scholarly journals Adrenal insufficiency from bilateral adrenal hemorrhage during anticoagulation therapy: a case report

2021 ◽  
Vol 28 (6) ◽  
pp. 558-559
Author(s):  
Tadahiko Seki ◽  
Hideki Asai ◽  
Hidetada Fukushima
Keyword(s):  
Case Report ◽  
Adrenal Insufficiency ◽  
Anticoagulation Therapy ◽  
Adrenal Hemorrhage ◽  
Bilateral Adrenal Hemorrhage

scholarly journals Adrenal Insufficiency Secondary to Bilateral Adrenal Hemorrhage: A Case Report

Cureus ◽  
2020 ◽  
Author(s):  
Waiel A Bashari ◽  
Yadee M. M Myint ◽  
Mya L Win ◽  
Samson O Oyibo
Keyword(s):  
Case Report ◽  
Adrenal Insufficiency ◽  
Adrenal Hemorrhage ◽  
Bilateral Adrenal Hemorrhage

Catastrophic antiphospholipid syndrome with bilateral adrenal hemorrhage: a case report

2019 ◽  
Author(s):  
De Marchi Lucrezia ◽  
M K de Filette Jeroen ◽  
Sol Bastiaan ◽  
E Andreescu Corina ◽  
Kunda Rastislav ◽  
...  
Keyword(s):  
Case Report ◽  
Antiphospholipid Syndrome ◽  
Adrenal Hemorrhage ◽  
Catastrophic Antiphospholipid Syndrome ◽  
Bilateral Adrenal Hemorrhage

scholarly journals Bilateral Adrenal Hemorrhage in Coronavirus Disease 2019 Patient: A Case Report

2020 ◽  
Vol 105 (12) ◽  
pp. 3745-3749 ◽  
Author(s):  
Meir Frankel ◽  
Itamar Feldman ◽  
Michal Levine ◽  
Yigal Frank ◽  
Naama R Bogot ◽  
...  
Keyword(s):  
Adrenal Insufficiency ◽  
Rare Condition ◽  
Renal Vein Thrombosis ◽  
Adrenal Hemorrhage ◽  
Polymerase Chain Reaction Test ◽  
Primary Antiphospholipid Syndrome ◽  
Thromboembolic Events ◽  
Adrenal Axis ◽  
Bilateral Adrenal Hemorrhage ◽  
Life Threatening

Abstract Context Bilateral adrenal hemorrhage is a rare condition with potentially life-threatening consequences such as acute adrenal insufficiency. Early adrenal axis testing, as well as directed imaging, is crucial for immediate diagnosis and treatment. Coronavirus disease 2019 (COVID-19) has been associated with coagulopathy and thromboembolic events. Case description A 66-year-old woman presented with acute COVID-19 infection and primary adrenal insufficiency due to bilateral adrenal hemorrhage (BAH). She also had a renal vein thrombosis. Her past medical history revealed primary antiphospholipid syndrome (APLS). Four weeks after discharge she had no signs of COVID-19 infection and her polymerase chain reaction test for COVID-19 was negative, but she still needed glucocorticoid and mineralocorticoid replacement therapy. The combination of APLS and COVID-19 was probably responsible of the adrenal event as a “two-hit” mechanism. Conclusions COVID-19 infection is associated with coagulopathy and thromboembolic events, including BAH. Adrenal insufficiency is life threatening; therefore, we suggest that early adrenal axis testing for COVID-19 patients with clinical suspicion of adrenal insufficiency should be carried out.

Fatal Bilateral Adrenal Hemorrhage Following Acute Toluene Poisoning: A Case Report

1998 ◽  
Vol 36 (4) ◽  
pp. 365-368 ◽  
Author(s):  
Yoshito Kamijo ◽  
Kazui Soma ◽  
Ichiko Hasegawa ◽  
Takashi Ohwada
Keyword(s):  
Case Report ◽  
Adrenal Hemorrhage ◽  
Bilateral Adrenal Hemorrhage

scholarly journals Bilateral adrenal hemorrhage due to heparin-induced thrombocytopenia following partial nephrectomy – a case report

F1000Research ◽  
2014 ◽  
Vol 3 ◽  
pp. 24 ◽  
Author(s):  
Ashley G. Winter ◽  
Ranjith Ramasamy
Keyword(s):  
Case Report ◽  
Partial Nephrectomy ◽  
Pulmonary Embolus ◽  
Adrenal Hemorrhage ◽  
Renal Surgery ◽  
Heparin Induced Thrombocytopenia ◽  
Anticoagulation Treatment ◽  
Bilateral Adrenal Hemorrhage ◽  
Life Threatening

Heparin-induced thrombocytopenia (HIT) can cause severe life-threatening events such as bilateral adrenal hemorrhage (BAH). A 48-year-old female developed a pulmonary embolus (PE) following partial nephrectomy. The anticoagulation treatment for her PE was complicated by HIT and subsequent BAH. To the author’s knowledge, this is the first reported case of HIT-associated BAH following renal surgery.

scholarly journals BILATERAL ADRENAL HEMORRHAGE WITH ADRENAL INSUFFICIENCY AFTER DALTEPARIN USE POST HIP ATHROPLASTIES

2020 ◽  
Vol 6 (3) ◽  
pp. e141-e143 ◽  
Author(s):  
Robyn L. Houlden ◽  
Azraa Janmohamed
Keyword(s):  
Platelet Count ◽  
Adrenal Insufficiency ◽  
Epigastric Pain ◽  
Laboratory Data ◽  
Adrenal Hemorrhage ◽  
Nausea And Vomiting ◽  
Dvt Prophylaxis ◽  
Post Surgery ◽  
Bilateral Adrenal Hemorrhage ◽  
Hip Arthroplasties

Objective: Multiple case reports have implicated the use of heparin for deep vein thrombosis (DVT) prophylaxis with bilateral adrenal hemorrhage. Only 1 previous report has described this with the low molecular weight product, dalteparin. We report a case following bilateral hip arthroplasties. Methods: Clinical and laboratory data are presented. Results: A 69-year-old woman underwent bilateral total hip arthroplasties with dalteparin 5,000 international units subcutaneously daily for 30 days postoperatively. The patient's past medical history was unremarkable. She was discharged 5 days post-surgery and required readmission 1 day later for epigastric pain, nausea, and vomiting. Her platelet count was 91 × 109/L (normal, 150 to 400 × 109/L). She was discharged after 4 days with pain resolution. She presented 4 weeks later with nausea and vomiting for several days. Serum sodium was 123 mmol/L (normal, 133 to 145 mmol/L), potassium was 6.0 mmol/L (normal, 3.7 to 5.3 mmol/L), total calcium was 3.37 mmol/L (normal, 2.25 to 2.80 mmol/L), creatinine was 404 μmol/L (normal, 0 to 85 μmol/L), and her platelet count was normal. On short adrenocorticotropic hormone stimulation test, baseline plasma cortisol was 123 nmol/L and the peak was 129 nmol/L. She was treated with hydrocortisone, fludrocortisone, and 0.9% saline with resolution of symptoms and normalization of electrolytes, calcium, and renal function. Computed tomography showed bilateral adrenal masses. Core needle biopsy was consistent with necrosis. There were no bleeding disorders on hematologic work 3 months later. The most likely etiology of bilateral adrenal hemorrhage was heparin-induced thrombocytopenia from dalteparin. Conclusion: This case highlights the importance of vigilance for the complication of bilateral adrenal hemorrhage with adrenal insufficiency in patients receiving dalteparin for DVT prophylaxis.

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