scholarly journals SOLITARY DUODENAL METASTASIS FROM RENAL CELL CARCINOMA TWELVE YEARS AFTER NEPHRECTOMY PRESENTING AS GASTROINTESTINAL BLEEDING

2009 ◽  
Vol 70 (3) ◽  
pp. 735-739
Author(s):  
Yusuke AKAMARU ◽  
Takeyoshi YUMIBA ◽  
Yoshio YAMASAKI ◽  
Yoshikazu MORIMOTO ◽  
Hiroko OKUDA
Keyword(s):  
Renal Cell Carcinoma ◽  
Gastrointestinal Bleeding ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Duodenal Metastasis

scholarly journals Duodenal Metastasis from Renal Cell Carcinoma presenting as Gastrointestinal Bleed

JMS SKIMS ◽  
2012 ◽  
Vol 15 (1) ◽  
pp. 65-68
Author(s):  
Mohammad Ashraf Teli ◽  
Omar J Shah ◽  
Aleem M Jan ◽  
Nazir Ahmad Khan
Keyword(s):  
Renal Cell Carcinoma ◽  
Gastrointestinal Bleeding ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Late Recurrence ◽  
Endoscopic Biopsy ◽  
First Case ◽  
Duodenal Metastasis ◽  
Immuno Histochemistry ◽  
Gi Bleed

Malignant causes account for 1–4% of upper gastrointestinal bleeding (GI-bleed). In absence of widespread nodal and visceral metastatic disease, isolated duodenal metastasis from renal cell carcinoma (RCC) is very rare. Consequently, gastrointestinal bleeding from renal cell carcinoma metastases is an infrequent and often un-recognized manifestation of this disease. Here, we describe case of a 52 year-old man in whom metastasis arising from renal cell carcinoma developed in the duodenum 8 years after nephrectomy as the first relapse. The patient presented with severe anemia due to occult GI bleed. The diagnosis was confirmed by endoscopic biopsy and immuno-histochemistry (IHC).Palliative local resection of the tumor was attempted, however, patient had progression of the disease and developed liver metastasis with pleural effusion and succumbed to his disease. Since, late recurrence/metastasis is characteristic of renal cell carcinoma, careful long-term follow-up is needed to pick up an early relapse. To our knowledge, this is the 20th case of duodenal metastasis from RCC and the first case from Kashmir valley of Indian sub-continent reported in literature. JMS 2012;15(1):65-68.

scholarly journals Emergency Pancreatoduodenectomy with Preservation of Gastroduodenal Artery for Massive Gastrointestinal Bleeding due to Duodenal Metastasis by Clear Cell Renal Cell Carcinoma in a Patient with Celiac Artery Stenosis

2014 ◽  
Vol 2014 ◽  
pp. 1-5
Author(s):  
Kyriakos Neofytou ◽  
Alexandros Giakoustidis ◽  
Martin Gore ◽  
Satvinder Mudan
Keyword(s):  
Renal Cell Carcinoma ◽  
Gastrointestinal Bleeding ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Clear Cell ◽  
Gastroduodenal Artery ◽  
Uneventful Recovery ◽  
Cell Renal Cell Carcinoma ◽  
Massive Gastrointestinal Bleeding ◽  
Duodenal Metastasis

Duodenal metastasis from renal cell carcinoma is rare, and even rarer is a massive gastrointestinal bleeding from such tumours. Coeliac occlusive disease, although rarely symptomatic, can lead to ischaemic changes with anastomotic dehiscence and leaks when a patient undergoes pancreatoduodenectomy. A 41-year-old man with known metastasis to the adrenal glands and the second part of the duodenum close to the ampulla of Vater from clear cell renal cell carcinoma was admitted to our department due to massive gastrointestinal bleeding from the duodenal metastasis. Endoscopic control of the bleed was not possible, while the bleeding vessel embolization was able to control the haemorrhage only temporarily. An angiography during the embolization demonstrated the presence of stenosis of the coeliac artery and also hypertrophic inferior pancreaticoduodenal arteries supplying the proper hepatic artery via the gastroduodenal artery (GDA). The patient underwent emergency pancreatoduodenectomy with preservation of the gastroduodenal artery. The patient had an uneventful recovery and did not experience further bleeding. Also the blood flow to the liver was compromised as shown by the normal liver function tests (LFTs) postoperatively. To the best of our knowledge, this is the first report of a preservation of the GDA during an emergency pancreatoduodenectomy.

scholarly journals A Rare Cause of Upper Gastrointestinal System Bleeding: Duodenal Metastasis of Renal Cell Carcinoma

2020 ◽  
Author(s):  
Muhammet Yener AKPINAR ◽  
Metin UZMAN ◽  
Gülçin GÜLER ŞIMŞEK ◽  
Evrim KAHRAMANOĞLU AKSOY ◽  
Ferdane PIRINÇÇI SAPMAZ ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Gastrointestinal System ◽  
Duodenal Metastasis ◽  
Upper Gastrointestinal

scholarly journals An Unusual Case of Gastrointestinal Bleeding in Metastatic Renal Cell Carcinoma

2020 ◽  
Vol 13 (2) ◽  
pp. 738-741
Author(s):  
Niamh Peters ◽  
Clara Lightner ◽  
John McCaffrey
Keyword(s):  
Renal Cell Carcinoma ◽  
Gastrointestinal Bleeding ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Unusual Case ◽  
Upper Gastrointestinal Bleeding ◽  
Cell Cancer ◽  
Metastatic Spread ◽  
Lung Lymph ◽  
Upper Gastrointestinal

Approximately 340 patients are diagnosed with renal cell cancer (RCC) in Ireland each year. Metastatic spread to the lung, lymph nodes and bones is common. Metastatic spread to the gastrointestinal tract, including the small bowel, is a rare phenomenon. Therapeutic advances have led to an improved overall survival in RCC and, as a result, unusual sites of metastatic spread are becoming more common. We present the case of a 68-year-old gentleman presenting with upper gastrointestinal bleeding as a result of metastases to the duodenum from renal cell carcinoma.

scholarly journals Recurrent Renal Cell Carcinoma with Synchronous Tumor Growth in Azygoesophageal Recess and Duodenum: A Rare Cause of Anemia and Upper Gastrointestinal Bleeding

2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
Vamshidhar R. Vootla ◽  
Muhammad Kashif ◽  
Masooma Niazi ◽  
Suresh K. Nayudu
Keyword(s):  
Renal Cell Carcinoma ◽  
Gastrointestinal Bleeding ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Upper Gastrointestinal Bleeding ◽  
Synchronous Tumor ◽  
Acute Upper Gastrointestinal Bleeding ◽  
Recurrent Renal Cell Carcinoma ◽  
Sites Of Metastases ◽  
Upper Gastrointestinal

Renal cell carcinoma (RCC) has potential to present with distant metastasis several years after complete resection. The common sites of metastases include the lungs, bones, liver, renal fossa, and brain. RCCs metastasize rarely to the duodenum, and duodenal metastasis presenting with acute gastrointestinal bleed is infrequently reported in literature. We present a case of synchronous presentation of duodenal and azygoesophageal metastasis manifesting as acute upper gastrointestinal bleeding, four years after undergoing nephrectomy for RCC. The patient underwent further workup and was treated with radiation. The synchronous presentation is rare and stresses the importance of searching for recurrence of RCC in patients presenting with acute gastrointestinal bleeding.

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