scholarly journals Anticancer effects on TACC3 by treatment of paclitaxel in HPV-18 positive cervical carcinoma cells

2009 ◽  
Author(s):  
Park
Keyword(s):  
Cervical Carcinoma ◽  
Carcinoma Cells ◽  
Anticancer Effects ◽  
Hpv 18

scholarly journals Application of self-assembly peptides targeting the mitochondria as a novel treatment for sorafenib-resistant hepatocellular carcinoma cells

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Tae Ho Hong ◽  
M. T. Jeena ◽  
Ok-Hee Kim ◽  
Kee-Hwan Kim ◽  
Ho Joong Choi ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Antioxidant Enzymes ◽  
Self Assembly ◽  
Carcinoma Cells ◽  
Anticancer Activities ◽  
Anticancer Effects ◽  
Novel Treatment ◽  
Mitochondrial Ros ◽  
Appropriate Treatment ◽  
Apoptotic Effect

AbstractCurrently, there is no appropriate treatment option for patients with sorafenib-resistant hepatocellular carcinoma (HCC). Meanwhile, pronounced anticancer activities of newly-developed mitochondria-accumulating self-assembly peptides (Mito-FF) have been demonstrated. This study intended to determine the anticancer effects of Mito-FF against sorafenib-resistant Huh7 (Huh7-R) cells. Compared to sorafenib, Mito-FF led to the generation of relatively higher amounts of mitochondrial reactive oxygen species (ROS) as well as the greater reduction in the expression of antioxidant enzymes (P < 0.05). Mito-FF was found to significantly promote cell apoptosis while inhibiting cell proliferation of Huh7-R cells. Mito-FF also reduces the expression of antioxidant enzymes while significantly increasing mitochondrial ROS in Huh7-R cells. The pro-apoptotic effect of Mito-FFs for Huh7-R cells is possibly caused by their up-regulation of mitochondrial ROS, which is caused by the destruction of the mitochondria of HCC cells.

Nevirapine induces growth arrest and premature senescence in human cervical carcinoma cells

2008 ◽  
Vol 111 (2) ◽  
pp. 344-349 ◽  
Author(s):  
Konstantinos Stefanidis ◽  
Dimitris Loutradis ◽  
Leandros-Vassilios Vassiliou ◽  
Vasiliki Anastasiadou ◽  
Erasmia Kiapekou ◽  
...  
Keyword(s):  
Cervical Carcinoma ◽  
Growth Arrest ◽  
Carcinoma Cells ◽  
Premature Senescence ◽  
Human Cervical Carcinoma ◽  
Human Cervical Carcinoma Cells

EFFECTS OF PHOTODYNAMIC THERAPY MEDIATED BY EMODIN IN CERVICAL CARCINOMA CELLS

2021 ◽  
pp. 102394
Author(s):  
Ana Emília Brumatti Galiardi-Campoy ◽  
Francielly Cristina Machado ◽  
Tamara Carvalho ◽  
Antonio Claudio Tedesco ◽  
Paula Rahal ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cervical Carcinoma ◽  
Carcinoma Cells
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