scholarly journals A case of Kerstersia gyiorum detected in a chronic skin lesion on the lower extremity

2017 ◽  
Vol 24 (3) ◽  
pp. 337-340
Author(s):  
Jun Sugiura ◽  
Takashi Mato ◽  
Susumu Sekine ◽  
Fumihito Arima ◽  
Hidenori Oi ◽  
...  
Keyword(s):  
Skin Lesion ◽  
Lower Extremity ◽  
Chronic Skin ◽  
Kerstersia Gyiorum

scholarly journals Bacteremia Caused by Kerstersia gyiorum

2015 ◽  
Vol 53 (6) ◽  
pp. 1965-1967 ◽  
Author(s):  
A. Doran Bostwick ◽  
Cecelia Zhang ◽  
Katja Manninen ◽  
Joanne Touchberry ◽  
Shermalyn R. Greene ◽  
...  
Keyword(s):  
Lower Extremity ◽  
Content Type ◽  
Kerstersia Gyiorum ◽  
Human Infections

Kerstersiaspp. are an unusual cause of human infections. We report the first known case of bacteremia and sepsis due toKerstersia gyiorum, in a patient with chronic lower-extremity ulcers, and we review the literature on this uncommon pathogen.

scholarly journals Prurigo Nodularis after Radiotherapy: An Isoradiotopic Response?

2018 ◽  
Vol 2018 ◽  
pp. 1-3 ◽  
Author(s):  
Caspar Weel Krammer ◽  
Rami Mossad Ibrahim
Keyword(s):  
Lymph Node ◽  
Skin Lesion ◽  
Skin Disorder ◽  
Nasopharyngeal Cancer ◽  
Lymph Node Involvement ◽  
Prurigo Nodularis ◽  
Skin Malignancy ◽  
Node Involvement ◽  
History Of ◽  
Chronic Skin

Prurigo nodularis is a rare and chronic skin disorder with multiple, pruritic, and firm nodules. The exact pathophysiology is still unknown. Skin disorders appearing at sites of radiation can be defined as isoradiotopic. A 35-year-old male had developed a skin lesion in the left submandibular area on a base of irradiated skin which was initially suspected as a skin malignancy. The patient had a history of undifferentiated nasopharyngeal cancer with lymph node involvement which was treated by radiochemotherapy thirteen years previously. Histological examination confirmed that it was a case of prurigo nodularis which subsequently evolved at distant sites. This presentation may suggest a case of an isoradiotopic response.

scholarly journals PSENet: Psoriasis Severity Evaluation Network

2020 ◽  
Vol 34 (01) ◽  
pp. 800-807
Author(s):  
Yi Li ◽  
Zhe Wu ◽  
Shuang Zhao ◽  
Xian Wu ◽  
Yehong Kuang ◽  
...  
Keyword(s):  
Skin Lesion ◽  
Absolute Error ◽  
Severity Index ◽  
Input Image ◽  
Training Data ◽  
Clinical Practices ◽  
Fine Grained ◽  
Heavy Burden ◽  
Chronic Skin ◽  
Psoriasis Severity

Psoriasis is a chronic skin disease which affects hundreds of millions of people around the world. This disease cannot be fully cured and requires lifelong caring. If the deterioration of Psoriasis is not detected and properly treated in time, it could cause serious complications or even lead to a life threat. Therefore, a quantitative measurement that can track the Psoriasis severity is necessary. Currently, PASI (Psoriasis Area and Severity Index) is the most frequently used measurement in clinical practices. However, PASI has the following disadvantages: (1) Time consuming: calculating PASI usually takes more than 30 minutes which poses a heavy burden on dermatologists; and (2) Inconsistency: due to the complexity of PASI calculation, different or even the same dermatologist could give different scores for the same case. To overcome these drawbacks, we propose PSENet which applies deep neural networks to estimate Psoriasis severity based on skin lesion images. Different from typical deep learning frameworks for image processing, PSENet has the following characteristics: (1) PSENet introduces a score refine module which is able to capture the visual features of skin at both coarse and fine-grained granularities; (2) PSENet uses siamese structure in training and accepts pairwise inputs, which reduces the dependency on large amount of training data; and (3) PSENet can not only estimate the severity, but also locate the skin lesion regions from the input image. To train and evaluate PSENet, we work with professional dermatologists from a top hospital and spend years in building a golden dataset. The experimental results show that PSENet can achieve the mean absolute error of 2.21 and the accuracy of 77.87% in pair comparison, outperforming baseline methods. Overall, PSENet not only relieves dermatologists from the dull PASI calculation but also enables patients to track Psoriasis severity in a much more convenient manner.

Paracrystalline Aggregates of Psoriatic Keratin and Their Relation to Normal Keratin Structure

1985 ◽  
Vol 43 ◽  
pp. 680-681
Author(s):  
S. Trachtenberg ◽  
P.M. Steinert ◽  
B.L. Trus ◽  
A.C. Steven
Keyword(s):  
Cell Death ◽  
Stratum Corneum ◽  
Intermediate Filament ◽  
Skin Disease ◽  
Amorphous Matrix ◽  
Terminal Differentiation ◽  
Proteolytic Degradation ◽  
Horny Layer ◽  
Chronic Skin ◽  
Chronic Skin Disease

During terminal differentiation of vertebrate epidermis, certain specific keratin intermediate filament (KIF) proteins are produced. Keratinization of the epidermis involves cell death and disruption of the cytoplasm, leaving a network of KIF embedded in an amorphous matrix which forms the outer horny layer known as the stratum corneum. Eventually these cells are shed (desquamation). Normally, the processes of differentiation, keratinization, and desquamation are regulated in an orderly manner. In psoriasis, a chronic skin disease, a hyperkeratotic stratum corneum is produced, resulting in abnormal desquamation of unusually large scales. In this disease, the normal KIF proteins are diminished in amount or absent, and other proteins more typical of proliferative epidermal cells are present. There is also evidence of proteolytic degradation of the KIF.

