scholarly journals Multiple Venous Thromboses Complicated by Congenital Antithrombin III Deficiency, after Surgery for Small Intestinal Necrosis—A Case Report—

2016 ◽  
Vol 77 (12) ◽  
pp. 2915-2919
Author(s):  
Goichi ENDO ◽  
Takashi GUNJI ◽  
Osamu KONNO
Keyword(s):  
Case Report ◽  
Antithrombin Iii ◽  
Intestinal Necrosis ◽  
Antithrombin Iii Deficiency ◽  
Small Intestinal ◽  
Venous Thromboses

scholarly journals Antithrombin III deficiency, hypertriglyceridaemia, and venous thromboses.

BMJ ◽  
1978 ◽  
Vol 1 (6113) ◽  
pp. 621-622 ◽  
Author(s):  
O H Gyde ◽  
M D Middleton ◽  
G R Vaughan ◽  
D J Fletcher
Keyword(s):  
Antithrombin Iii ◽  
Antithrombin Iii Deficiency ◽  
Venous Thromboses

scholarly journals Antithrombin III deficiency: decreased synthesis of a biochemically normal molecule

Blood ◽  
1982 ◽  
Vol 60 (1) ◽  
pp. 78-83
Author(s):  
DR Ambruso ◽  
BD Leonard ◽  
RD Bies ◽  
L Jacobson ◽  
WE Hathaway ◽  
...  
Keyword(s):  
Normal Control ◽  
Antithrombin Iii ◽  
Polyacrylamide Gel Electrophoresis ◽  
White Female ◽  
Breakdown Rate ◽  
Chromogenic Assay ◽  
Normal Behavior ◽  
At Iii ◽  
Antithrombin Iii Deficiency ◽  
Venous Thromboses

A 29-yr-old white female has suffered from recurrent venous thromboses over the last 12 yr. Plasma antithrombin III (AT-III) levels were 48% of normal by immunoelectrophoresis and 56% by chromogenic assay. Three of four siblings and the father had similar AT-III levels without associated venous thromboses. Heparin-Sepharose chromatography demonstrated normal behavior of the patient's AT-III. Her purified AT- III could not be distinguished from AT-III purified from a normal control either by SDS polyacrylamide gel electrophoresis or by crossed immunoelectrophoresis, and the heparin cofactor activity and the progressive antithrombin activity of both AT-III samples were identical. Turnover studies were made in the patient using her own purified AT-III labeled with 131I, (*I). The results did not differ significantly from studies made with autologous *I-AT-III in two normal control women. Her fractional breakdown rate of 0.54 total plasma AT- III per day compared with 0.45 and 0.52 in the controls. These studies indicate that the patient synthesizes a normal AT-III molecule at half normal rates.

Hereditary antithrombin III deficiency: Case report and review of recent therapeutic advances

1986 ◽  
Vol 21 (2) ◽  
pp. 215-221 ◽  
Author(s):  
Nancy Miller ◽  
Mae B. Hultin ◽  
Mohanambal Gounder ◽  
M. Hosein Zarrabi
Keyword(s):  
Case Report ◽  
Antithrombin Iii ◽  
Antithrombin Iii Deficiency
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