scholarly journals A CASE OF ADVANCED GASTRIC CANCER WITH PARA-AORTIC LYMPH NODE METASTASIS RESPONDING TO NEOADJUVANT CHEMOTHERAPY WHICH LEADS TO A PATHOLOGICAL COMPLETE RESPONSE

2008 ◽  
Vol 69 (4) ◽  
pp. 815-819 ◽  
Author(s):  
Satoru MATONO ◽  
Hiroyuki HORIUCHI ◽  
Yukiya KISHIMOTO ◽  
Takamasa FUKUMITU ◽  
Fumihiro YOSHIMURA ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Neoadjuvant Chemotherapy ◽  
Advanced Gastric Cancer ◽  
Pathological Complete Response ◽  
Complete Response ◽  
Node Metastasis ◽  
Aortic Lymph Node

scholarly journals A case of stage IV gastric cancer with para-aortic lymph node metastasis showing pathological complete response after neoadjuvant chemotherapy

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Yuki Katsura ◽  
Takehiro Okabayashi ◽  
Manabu Matsumoto ◽  
Kazuhide Ozaki ◽  
Yuichi Shibuya
Keyword(s):  
Gastric Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Pathological Complete Response ◽  
Stage Iv ◽  
Complete Response ◽  
Conversion Surgery ◽  
Stage Iv Gastric Cancer ◽  
Node Metastasis ◽  
Aortic Lymph Node

Abstract Background Stage IV advanced gastric cancer with para-aortic lymph node metastasis (PALM) is considered unresectable. Systemic chemotherapy is the treatment of choice for such tumors, while conversion surgery may be a treatment option in the case chemotherapy is effective but R0 resection is possible. We report a case of stage IV gastric cancer with PALM that showed pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) using S-1, oxaliplatin, and trastuzumab (SOX+HER). Case presentation A 69-year-old woman who was diagnosed with type 4 stage IV gastric cancer with PALM underwent five courses of NAC with the SOX+HER regimen. The primary tumor and the PALM shrank after treatment, suggesting that the NAC induced a partial response. We performed a total gastrectomy plus distal pancreaticosplenectomy with para-aortic lymph node dissection. Histological analysis revealed no remnant cancer cells in the primary tumor or the lymph nodes, confirming a pCR. The postoperative course was uneventful, and the patient was discharged on day 14 after the operation. S-1 was started as adjuvant chemotherapy, and the patient remains alive without recurrence 2 months after surgery. Conclusion This case shows the possibility of conversion surgery after SOX+HER therapy for stage IV advanced gastric cancer with PALM.

scholarly journals A case of pathological complete response after chemotherapy by S-1 and gemcitabine for a pancreatic cancer with para-aortic lymph node metastasis

Suizo ◽  
2014 ◽  
Vol 29 (6) ◽  
pp. 898-904 ◽  
Author(s):  
Hiroshi KURAHARA ◽  
Kosei MAEMURA ◽  
Yuko MATAKI ◽  
Masahiko SAKODA ◽  
Satoshi IINO ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Pathological Complete Response ◽  
Complete Response ◽  
Node Metastasis ◽  
Aortic Lymph Node

scholarly journals A Case of Advanced Gastric Cancer with Para-Aortic Lymph Node Metastasis from Co-Occurring Prostate Cancer

2017 ◽  
Vol 17 (1) ◽  
pp. 93
Author(s):  
Miyeong Park ◽  
Sang-Ho Jeong ◽  
Young-Joon Lee ◽  
Ji-Ho Park ◽  
Sang-Kyung Choi ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Gastric Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Advanced Gastric Cancer ◽  
Node Metastasis ◽  
Aortic Lymph Node
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