scholarly journals Branched-chain amino acids suppress the cumulative recurrence of hepatocellular carcinoma under conditions of insulin-resistance

2013 ◽  
Vol 30 (2) ◽  
pp. 545-552 ◽  
Author(s):  
HITOSHI YOSHIJI ◽  
RYUICHI NOGUCHI ◽  
TADASHI NAMISAKI ◽  
KEI MORIYA ◽  
MITSUTERU KITADE ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Insulin Resistance ◽  
Amino Acids ◽  
Branched Chain Amino Acids ◽  
Branched Chain

Late-evening snack with branched-chain amino acids improves liver function after radiofrequency ablation for hepatocellular carcinoma

2012 ◽  
Vol 42 (7) ◽  
pp. 658-667 ◽  
Author(s):  
Daisuke Morihara ◽  
Kaoru Iwata ◽  
Takayuki Hanano ◽  
Hideo Kunimoto ◽  
Shizuka Kuno ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Amino Acids ◽  
Radiofrequency Ablation ◽  
Liver Function ◽  
Branched Chain Amino Acids ◽  
Late Evening ◽  
Branched Chain

Food consumption of branched chain amino acids and insulin resistance: A systematic review of observational studies in humans

2020 ◽  
Vol 40 ◽  
pp. 277-281
Author(s):  
Eduardo Emanuel Sátiro Vieira ◽  
Irislene Costa Pereira ◽  
Amanda Ferraz Braz ◽  
Marcus Vinicius Nascimento-Ferreira ◽  
Lucillia Rabelo de Oliveira Torres ◽  
...  
Keyword(s):  
Systematic Review ◽  
Insulin Resistance ◽  
Amino Acids ◽  
Food Consumption ◽  
Observational Studies ◽  
Branched Chain Amino Acids ◽  
Branched Chain

Insulin resistance and the metabolism of branched-chain amino acids

2013 ◽  
Vol 7 (1) ◽  
pp. 53-59 ◽  
Author(s):  
Jingyi Lu ◽  
Guoxiang Xie ◽  
Weiping Jia ◽  
Wei Jia
Keyword(s):  
Insulin Resistance ◽  
Amino Acids ◽  
Branched Chain Amino Acids ◽  
Branched Chain

Amino acid metabolism in the Zucker diabetic fatty rat: effects of insulin resistance and of type 2 diabetes

2004 ◽  
Vol 82 (7) ◽  
pp. 506-514 ◽  
Author(s):  
Enoka P Wijekoon ◽  
Craig Skinner ◽  
Margaret E Brosnan ◽  
John T Brosnan
Keyword(s):  
Insulin Resistance ◽  
Amino Acids ◽  
Amino Acid ◽  
Amino Acid Metabolism ◽  
Acid Metabolism ◽  
Plasma Concentrations ◽  
Branched Chain Amino Acids ◽  
Insulin Resistant ◽  
Branched Chain

We investigated amino acid metabolism in the Zucker diabetic fatty (ZDF Gmi fa/fa) rat during the prediabetic insulin-resistant stage and the frank type 2 diabetic stage. Amino acids were measured in plasma, liver, and skeletal muscle, and the ratios of plasma/liver and plasma/skeletal muscle were calculated. At the insulin-resistant stage, the plasma concentrations of the gluconeogenic amino acids aspartate, serine, glutamine, glycine, and histidine were decreased in the ZDF Gmi fa/fa rats, whereas taurine, α-aminoadipic acid, methionine, phenylalanine, tryptophan, and the 3 branched-chain amino acids were significantly increased. At the diabetic stage, a larger number of gluconeogenic amino acids had decreased plasma concentrations. The 3 branched-chain amino acids had elevated plasma concentrations. In the liver and the skeletal muscles, concentrations of many of the gluconeogenic amino acids were lower at both stages, whereas the levels of 1 or all of the branched-chain amino acids were elevated. These changes in amino acid concentrations are similar to changes seen in type 1 diabetes. It is evident that insulin resistance alone is capable of bringing about many of the changes in amino acid metabolism observed in type 2 diabetes.Key words: plasma amino acids, liver amino acids, muscle amino acids, gluconeogenesis.

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