scholarly journals Differential expression of filamin B splice variants in giant cell tumor cells

2016 ◽  
Vol 36 (6) ◽  
pp. 3181-3187
Author(s):  
Joseph Chi-Ching Tsui ◽  
Carol Po-Ying Lau ◽  
Alex Chun Cheung ◽  
Kwok-Chuen Wong ◽  
Lin Huang ◽  
...  
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Differential Expression ◽  
Tumor Cells ◽  
Splice Variants ◽  
Cell Tumor ◽  
Filamin B

scholarly journals Giant Cell Tumours of the Tendon Sheath – Particular MRI Aspect

2018 ◽  
Vol 1 (Supplement) ◽  
pp. 44
Author(s):  
A.M. Bratu ◽  
I.A. Sălcianu ◽  
A.I. Nicula ◽  
C. Zaharia ◽  
A.N. Marinescu
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Tumor Cells ◽  
Malignant Fibrous Histiocytoma ◽  
Fibrous Histiocytoma ◽  
Final Diagnosis ◽  
Tendon Sheath ◽  
Cell Tumor ◽  
Low Grade ◽  
Intravenous Contrast

Abstract Giant cell tumor of soft tissue (GCTST) is usually of synovial origin. It affects synovial membrane, serous bursae, and tendinous tunnels. The most common localizations are in the hands and forearms. Anatomopathological, GCTST is considered as being composed of a cellular fibroblastic stroma in which the tumor cells are distributed. This type of tumor is composed of a mononuclear complex and osteoclast-like giant multinucleated cells, similar to those found in the giant cell tumor at the bone level. Histologically, some authors consider that GCTST is a strictly benign tumor, consisting of welldefined multinucleated histiocytes admixed with eosinophils, lymphocytes and scattered spindleshaped cells, or hemosiderin deposits in its structure, and tumor cells do not have mitosis or atypia. Other authors consider that GCTST is a type of low-grade sarcoma; this entity was named “malignant fibrous histiocytoma, giant cell type” due to the histological similarity with malignant fibrous histiocytoma. The case of a female patient, suspected of giant cell tumor of the brachioradialis tendon sheath was presented. The MRI aspect of this tumor is not the typical one. The MRI examination consisted of a series of sequences, with T1 and T2 weighted images, fat suppression sequence, performed in all three planes, axial, sagittal, and coronal. Also, the examination was performed native, after the administration of intravenous contrast substance, when the 3D multiplanar sequences were performed. The final diagnosis was the post-operative anatomopathological examination, which confirmed that it was a giant cell tumor. We present this case for its less frequent localization - forearm, and the interest it might have in surgical treatment.

Bisphosphonates Induce Apoptosis of Stromal Tumor Cells in Giant Cell Tumor of Bone

2004 ◽  
Vol 75 (1) ◽  
pp. 71-77 ◽  
Author(s):  
Y. Y. Cheng ◽  
L. Huang ◽  
K. M. Lee ◽  
J. K. Xu ◽  
M. H. Zheng ◽  
...  
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Tumor Cells ◽  
Cell Tumor ◽  
Stromal Tumor

scholarly journals A landscape effect in tenosynovial giant-cell tumor from activation of CSF1 expression by a translocation in a minority of tumor cells

2006 ◽  
Vol 103 (3) ◽  
pp. 690-695 ◽  
Author(s):  
R. B. West ◽  
B. P. Rubin ◽  
M. A. Miller ◽  
S. Subramanian ◽  
G. Kaygusuz ◽  
...  
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Tumor Cells ◽  
Cell Tumor ◽  
Tenosynovial Giant Cell Tumor

Giant cell tumor of bone: Frequent actin immunoreactivity in stromal tumor cells

1997 ◽  
Vol 47 (10) ◽  
pp. 680-684 ◽  
Author(s):  
Kazuo Watanabe ◽  
Takahiro Tajino ◽  
Takashi Kusakabe ◽  
Atsuko Saitoh ◽  
Toshimitsu Suzuki
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Tumor Cells ◽  
Cell Tumor ◽  
Stromal Tumor

scholarly journals Differential Expression of ADAM23, CDKN2A (P16), MMP14 and VIM Associated with Giant Cell Tumor of Bone

2015 ◽  
Vol 6 (7) ◽  
pp. 593-603 ◽  
Author(s):  
André Luis Giacometti Conceição ◽  
Erica Babeto ◽  
Natalia Maria Candido ◽  
Fernanda Craveiro Franco ◽  
Débora Aparecida Pires de Campos Zuccari ◽  
...  
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Differential Expression ◽  
Cell Tumor
Sign in / Sign up

Export Citation Format

Share Document