scholarly journals A CASE OF RADIATION ENTERITIS WITH PERFORATED PERITONITIS CAUSED BY A PIECE OF EGGSHELL

2011 ◽  
Vol 72 (2) ◽  
pp. 375-378
Author(s):  
Hirotaka KITAMURA ◽  
Kazuya MAEDA ◽  
Tamonn MIYANAGA ◽  
Kenji DODEN ◽  
Masakazu HATTORI ◽  
...  
Keyword(s):  
Radiation Enteritis ◽  
Perforated Peritonitis

scholarly journals Publisher Correction: Effects of Thymoquinone on radiation enteritis in mice

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Qinlian Hou ◽  
Linlin Liu ◽  
Yinping Dong ◽  
Jing Wu ◽  
Liqing Du ◽  
...  
Keyword(s):  
Radiation Enteritis

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Effect of electrolyzed strong acid water on peritoneal irrigation of experimental perforated peritonitis

Surgery Today ◽  
2009 ◽  
Vol 39 (6) ◽  
pp. 514-517 ◽  
Author(s):  
Akio Kubota ◽  
Keisuke Nose ◽  
Takeo Yonekura ◽  
Takuya Kosumi ◽  
Katsuji Yamauchi ◽  
...  
Keyword(s):  
Strong Acid ◽  
Acid Water ◽  
Perforated Peritonitis

Radiation Enteritis

2014 ◽  
Vol 16 (5) ◽  
Author(s):  
Ali H. Harb ◽  
Carla Abou Fadel ◽  
Ala I. Sharara
Keyword(s):  
Radiation Enteritis

Global gene expression profiles reveal an increase in mRNA levels of collagens, MMPs, and TIMPs in late radiation enteritis

2004 ◽  
Vol 287 (4) ◽  
pp. G875-G885 ◽  
Author(s):  
Carine Strup-Perrot ◽  
Denis Mathé ◽  
Christine Linard ◽  
Dominique Violot ◽  
Fabien Milliat ◽  
...  
Keyword(s):  
Gene Expression ◽  
Extracellular Matrix ◽  
Expression Profiles ◽  
Cdna Array ◽  
Muscularis Propria ◽  
Gelatin Zymography ◽  
Tissue Inhibitors Of Metalloproteinases ◽  
Radiation Enteritis ◽  
Mrna Levels ◽  
Fixed Tissue

Radiation enteritis, a common complication of radiation therapy for abdominal and pelvic cancers, is characterized by severe transmural fibrosis associated with mesenchymal cell activation, tissue disorganization, and deposition of fibrillar collagen. To investigate the mechanisms involved in this pathological accumulation of extracellular matrix, we studied gene expression of matrix components along with that of genes involved in matrix remodeling, matrix metalloproteinases (MMPs), and tissue inhibitors of metalloproteinases (TIMPs). Hybrid selection on high-density cDNA array, real-time RT-PCR, gelatin zymography and imunohistochemistry were used to characterize the mRNA expression profile, activity, and tissue location of extracellular matrix-related genes in radiation enteritis compared with healthy ileum. cDNA array analysis revealed a strong induction of genes coding for collagens I, III, IV, VI, and VIII, SPARC, and tenascin-C, extracellular-matrix degrading enzymes (MMP-1, -2, -3, -14, -18+19), and metalloproteinase inhibitors (TIMP-1, -2, plasminogen activator inhibitor-1) in radiation enteritis. This increase was correlated with the degree of infiltration of the mucosa by inflammatory cells, and the presence of differentiated mesenchymal cells in the submucosa and muscularis propria. Despite the fact that expression of collagens, MMPs, and TIMPs simultaneously increase, quantification of net collagen deposition shows an overall accumulation of collagen. Our results indicate that late radiation enteritis tissues are subjected to active process of fibrogenesis as well as fibrolysis, with a balance toward fibrogenesis. This demonstrates that established fibrotic tissue is not scarred fixed tissue but is subjected to a dynamic remodeling process.

Late morbidity and mortality in 109 patients operated on for radiation enteritis

1998 ◽  
Vol 114 ◽  
pp. A12-A13
Author(s):  
A. Fingerhut ◽  
JL Gouzi ◽  
JM Hay ◽  
B Millat
Keyword(s):  
Morbidity And Mortality ◽  
Radiation Enteritis ◽  
Late Morbidity

scholarly journals HDR brachytherapy and supervoltage external beam therapy of cervical cancer: Protection of the intestinal tract during the treatment

2002 ◽  
Vol 10 (1) ◽  
pp. 13-17 ◽  
Author(s):  
Sasa Ljubenkovic
Keyword(s):  
Small Bowel ◽  
Standard Technique ◽  
Acute Radiation ◽  
Watery Diarrhoea ◽  
Radiation Enteritis ◽  
High Dose ◽  
Non Invasive ◽  
Dose Volume ◽  
Patient Table ◽  
One Year

BACKGROUND: During radiotherapy in most of the irradiated patients occur the symptoms of acute radiation enteritis, less frequently cystitis or proctitis. The aim of this work was to apply non invasive exclusion methods to reduce the small bowel volume within the pelvic high dose volume and indirectly to reduce the number and severity of acute radiation enteritis METHODS: A total number of 183 patients were enrolled in our prospective randomised investigation we performed at the Clinic of Oncology in Knez Selo during one year. Ninety patients from E-group were irradiated with the standard technique two opposite parallel fields on the Mevatron-7445 linear accelerator (SIEMENS) patient-table, while 93 from C-group were irradiated under special conditions on our unique patient-table (PT) manufactured at our special demands by the Jugorendgen Ei-Ni? factory Brachytherapy was administered with RALT technique in both groups with isotope machine BUCHLER. RESULTS: Individual application of exclusion techniques led to protection of over 50% of the small bowel (118-1065 cm3) in 30/43 (70%) patients, and even in 10/43 (23%) more than 90% of the small bowel was protected (118-835 cm3), which would otherwise be irradiated with conventional techniques. None of the patients from E-group (out of 90) had more than 8 stools a day (G3), while in C-group there were 20 such cases Seventy-seven percent of the patients from E-group had formed stool, while the percent in C-group was 29. In C-group 40% of the patients had so called "watery stools"; in E-group the percent was 4. Out of 53 patients from K-group with mobile small bowel, 21 (40%) had "watery diarrhoea". CONCLUSION: Measures to prevent radiation enteritis should be taken before (surgical) or during (non invasive) radiotherapy. At the Clinic of Oncology in Knez Selo, individual application of small bowel exclusion techniques using the unique patient-table (JUGORENDGEN Ei-Ni?) led to protection of the small bowel during radiotherapy of uterine malignancies, which was reflected in a significantly reduced number and severity of acute enteritis symptoms.

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