scholarly journals Highly sensitive detection of sentinel lymph node metastasis of breast cancer by digital PCR for RASSF1A methylation

2019 ◽  
Author(s):  
Mizuho Abe ◽  
Naofumi Kagara ◽  
Tomohiro Miyake ◽  
Tomonori Tanei ◽  
Yasuto Naoi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Lymph Node Metastasis ◽  
Digital Pcr ◽  
Sensitive Detection ◽  
Node Metastasis ◽  
Rassf1a Methylation ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

scholarly journals Targeted axillary dissection in breast cancer by marking lymph node metastasis with a magnetic seed before starting neoadjuvant treatment

2019 ◽  
Vol 2019 (11) ◽  
Author(s):  
Joaquín Luis García-Moreno ◽  
Ana María Benjumeda-Gonzalez ◽  
Marta Amerigo-Góngora ◽  
Piero José Landra-Dulanto ◽  
Yisela Gonzalez-Corena ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Lymph Node Metastasis ◽  
Axillary Dissection ◽  
Neoadjuvant Treatment ◽  
Axillary Lymph Node Metastasis ◽  
Axillary Lymph ◽  
Node Metastasis ◽  
Magnetic Seeds

Abstract We report the first documented clinical case of the use of magnetic seeds to mark axillary lymph node metastasis in breast cancer before neoadjuvant chemotherapy. After chemotherapy, the patient showed a complete radiological response. One single sentinel lymph node was detected using a radiotracer, while the marked node was intraoperative magnetometer-guided identified. The analysis of the nodes showed negative sentinel lymph node and positive marked node, and the subsequent targeted axillary dissection was performed. Marking axillary positive lymph nodes with a magnetic seed is a simple and effective procedure for the intraoperative localisation of the node after neoadjuvant treatment.

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