scholarly journals THE SIGNIFICANCE OF HISTOPATHOLOGIC FINDINGS IN THE SUBMUCOSAL INVASIVE FRONT OF EARLY COLORECTAL CARCINOMA IN TERMS OF REGIONAL LYMPH NODE METASTASIS

1998 ◽  
Vol 59 (3) ◽  
pp. 629-635
Author(s):  
Yoshinari MOCHIZUKI ◽  
Takashi HIRAI ◽  
Tomoyuki KATO ◽  
Yasuhiro SHIMIZU ◽  
Yasuhiro KODERA ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Colorectal Carcinoma ◽  
Regional Lymph Node ◽  
Regional Lymph Node Metastasis ◽  
Invasive Front ◽  
Node Metastasis ◽  
Early Colorectal Carcinoma ◽  
Histopathologic Findings

Histopathological predictors of regional lymph node metastasis at the invasive front in early colorectal cancer

2011 ◽  
Vol 59 (3) ◽  
pp. 470-481 ◽  
Author(s):  
Yuri Akishima-Fukasawa ◽  
Yukio Ishikawa ◽  
Yoshikiyo Akasaka ◽  
Miwa Uzuki ◽  
Naomi Inomata ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Regional Lymph Node ◽  
Regional Lymph Node Metastasis ◽  
Early Colorectal Cancer ◽  
Invasive Front ◽  
Node Metastasis

scholarly journals The Role of HIF-1alpha in Regional Lymph Nodes Metastasis in Colorectal Adenocarcinoma

2018 ◽  
Vol 54 (1) ◽  
pp. 1
Author(s):  
Ladyna Rumapar ◽  
Sjahjenny Mustokoweni ◽  
Alphania Rahniayu
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Colorectal Carcinoma ◽  
Colorectal Adenocarcinoma ◽  
Regional Lymph Node ◽  
Regional Lymph Node Metastasis ◽  
Trigger Factor ◽  
High Morbidity ◽  
Regional Lymph Nodes ◽  
Node Metastasis

Colorectal carcinoma has high morbidity and mortality rate worldwide, in which over 90% are adenocarcinoma. Colorectal carcinoma is one of the most cancer that metastasize to the lymph node. Angiogenesis have an important role in tumor growth and metastasis. Hypoxia is the trigger factor for angiogenesis. Hypoxia induced factor-1 (HIF-1) is one critical protein directly reacting to hypoxia. HIF-1alpha, a HIF-1 subunit, is an important regulator of angiogenesis. This study analyzed HIF-1a expression in colorectal adenocarcinoma with and without regional lymph node metastasis. This study was to prove that HIF-1a has a role in regional lymph node metastasis in colorectal adenocarcinoma. An analytical observational study was conducted on thirty formalin fixed paraffin-embedded colorectal adenocarcinoma tissues from Anatomic Pathology Laboratory of Dr. Soetomo Hospital. Detection of HIF-1alpha expressions were performed with immunohistochemistry method, using HIF-1alpha antibody. It were statistically analyzed using Mann-Whitney and Kruskal- Wallis methods. There were no significant differences in the expression of HIF-1alpha in colorectal adenocarcinoma with or without lymph node (LN) metastasis (p>0.05). As a conclusion, this study showed that HIF-1alpha has no role in LN metastasis in colorectal adenocarcinoma.

EVALUATION OF CLINICAL AND PARACLINICAL FEATURES IN PATIENTS WITH CARCINOMA OF ORAL CAVITY

2016 ◽  
pp. 56-60
Author(s):  
Van Minh Nguyen ◽  
Hong Loi Nguyen ◽  
Thi Kim Anh Dang
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Oral Cavity ◽  
Tumor Size ◽  
Regional Lymph Node ◽  
Regional Lymph Node Metastasis ◽  
Female Ratio ◽  
Histopathological Grade ◽  
Node Metastasis ◽  
Metastasis Rate

Background: To evaluate the clinical, hystopathologycal features and correlation between lymph node metastasis and hystopathologycal grade in patients with carcinoma of the oral cavity. Materials and Methods: From July 2015 to July 2016, 32 patients with carcinoma of the oral cavity at Hue Central Hospital Results: The most common age group from 51 to 60 years and the male/female ratio was 1.9/1. Tumor were usually observed around the the tongue (40.6%) and oral floor (34.4%). Most of the tumor size is larger than 2 cm diameters (> 80%). The regional lymph node metastasis rate was 43.8% and there was a positive correlation between lymph node metastasis and tumor size (p <0.05). Squamous-cell carcinoma was mainly type of histopathology. Difference between the rate of lymph node metastasis in patient groups with different histopathological grade show no statistical significance (p> 0.05). Conclusion: the greater tumor, the higher regional lymph node metastasis. There is no relationship between the lymph node metastasis rate and histopathological grade of oral carcinoma. Key words: : carcinoma of oral cavity, tumor size, lymph node metastasis, histopathology

Parosteal (Juxtacortical) Chondrosarcoma of the Humerus Associated With Regional Lymph Node Metastasis

1993 ◽  
Vol &NA; (290) ◽  
pp. 168???173 ◽  
Author(s):  
KEIJI MATSUMOTO ◽  
SINSUKE HUKUDA ◽  
MICHIHITO ISHIZAWA ◽  
YASUO SARUHASHI ◽  
HIDETOSHI OKABE ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Regional Lymph Node ◽  
Regional Lymph Node Metastasis ◽  
Node Metastasis
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