scholarly journals Primary Hyperparathyroidism Caused by Ectopic Parathyroid Tumor.

2002 ◽  
Vol 63 (10) ◽  
pp. 2353-2357 ◽  
Author(s):  
Toshihiro MASATSUGU ◽  
Hiroyuki YAMASHITA ◽  
Tsukasa MURAKAMI ◽  
Shin WATANABE ◽  
Shinya UCHINO ◽  
...  
Author(s):  
Saul Suster ◽  
Cesar A. Moran

2017 ◽  
Vol 10 (3) ◽  
pp. 1105-1111
Author(s):  
Andre Navarro ◽  
Josanne Vassallo ◽  
Joseph Galea

An elderly lady was diagnosed with primary hyperparathyroidism after being admitted to hospital with pyelonephritis and constipation. A sestamibi parathyroid scan demonstrated increased uptake in the upper mediastinum, suggesting an ectopic mediastinal parathyroid adenoma. The 4-mm adenoma was successfully removed through a mini-sternotomy incision using a gamma probe to identify the gland from the surrounding tissue. The patient made an uneventful recovery.


1984 ◽  
Vol 105 (3) ◽  
pp. 350-353 ◽  
Author(s):  
J. L. C. Ch'ng ◽  
A. Kaiser ◽  
J. Lynn ◽  
G. F. Joplin

Abstract. Total parathyroidectomy is required to cure neonatal primary hyperparathyroidism (NPH) as any parathyroid remnant quickly becomes hyperplastic, causing recurrent hypercalcaemia. We present a patient with NPH who had total removal of his eutopic parathyroid glands but continued to have parathyroid hormone secretion from presumed ectopic parathyroid tissue. Hypercalcaemia initially recurred but normal calcium homeostasis was established as the child grew older. We postulate that the underlying defect in NPH is decreased sensitivity to the serum ionic calcium feedback inhibition at the parathyroid receptor level and that this sensitivity can improve with age.


1996 ◽  
Vol 37 (3P2) ◽  
pp. 720-726 ◽  
Author(s):  
C. Tziakouri ◽  
E. Eracleous ◽  
S. Skannavis ◽  
A. Pierides ◽  
P. Symeonides ◽  
...  

Purpose: To evaluate the significance of preoperative localization of abnormal parathyroid glands to the surgical outcome in patients with primary hyperparathyroidism. Material and Methods: Thirty-nine patients with primary hyperparathyroidism were studied preoperatively with US (39 patients), CT (30 patients) and MR imaging (18 patients). The overall diagnostic accuracy for US was 87%, CT 66% and MR 94%. In patients with a single parathyroid adenoma US was the most cost-effective localization technique with a detection rate of 96%. CT had a lower detection rate (78%) but was of particular value for fairly large ectopic adenomas in the root of the neck. MR imaging was a good confirmatory test (93%). In patients with multiple gland disease (primary hyperplasia and multiple adenomas), no single localization study alone was sufficient. Combination of all 3 studies, however, alerted the physician to the presence of disease in more than one gland in 87% of these patients. Conclusion: US, CT and MR imaging followed by surgery performed by an experienced surgeon provided good clinical results in 39 patients with primary hyperparathyroidism. Preoperative localization was especially useful in patients with primary parathyroid hyperplasia or multiple adenomas and in patients with ectopic parathyroid adenomas in the root of the neck. We recommend identification of all abnormal parathyroid glands prior to surgery.


2021 ◽  
Vol 25 (2) ◽  
pp. 133-137
Author(s):  
A. V. Karalkin ◽  
L. I. Ippolitov ◽  
S. P. Pasha

Case study: a parathyroid tumor ectopic to the mediastinum. The diagnostic capabilities and advantages of the 99mТс-sestamibi SPECT/CT hybrid method in the preoperative localization of abnormally located parathyroma are demonstrated.


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