scholarly journals Anti-metastatic effects of DNA vaccine encoding single-chain trimer composed of MHC I and vascular endothelial growth factor receptor 2 peptide

2015 ◽  
Vol 33 (5) ◽  
pp. 2269-2276 ◽  
Author(s):  
RUILING CHEN ◽  
SHENGCHAO WANG ◽  
YUNLIANG YAO ◽  
YUN ZHOU ◽  
CHONG ZHANG ◽  
...  
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Growth Factor ◽  
Dna Vaccine ◽  
Growth Factor Receptor ◽  
Vascular Endothelial ◽  
Single Chain ◽  
Mhc I ◽  
Endothelial Growth Factor

scholarly journals Identification of novel neutralizing single-chain antibodies against vascular endothelial growth factor receptor 2

2011 ◽  
Vol 58 (6) ◽  
pp. 412-422 ◽  
Author(s):  
Berrin Erdag ◽  
B. Koray Balcioglu ◽  
Aylin Ozdemir Bahadir ◽  
Muge Serhatli ◽  
Omer Kacar ◽  
...  
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Growth Factor ◽  
Growth Factor Receptor ◽  
Vascular Endothelial ◽  
Single Chain ◽  
Single Chain Antibodies ◽  
Endothelial Growth Factor

Fortgeschrittenes medulläres Schilddrüsenkarzinom: Vandetanib verbessert das progressionsfreie Überleben

2012 ◽  
Vol 03 (02) ◽  
pp. 93-92
Author(s):  
Alexander Kretzschmar
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Epidermal Growth Factor Receptor ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Growth Factor Receptor ◽  
Phase Iii ◽  
Vascular Endothelial ◽  
Medulläres Schilddrüsenkarzinom ◽  
Epidermal Growth ◽  
Endothelial Growth Factor

Vandetanib ist ein oraler Hemmer des RET-Kinase-, VEGF (Vascular Endothelial Growth Factor Receptor)- und EGFR (Epidermal Growth Factor Receptor)-Signalwegs. In einer zulassungsrelevanten, randomisierten, doppelblinden, placebokontrollierten Phase- III-Studie verlängerte der Tyrosinkinasehemmer das progressionsfreie Überleben (PFS) signifikant länger als Placebo.

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