scholarly journals Coexistence of Noninvasive Ductal Carcinoma with a Phyllodes Tumor. A Case Report.

2001 ◽  
Vol 62 (11) ◽  
pp. 2640-2643
Author(s):  
Koji MATSUO ◽  
Haruhiko CHIGIRA ◽  
Takehito KATO ◽  
Masaomi SUZUKI ◽  
Yoshihisa SHIBATA ◽  
...  
2014 ◽  
Vol 10 (4) ◽  
pp. 239-241 ◽  
Author(s):  
Muhammet Kadri Colakoglu ◽  
Erdinc Yenidogan ◽  
Gokhan Giray Akgul ◽  
Sultan Cigdem Irkkan ◽  
Yilmaz Ozdemir ◽  
...  

2010 ◽  
Vol 2 (2) ◽  
pp. 223-228 ◽  
Author(s):  
YOSHINORI NIO ◽  
CHIKAGE IGUCHI ◽  
KAZUHIKO TSUBOI ◽  
RIRUKE MARUYAMA

2006 ◽  
Vol 67 (10) ◽  
pp. 2319-2323
Author(s):  
Hiroki ODAWARA ◽  
Tsunehiro ISHIDA ◽  
Hiroshi NAGAOKA ◽  
Akira OGAWA ◽  
Jun HORIGUCHI ◽  
...  

2018 ◽  
Vol 2 (2) ◽  
pp. 72
Author(s):  
Mine ÖZŞEN ◽  
Şahsine TOLUNAY ◽  
Mustafa Şehsuvar GÖKGÖZ

2021 ◽  
Vol 100 (6) ◽  

Introduction: Phyllodes tumors of the breast are rare and very distinct types of mammary neoplasms. They are characterized by their biphasicity, i.e. the presence of stromal and epithelial components at the same time. Malignancy is determined by the degree of stromal differentiation. The coexistence of the malignant epithelial component is a very rare phenomenon. Dozens of cases of simultaneous phyllodes tumor and epithelial malignancy have been reported so far. Nevertheless, the biological nature of this process is still an unexplained and a controversial topic. Case report: In this paper, we present a case of a patient with a suddenly enlarging lesion in the breast. According to the first surgical resection, a diagnosis of high-grade malignant phyllodes tumor was made with fibrosarcoma differentiation, stromal overgrowth and suppression of the epithelial component. Examination of scar resistence in early postoperative period revealed a triple-negative invasive low-differentiated breast carcinoma with very high proliferative activity, thus malignization of the epithelial component of the tumor occurred. Shortly, a diagnosis of second recurrence was made, treatment included axillary lymph node dissection (ALND) with a negative histological findings. The patient underwent complex adjuvant chemotherapy and radiotherapy and remained disease free 3 years after the surgery. Conclusion: Coexistence of phyllodes tumor and the breast carcinoma is very rare. The article describes the first published case, which documents the subsequent development of invasive low-differentiated ductal carcinoma immediately after resection of high-grade phyllodes tumor. Treatment and prognosis are generally determined by the characteristics of the carcinomatous component.


1986 ◽  
Vol 72 (2) ◽  
pp. 187-190 ◽  
Author(s):  
Anni Grove ◽  
Lone Deibjerg Kristensen

The first reported case in the world literature of a ductal carcinoma in situ located within a phyllodes tumor of the breast is presented. Previously reported cases of carcinoma in phyllodes tumors are reviewed, and the relationship between carcinoma arising in fibroadenomas and phyllodes tumors is discussed.


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