine Tumor ◽  
Laparoscopic Resection ◽  
Pancreatic Neuroendocrine Tumor ◽  
Distal Pancreas

scholarly journals Pancreatic Neuroendocrine Tumor in the Setting of Dorsal Agenesis of the Pancreas

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Samih Nassif ◽  
Cecilia Ponchiardi ◽  
Teviah Sachs
Keyword(s):  
Diabetes Mellitus ◽  
Neuroendocrine Tumor ◽  
Gold Standard ◽  
Imaging Techniques ◽  
Pancreatic Head ◽  
Pancreatic Neuroendocrine Tumor ◽  
Related Literature ◽  
Presenting Symptoms ◽  
Distal Pancreas ◽  
Pancreatic Neoplasia

Dorsal agenesis of the pancreas (DAP) is an uncommon embryological abnormality where there is absence of the distal pancreas. DAP is mostly asymptomatic, but common presenting symptoms include diabetes mellitus, abdominal pain, pancreatitis, enlarged pancreatic head, and, in a few cases, polysplenia. MRCP and ERCP are the gold standard imaging techniques to demonstrate the absence of the dorsal pancreatic duct. The literature on the association of pancreatic neoplasia and DAP is limited. We present the case of a pancreatic neuroendocrine tumor in a patient with dorsal agenesis of the pancreas, with a review of the related literature.

Case report: Refractory hypercalcemia due to a pancreatic neuroendocrine tumor misdiagnosed as adenocarcinoma

2020 ◽  
Author(s):  
Mirella Hage ◽  
Ségolène Hescot ◽  
Amani Asnacios ◽  
Sophia Bakopoulou ◽  
Laure Cazabat ◽  
...  
Keyword(s):  
Case Report ◽  
Neuroendocrine Tumor ◽  
Pancreatic Neuroendocrine Tumor

scholarly journals Heterogeneity of the Clinical Presentation of the MEN1 LRG_509 c.781C>T (p.Leu261Phe) Variant Within a Three-Generation Family

Genes ◽  
2021 ◽  
Vol 12 (4) ◽  
pp. 512
Author(s):  
Aleksandra Gilis-Januszewska ◽  
Anna Bogusławska ◽  
Kornelia Hasse-Lazar ◽  
Beata Jurecka-Lubieniecka ◽  
Barbara Jarząb ◽  
...  
Keyword(s):  
Neuroendocrine Tumor ◽  
Clinical Presentation ◽  
Age Of Onset ◽  
Malignant Tumors ◽  
Genetic Disorder ◽  
Family Members ◽  
Pancreatic Neuroendocrine Tumor ◽  
Index Patient ◽  
Generation Family

Multiple neuroendocrine neoplasia type 1 (MEN1) is a rare genetic disorder with an autosomal dominant inheritance, predisposing carriers to benign and malignant tumors. The phenotype of MEN1 syndrome varies between patients in terms of tumor localization, age of onset, and clinical aggressiveness, even between affected members within the same family. We describe a heterogenic phenotype of the MEN1 variant c.781C>T (LRG_509t1), which was previously reported only once in a family with isolated hyperparathyroidism. A heterozygous missense variant in exon 4 of the gene was identified in the sequence of the MEN1 gene, i.e., c.781C>T, leading to the amino acid change p.Leu261Phe in a three-generation family. In the screened family, 5/6 affected members had already developed hyperparathyroidism. In the index patient and two other family members, an aggressive course of pancreatic neuroendocrine tumor (insulinoma and non-functioning neuroendocrine tumors) with dissemination was diagnosed. In the index patient, late diagnosis and slow progression of the disseminated neuroendocrine tumor have been observed (24 years of follow-up). The very rare variant of MEN1, LRG_509t1 c.781C>T /p.Leu261Phe (LRG_509p1), diagnosed within a three-generation family has a heterogenic clinical presentation. Further follow-up of the family members should be carried out to confirm the spectrum and exact time of clinical presentation.

Management of the primary tumor in patients with metastatic pancreatic neuroendocrine tumor: a contemporary single-institution review

2009 ◽  
Vol 197 (3) ◽  
pp. 376-381 ◽  
Author(s):  
Matias Bruzoni ◽  
Purvi Parikh ◽  
Rolando Celis ◽  
Chandrakanth Are ◽  
Quan P. Ly ◽  
...  
Keyword(s):  
Neuroendocrine Tumor ◽  
Primary Tumor ◽  
Pancreatic Neuroendocrine Tumor ◽  
Single Institution
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