scholarly journals Upregulation of miR-20a and miR-106b is involved in the acquisition of malignancy of pediatric brainstem gliomas

2012 ◽  
Vol 28 (4) ◽  
pp. 1293-1300 ◽  
Author(s):  
XUAN WANG ◽  
HONGWEI ZHANG ◽  
ANLING ZHANG ◽  
LEI HAN ◽  
KUN WANG ◽  
...  
Keyword(s):  
Pediatric Brainstem Gliomas

Gamma Knife radiosurgery as a treatment modality for low-grade pediatric brainstem gliomas: report of two cases

2011 ◽  
Vol 28 (1) ◽  
pp. 175-178 ◽  
Author(s):  
Chih-Hsiang Liao ◽  
David Hung-Chi Pan ◽  
Huai-Che Yang ◽  
Hsiu-Mei Wu ◽  
Donald Ming-Tak Ho ◽  
...  
Keyword(s):  
Gamma Knife ◽  
Treatment Modality ◽  
Gamma Knife Radiosurgery ◽  
Low Grade ◽  
Pediatric Brainstem Gliomas

scholarly journals Balloon-Assisted Superselective Intra-Arterial Cerebral Infusion of Bevacizumab for Malignant Brainstem Glioma

2010 ◽  
Vol 16 (1) ◽  
pp. 71-76 ◽  
Author(s):  
H.A. Riina ◽  
J. Knopman ◽  
J.P. Greenfield ◽  
S. Fralin ◽  
Y. P. Gobin ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Bowel Perforation ◽  
Treatment Options ◽  
Chemotherapeutic Agents ◽  
Brainstem Glioma ◽  
Tumor Site ◽  
Technical Report ◽  
Systemic Side Effects ◽  
First Time ◽  
Pediatric Brainstem Gliomas

Malignant brainstem gliomas (BSG) are rare tumors in adults, associated with a grim prognosis and limited treatment options. Currently, radiotherapy represents the mainstay of treatment, although new studies suggest an increased role for certain chemotherapeutic agents. Intravenous (IV) administration of bevacizumab (Avastin, Genentech Pharmaceuticals) has been shown to be active in the treatment of some enhancing malignant brainstem gliomas. The IV route of administration, however, carries a risk of systemic side effects such as bowel perforation, wound disrepair and pulmonary embolism. In addition, the percentage of IV drug that reaches the tumor site is restricted by the blood brain barrier (BBB). This technical report describes our protocol in performing superselective intra-arterial cerebral infusion (SIACI) of bevacizumab using endovascular balloon-assistance in the top of the basilar artery in a patient with a recurrent malignant brainstem glioma. It represents the first time such a technique has been performed for this disease. This method of drug delivery may have important implications in the treatment of both adult and pediatric brainstem gliomas.

scholarly journals Pediatric brainstem gliomas: An institutional experience

2019 ◽  
Vol 14 (4) ◽  
pp. 1144
Author(s):  
Ehsan Bari ◽  
AltafAli Laghari ◽  
MirzaZain Baig ◽  
Aneela Darbar ◽  
Naureen Mushtaq ◽  
...  
Keyword(s):  
Institutional Experience ◽  
Pediatric Brainstem Gliomas

scholarly journals HG-112LOCAL DELIVERY OF RADIOSENSITIZING NANOPARTICLES FOR THE TREATMENT OF PEDIATRIC BRAINSTEM GLIOMAS

2016 ◽  
Vol 18 (suppl 3) ◽  
pp. iii74.3-iii74
Author(s):  
Amanda King ◽  
Christopher Corso ◽  
Ranjit Bindra ◽  
W. Mark Saltzman
Keyword(s):  
Pediatric Brainstem Gliomas

Pediatric Brainstem Gliomas: A Retrospective Study of 180 Patients from the SEER Database

2019 ◽  
Vol 54 (3) ◽  
pp. 151-164 ◽  
Author(s):  
Syed I. Khalid ◽  
Ryan Kelly ◽  
Owoicho Adogwa ◽  
Adam Carlton ◽  
Edric Tam ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Seer Database ◽  
Pediatric Brainstem Gliomas

Gene Expression Profiling of Pediatric Brainstem Gliomas

Neurosurgery ◽  
2005 ◽  
Vol 57 (2) ◽  
pp. 417-417
Author(s):  
Ruth E. Bristol ◽  
Jessica Rennert ◽  
Stephen Coons ◽  
Michael Berens
Keyword(s):  
Gene Expression ◽  
Gene Expression Profiling ◽  
Expression Profiling ◽  
Pediatric Brainstem Gliomas
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