Relation between CA125 levels and second-look operation for ovarian cancer

1997 ◽  
Author(s):  
H Nishimura ◽  
Y Kiyozuka ◽  
K Imamura ◽  
N Ohkura ◽  
F Murakami ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Second Look ◽  
Second Look Operation

scholarly journals Evaluation of staging, cytoreduction and second-look operation of 119 ovarian cancer patients

1997 ◽  
Vol 115 (5) ◽  
pp. 1542-1547
Author(s):  
Eddie Fernando Candido Murta ◽  
Jurandyr Moreira de Andrade ◽  
Maurício Mesquita Sabino de Freitas ◽  
Sérgio Bighetti
Keyword(s):  
Ovarian Cancer ◽  
Retrospective Study ◽  
Medical Records ◽  
Residual Disease ◽  
School Of Medicine ◽  
Second Look ◽  
Gynecology And Obstetrics ◽  
Data Source ◽  
Level Of Significance ◽  
Second Look Operation

OBJECTIVE:This study was conducted on patients with ovarian cancer in order to evaluate survival. DESIGN: A retrospective study of 119 cases of ovarian cancer from January 1977 to December 1992 with observation until 1993. LOCATION: Department of Gynecology and Obstetrics, Ribeirão Preto School of Medicine, São Paulo University. PARTICIPANTS: Of the 119 cases, 70 (58.8%) presented epithelial carcinomas and 21 (17.6%) tumors of the sexual girdle/stroma. DATA SOURCE: The data were obtained from the medical records of the patients. MEASUREMENT: Statistical analysis of survival time was based on the nonparametric Mann-Whitney test with the level of significance set at P < 0.05. RESULTS: The patients with a negative second look had a mean survival of 79.4 ± 48.5 months versus 24.2 ± 15.1 months for patients with a positive second look (P < 0.02). CONCLUSIONS: It is concluded that patients with a negative second look present a better prognosis compared to those with residual disease.

The second-look operation improves survival in suboptimally debulked stage III ovarian cancer patients

2005 ◽  
Vol 15 (1) ◽  
pp. 19-25 ◽  
Author(s):  
J. Rahaman ◽  
P. Dottino ◽  
T. S. Jennings ◽  
J. Holland ◽  
C. J. Cohen
Keyword(s):  
Ovarian Cancer ◽  
Residual Disease ◽  
Stage Iii ◽  
Single Institution ◽  
Primary Ovarian Cancer ◽  
Primary Surgery ◽  
Second Look ◽  
Survival Difference ◽  
Second Look Operation

In a single-institution retrospective cohort study, 230 patients were treated for stage III primary ovarian cancer and 175 became eligible for second-look operations by virtue of a complete clinical response after primary surgical cytoreduction and platinum-based combination chemotherapy. Of these, 109 underwent a second-look operation. Optimal primary cytoreduction was defined as residual disease ≤1 cm. Median follow-up was 68.3 months. Five-year survival for all the 230 stage III ovarian cancers was 43.4%. Among all eligible patients (n = 175), there was no survival difference (P = 0.67) in those having second look (57.3%, 5-year survival) versus no second look (48.7%). In those patients with optimal primary cytoreduction (n = 118), there was no survival advantage to second look (69% versus 61%, P = 0.7). However, in those with suboptimal primary cytoreduction (n = 47), 5-year survival was 36% in those having second look versus only 13% in those refusing second look (P < 0.05). Multivariate analysis identified second-look surgery as the only significant independent prognostic variable affecting survival (RR = 0.321, P < 0.04). Patients with suboptimal debulking at primary surgery for stage III ovarian cancer appear to achieve a survival benefit from second-look surgical procedures, presumably from the early identification and treatment of residual disease.

Laparoscopic second look operation for ovarian cancer: Single center experiences

2011 ◽  
Vol 20 (6) ◽  
pp. 346-351 ◽  
Author(s):  
Dae Gy Hong ◽  
Nae Yoon Park ◽  
Gun Oh Chong ◽  
Young Lae Cho ◽  
Il Soo Park ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Single Center ◽  
Second Look ◽  
Second Look Operation

scholarly journals Optimal Timing of a Second-Look Operation for Advanced Epithelial Ovarian Cancer.

1997 ◽  
Vol 44 (1) ◽  
pp. 15-21
Author(s):  
KIMIO USHIJIMA ◽  
TAKASHI NISHIDA ◽  
NAOFUMI OHKURA ◽  
TORU SUGIYAMA ◽  
KAN KOMAI ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Optimal Timing ◽  
Second Look ◽  
Advanced Epithelial Ovarian Cancer ◽  
Second Look Operation
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