scholarly journals Histopathological evaluation including cytokeratin 13 and Ki-67 in the border between Lugol-stained and -unstained areas

2010 ◽  
Vol 24 (1) ◽  
Author(s):  
Ohta
Keyword(s):  
Ki 67 ◽  
Histopathological Evaluation ◽  
Cytokeratin 13

scholarly journals Histopathological specialized staining of oral lichen planus-induced fibrotic changes and surgical treatment of associated restricted mouth opening: a case report

2021 ◽  
Vol 45 (1) ◽  
Author(s):  
Atsushi Shudo
Keyword(s):  
Surgical Treatment ◽  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Histopathological Examination ◽  
Mouth Opening ◽  
Ki 67 ◽  
Collagen Formation ◽  
Immune Mediated ◽  
Cytokeratin 13 ◽  
Oral Lichen

Abstract Background Oral lichen planus is a chronic inflammatory and immune-mediated disease that affects the oral mucosa. Recent findings have suggested that oral lichen planus is often associated with submucosal fibrotic changes. Fibrotic changes in the buccal submucosa may cause restricted mouth opening. This report discusses the histopathological examination (including specialized staining) and surgical treatment for oral lichen planus-induced fibrotic changes. Case presentation Here, we describe a 63-year-old woman who had oral lichen planus with fibrotic changes. Her maximum mouth opening distance was approximately 30 mm due to submucosal fibrotic changes, and she exhibited gradual fibrosis progression. Histological examinations were performed to assess the oral lichen planus-induced fibrotic changes. Then, double Z-plasty were performed as treatment for restricted mouth opening. The immunohistochemical staining results were negative for cytokeratin 13 and positive in some layers for cytokeratin 17 and Ki-67/MIB-1. Masson's trichrome staining showed enhanced collagen formation. Postoperative mouth opening training enabled the patient to achieve a mouth opening distance of > 50 mm. Conclusion Our findings suggest that histopathological examination with specialized staining can aid in the evaluation of oral lichen planus-induced fibrotic changes, and that Z-plasty is effective for the treatment of restricted mouth opening due to oral lichen planus.

scholarly journals Cytokeratin 13, Cytokeratin 17, and Ki-67 Expression in Human Acquired Cholesteatoma and Their Correlation With Its Destructive Capacity

2017 ◽  
Vol 10 (3) ◽  
pp. 213-220 ◽  
Author(s):  
Mahmood A. Hamed ◽  
Seiichi Nakata ◽  
Kazuya Shiogama ◽  
Kenji Suzuki ◽  
Ramadan H. Sayed ◽  
...  
Keyword(s):  
Ki 67 ◽  
Cytokeratin 17 ◽  
Acquired Cholesteatoma ◽  
Cytokeratin 13

Diagnostic value of Ki-67 and cytokeratin 13 immunohistochemistry in oral precancerous lesions

2014 ◽  
Vol 72 (9) ◽  
pp. e157-e158
Author(s):  
T. Yagyuu ◽  
T. Kirita ◽  
Y. Ueyama ◽  
Y. Imai ◽  
K. Aoki ◽  
...  
Keyword(s):  
Precancerous Lesions ◽  
Diagnostic Value ◽  
Ki 67 ◽  
Cytokeratin 13 ◽  
Oral Precancerous Lesions

scholarly journals Lamellar keratoplasty in rabbits using an allogeneic free omental graft and omentum-derived mesenchymal cells associated with the canine amniotic membrane

2016 ◽  
Vol 46 (10) ◽  
pp. 1838-1845 ◽  
Author(s):  
Séfora Vieira da Silva Gouvêa de Barros ◽  
Marcela Aldrovani ◽  
Luciana Cenço Correa de Lacerda ◽  
Mônica Horr ◽  
Fábio Andrade Marinho ◽  
...  
Keyword(s):  
Amniotic Membrane ◽  
Clinical Signs ◽  
Corneal Opacity ◽  
Mesenchymal Cells ◽  
Lamellar Keratoplasty ◽  
Cell Group ◽  
Ki 67 ◽  
Clinical Assessments ◽  
Histopathological Evaluation ◽  
Omental Graft

ABSTRACT: The objective of this research was to evaluate the clinical and microscopic effects in rabbits of lamellar keratoplasty using allogeneic omentum associated with canine amniotic membrane (AM). Rabbits were divided into two groups: one received the allogeneic free omental graft covered with the AM (OM-graft group), while the other received the AM graft containing omental mesenchymal cells (OM-cell group). Clinical signs were evaluated on different postoperative days. After the clinical assessments, the rabbits were euthanized and their corneas were obtained for histopathology and immunohistochemistry (Ki-67, marker for proliferation). Both groups showed chemosis, blepharospasm, eye discharge, hyperemia, and corneal opacity/edema. Neovascularization was observed in the OM-cell group. Histopathological evaluation revealed epithelial islands within the stroma of OM-cell samples. Thirty days after surgery, complete corneal re-epithelialization had occurred in both groups. The OM-cell group showed more Ki-67 positive cells. The free omentum and its cells, combined with the AM, contributed to corneal repair, a process that was completed 30 days after lamellar keratoplasty.

scholarly journals Multivariate analyses of Ki‐67, cytokeratin 13 and cytokeratin 17 in diagnosis and prognosis of oral precancerous lesions

2014 ◽  
Vol 44 (7) ◽  
pp. 523-531 ◽  
Author(s):  
Takahiro Yagyuu ◽  
Chiho Obayashi ◽  
Yoshihiro Ueyama ◽  
Masato Takano ◽  
Yuu Tanaka ◽  
...  
Keyword(s):  
Multivariate Analyses ◽  
Precancerous Lesions ◽  
Ki 67 ◽  
Cytokeratin 17 ◽  
Diagnosis And Prognosis ◽  
Cytokeratin 13 ◽  
Oral Precancerous Lesions

1155: Histopathological Evaluation of the Uterosacral Ligament: Is this A Dependable Structure for Pelvic Reconstruction?

2004 ◽  
Vol 171 (4S) ◽  
pp. 304-305
Author(s):  
Emily E. Cole ◽  
Patrick B. Leu ◽  
Alex Gomelsky ◽  
Patricia Revelo ◽  
Heidi Shappell ◽  
...  
Keyword(s):  
Uterosacral Ligament ◽  
Pelvic Reconstruction ◽  
Histopathological Evaluation
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