Combining Values

2002 ◽  
Vol 7 (2) ◽  
pp. 1-4, 12 ◽  
Author(s):  
Christopher R. Brigham
Keyword(s):  
Lower Extremity ◽  
Upper Extremity ◽  
Evaluation Method ◽  
Proximal Phalanx ◽  
Common Error ◽  
The Third ◽  
Whole Person ◽  
Impairment Ratings ◽  
Upper Extremity Impairment ◽  
The Individual

Abstract To account for the effects of multiple impairments, evaluating physicians must provide a summary value that combines multiple impairments so the whole person impairment is equal to or less than the sum of all the individual impairment values. A common error is to add values that should be combined and typically results in an inflated rating. The Combined Values Chart in the AMA Guides to the Evaluation of Permanent Impairment, Fifth Edition, includes instructions that guide physicians about combining impairment ratings. For example, impairment values within a region generally are combined and converted to a whole person permanent impairment before combination with the results from other regions (exceptions include certain impairments of the spine and extremities). When they combine three or more values, physicians should select and combine the two lowest values; this value is combined with the third value to yield the total value. Upper extremity impairment ratings are combined based on the principle that a second and each succeeding impairment applies not to the whole unit (eg, whole finger) but only to the part that remains (eg, proximal phalanx). Physicians who combine lower extremity impairments usually use only one evaluation method, but, if more than one method is used, the physician should use the Combined Values Chart.

Quick Reference: Chapter 3: The Musculoskeletal System and Chapter 4: The Nervous System

2000 ◽  
Vol 5 (3) ◽  
pp. 4-4
Keyword(s):  
Nervous System ◽  
Lower Extremity ◽  
Musculoskeletal System ◽  
Multistep Method ◽  
Manual Muscle Testing ◽  
Motor Deficits ◽  
Lower Extremity Weakness ◽  
Residual Symptoms ◽  
Muscle Testing ◽  
Almost All

Abstract Lesions of the peripheral nervous system (PNS), whether due to injury or illness, commonly result in residual symptoms and signs and, hence, permanent impairment. The AMA Guides to the Evaluation of Permanent Impairment (AMA Guides), Fourth Edition, divides PNS deficits into sensory and motor and includes pain in the former. This article, which regards rating sensory and motor deficits of the lower extremities, is continued from the March/April 2000 issue of The Guides Newsletter. Procedures for rating extremity neural deficits are described in Chapter 3, The Musculoskeletal System, section 3.1k for the upper extremity and sections 3.2k and 3.2l for the lower limb. Sensory deficits and dysesthesia are both disorders of sensation, but the former can be interpreted to mean diminished or absent sensation (hypesthesia or anesthesia) Dysesthesia implies abnormal sensation in the absence of a stimulus or unpleasant sensation elicited by normal touch. Sections 3.2k and 3.2d indicate that almost all partial motor loss in the lower extremity can be rated using Table 39. In addition, Section 4.4b and Table 21 indicate the multistep method used for spinal and some additional nerves and be used alternatively to rate lower extremity weakness in general. Partial motor loss in the lower extremity is rated by manual muscle testing, which is described in the AMA Guides in Section 3.2d.

Q&A: Multiple Lower Extremity Impairments and AMA Guides, Third Edition, Revised

2017 ◽  
Vol 22 (2) ◽  
pp. 15-16
Author(s):  
Christopher R. Brigham ◽  
Kathryn Mueller ◽  
Steven Demeter ◽  
Randolph Soo Hoo
Keyword(s):  
Lower Extremity

Spinal Impairment Evaluation: Fifth Edition Changes

2001 ◽  
Vol 6 (1) ◽  
pp. 1-3
Author(s):  
Robert H. Haralson
Keyword(s):  
Spinal Cord ◽  
Lower Extremity ◽  
Range Of Motion ◽  
Upper Extremity ◽  
Spinal Cord Injuries ◽  
Clinical Findings ◽  
Fourth Edition ◽  
Treatment Results ◽  
Standard Terminology ◽  
Made In

Abstract The AMA Guides to the Evaluation of Permanent Impairment (AMA Guides), Fifth Edition, was published in November 2000 and contains major changes from its predecessor. In the Fourth Edition, all musculoskeletal evaluation and rating was described in a single chapter. In the Fifth Edition, this information has been divided into three separate chapters: Upper Extremity (13), Lower Extremity (14), and Spine (15). This article discusses changes in the spine chapter. The Models for rating spinal impairment now are called Methods. The AMA Guides, Fifth Edition, has reverted to standard terminology for spinal regions in the Diagnosis-related estimates (DRE) Method, and both it and the Range of Motion (ROM) Method now reference cervical, thoracic, and lumbar. Also, the language requiring the use of the DRE, rather than the ROM Method has been strengthened. The biggest change in the DRE Method is that evaluation should include the treatment results. Unfortunately, the Fourth Edition's philosophy regarding when and how to rate impairment using the DRE Model led to a number of problems, including the same rating of all patients with radiculopathy despite some true differences in outcomes. The term differentiator was abandoned and replaced with clinical findings. Significant changes were made in evaluation of patients with spinal cord injuries, and evaluators should become familiar with these and other changes in the Fifth Edition.

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