scholarly journals A novel RET rearrangement (ACBD5/RET) by pericentric inversion, inv(10)(p12.1;q11.2), in papillary thyroid cancer from an atomic bomb survivor exposed to high-dose radiation

2014 ◽  
Vol 32 (5) ◽  
pp. 1809-1814 ◽  
Author(s):  
KIYOHIRO HAMATANI ◽  
HIDETAKA EGUCHI ◽  
KAZUAKI KOYAMA ◽  
MAYUMI MUKAI ◽  
KEI NAKACHI ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Papillary Thyroid Cancer ◽  
Pericentric Inversion ◽  
Atomic Bomb ◽  
High Dose ◽  
Atomic Bomb Survivor ◽  
Papillary Thyroid ◽  
Ret Rearrangement ◽  
Dose Radiation

Rearranged anaplastic lymphoma kinase (ALK) gene in adult-onset papillary thyroid cancer among atomic-bomb survivors

Thyroid ◽  
2012 ◽  
pp. 120622084931008
Author(s):  
Kiyohiro Hamatani ◽  
Mayumi Mukai ◽  
Keiko Takahashi ◽  
Yuzo Hayashi ◽  
Kei Nakachi ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Papillary Thyroid Cancer ◽  
Anaplastic Lymphoma Kinase ◽  
Atomic Bomb ◽  
Adult Onset ◽  
Papillary Thyroid ◽  
Atomic Bomb Survivors ◽  
Anaplastic Lymphoma ◽  
I Gene

scholarly journals Evaluation of Thyroglobulin Antibody Normalization in Papillary Thyroid Cancer Patients Receiving High-Dose I-131 Therapy

2021 ◽  
Author(s):  
Sang Hyun Hwang ◽  
KwanHyeong Jo ◽  
Chun Goo Kang ◽  
Jiyoung Wang ◽  
Hojin Cho ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Patients ◽  
Papillary Thyroid Cancer ◽  
Multivariable Analysis ◽  
Reduction Rate ◽  
Whole Body ◽  
High Dose ◽  
Papillary Thyroid ◽  
Thyroglobulin Antibody ◽  
Ablation Success

Abstract Purpose: Thyroglobulin antibody (TgAb) elevation after I-131 ablation may be difficult to evaluate in cases of recurrence, especially in high-risk patients. This study aimed to evaluate factors contributing to TgAb normalization in papillary thyroid cancer patients receiving high-dose I-131 therapy. Methods: From September 2009 to June 2012, 98 papillary thyroid cancer patients treated with 150 mCi radioactive iodine (RAI) were retrospectively enrolled. Early (3 day) and Delayed (7 day) post-RAI neck counts and reduction ratios were measured and correlated with clinical and pathologic findings. Patients with normal neck ultrasound and undetectable level of serum thyroglobulin (<0.1 ng/mL) and TgAb (<10 IU/mL) were defined as having successful ablation.Results: Thirty-five patients (35.7%) had thyroiditis and 28 (28.6%) achieved ablation success. The thyroiditis group had lower neck counts in both Early and Delayed whole-body scans (WBS), and higher reduction rates than the thyroiditis-absent group. In the ablation success group, Early and Delayed neck counts were significantly higher and the reduction rate of RAI was lower than those in the ablation failure group (p < 0.05). In multivariable analysis, Delayed neck count was the only significant factor for predicting ablation failure (odds ratio = 54.37, 95% confidence interval = 1.33-14.32; p = 0.015).Conclusion: I-131 uptake in the remnant thyroid gland and thyroiditis are factors that indicate TgAb normalization and ablation success in thyroid cancer patients receiving high-dose I-131 therapy.

scholarly journals RET/PTC Rearrangements Preferentially Occurred in Papillary Thyroid Cancer among Atomic Bomb Survivors Exposed to High Radiation Dose

2008 ◽  
Vol 68 (17) ◽  
pp. 7176-7182 ◽  
Author(s):  
Kiyohiro Hamatani ◽  
Hidetaka Eguchi ◽  
Reiko Ito ◽  
Mayumi Mukai ◽  
Keiko Takahashi ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Radiation Dose ◽  
Papillary Thyroid Cancer ◽  
Atomic Bomb ◽  
Papillary Thyroid ◽  
High Radiation ◽  
Atomic Bomb Survivors ◽  
High Radiation Dose

scholarly journals Rearranged Anaplastic Lymphoma Kinase (ALK) Gene in Adult-Onset Papillary Thyroid Cancer Amongst Atomic Bomb Survivors

Thyroid ◽  
2012 ◽  
Vol 22 (11) ◽  
pp. 1153-1159 ◽  
Author(s):  
Kiyohiro Hamatani ◽  
Mayumi Mukai ◽  
Keiko Takahashi ◽  
Yuzo Hayashi ◽  
Kei Nakachi ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Papillary Thyroid Cancer ◽  
Anaplastic Lymphoma Kinase ◽  
Atomic Bomb ◽  
Adult Onset ◽  
Papillary Thyroid ◽  
Atomic Bomb Survivors ◽  
Anaplastic Lymphoma
Sign in / Sign up

Export Citation Format

Share Document