scholarly journals Sperm telomere length: Diagnostic and prognostic biomarker in male infertility (Review)

2020 ◽  
Author(s):  
Saira Amir ◽  
Elena Vakonaki ◽  
Konstantina Tsiminikaki ◽  
Manolis Tzatzarakis ◽  
Vasiliki Michopoulou ◽  
...  
Keyword(s):  
Male Infertility ◽  
Telomere Length ◽  
Prognostic Biomarker ◽  
Sperm Telomere Length

scholarly journals The association of male infertility with telomere length: A case control study

2021 ◽  
Vol 8 (4) ◽  
pp. 325-332
Author(s):  
Kate Deepali Rajesh ◽  
Puranam Vatsalaswamy ◽  
Manvikar Purshotam Rao
Keyword(s):  
Male Infertility ◽  
Telomere Length ◽  
Real Time ◽  
Real Time Pcr ◽  
Case Control Study ◽  
Case Control ◽  
Control Group ◽  
Significant Difference ◽  
Control Study ◽  
Sperm Telomere Length

To study the relevance of sperm telomere length and infertility in men. : Our case-control study included twenty-five males in couple with sub-fertility/infertility (test group) and twenty five healthy males (control group) with proven paternity in the age group 25 to 35 years. The Absolute Sperm Telomere length (aSTL) was measured by real-time PCR. We investigated whether any significant difference in the aSTL value existed between the groups and analysed the relationship between aSTL and other sperm parameters.The mean (SE) aSTL recorded in the infertile cases was significantly shorter than for the control group being 140.60 (6.66) Kb/genome and 239.63 (12.32) Kb/genome respectively (p <0.001) A weak correlation was eminent between aSTL kb/genome and the total sperm count mil/ml (rho= 0.04, p - 0.86), progressive sperm motility (rho= - 0.02, p=0.934) and sperm viability (rho= - 0.07 p=0.741) in the infertile group. The measurement of aSTL by real-time PCR is a simple and rapid method that offers further paramount information with respective to the quality of sperm. It is befitted for epidemiological studies, hence opening new perspectives in the evaluation of male infertility. Limitations - Our study was confined to men aged between 25 and 35 years. Further comparative studies are needed to explore the significance of STL and infertility in older males. Additional studies will help illumine the significance of aSTL as a prognostic biomarker in assisted reproduction.

scholarly journals Mild oxidative stress is beneficial for sperm telomere length maintenance

2016 ◽  
Vol 6 (2) ◽  
pp. 163 ◽  
Author(s):  
Swetasmita Mishra ◽  
Rajeev Kumar ◽  
Neena Malhotra ◽  
Neeta Singh ◽  
Rima Dada
Keyword(s):  
Oxidative Stress ◽  
Telomere Length ◽  
Sperm Telomere Length

scholarly journals Telomere length is a prognostic biomarker in elderly advanced ovarian cancer patients: a multicenter GINECO study

Aging ◽  
2015 ◽  
Vol 7 (12) ◽  
pp. 1066-1074 ◽  
Author(s):  
Claire Falandry ◽  
Béatrice Horard ◽  
Amandine Bruyas ◽  
Eric Legouffe ◽  
Jacques Cretin ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Telomere Length ◽  
Cancer Patients ◽  
Prognostic Biomarker ◽  
Advanced Ovarian Cancer

Sperm telomere length in motile sperm selection techniques: A qFISH approach

Andrologia ◽  
2017 ◽  
Vol 50 (2) ◽  
pp. e12840 ◽  
Author(s):  
R. Lafuente ◽  
E. Bosch-Rue ◽  
J. Ribas-Maynou ◽  
J. Alvarez ◽  
C. Brassesco ◽  
...  
Keyword(s):  
Telomere Length ◽  
Motile Sperm ◽  
Sperm Selection ◽  
Sperm Telomere Length

scholarly journals Associations of sperm telomere length with semen parameters, clinical outcomes and lifestyle factors in human normozoospermic samples

Andrology ◽  
2019 ◽  
Vol 8 (3) ◽  
pp. 583-593
Author(s):  
Stephane C. Berneau ◽  
Jennifer Shackleton ◽  
Clare Nevin ◽  
Basher Altakroni ◽  
George Papadopoulos ◽  
...  
Keyword(s):  
Telomere Length ◽  
Clinical Outcomes ◽  
Lifestyle Factors ◽  
Semen Parameters ◽  
Sperm Telomere Length

scholarly journals Sperm telomere length is positively associated with the quality of early embryonic development

2015 ◽  
Vol 30 (8) ◽  
pp. 1876-1881 ◽  
Author(s):  
Qingling Yang ◽  
Feifei Zhao ◽  
Shanjun Dai ◽  
Nan Zhang ◽  
Wanli Zhao ◽  
...  
Keyword(s):  
Embryonic Development ◽  
Telomere Length ◽  
Early Embryonic Development ◽  
Sperm Telomere Length
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