scholarly journals Cytokine-dependent invasiveness in B16 murine melanoma cells: Role of uPA system and MMP-9

2006 ◽  
Author(s):  
Francesca Bianchini ◽  
Silvia D'Alessio ◽  
Gabriella Fibbi ◽  
Mario Del Rosso ◽  
Lido Calorini
Keyword(s):  
Melanoma Cells ◽  
Murine Melanoma ◽  
Upa System ◽  
Murine Melanoma Cells

Expression of a metastatic phenotype in IFNs-primed/TNFα-activated B16 murine melanoma cells: role of JAK1/PKCδ signal transduction factors

2006 ◽  
Vol 23 (3-4) ◽  
pp. 203-208 ◽  
Author(s):  
Francesca Bianchini ◽  
Antonella Mannini ◽  
Gabriele Mugnai ◽  
Salvatore Ruggieri ◽  
Lido Calorini
Keyword(s):  
Signal Transduction ◽  
Melanoma Cells ◽  
Metastatic Phenotype ◽  
Murine Melanoma ◽  
Murine Melanoma Cells

Role of transglutaminase 2 in quercetin-induced differentiation of B16-F10 murine melanoma cells

Amino Acids ◽  
2008 ◽  
Vol 36 (4) ◽  
pp. 731-738 ◽  
Author(s):  
C. Forni ◽  
R. Braglia ◽  
A. Lentini ◽  
M. Nuccetelli ◽  
B. Provenzano ◽  
...  
Keyword(s):  
Transglutaminase 2 ◽  
Melanoma Cells ◽  
Induced Differentiation ◽  
Murine Melanoma ◽  
Murine Melanoma Cells

Role of asparagine-linked carbohydrates in pulmonary metastasis of B16-F10 murine melanoma cells

1992 ◽  
Vol 2 (1) ◽  
pp. 33-40 ◽  
Author(s):  
K. Tsukamoto ◽  
A. Uno ◽  
Y. Kubota ◽  
S. Shimada ◽  
Y. Hori ◽  
...  
Keyword(s):  
Pulmonary Metastasis ◽  
Melanoma Cells ◽  
Murine Melanoma ◽  
Murine Melanoma Cells

scholarly journals Anthocyanin determination in blueberry extracts from various cultivars and their antiproliferative and apoptotic properties in B16-F10 metastatic murine melanoma cells

2013 ◽  
Vol 95 ◽  
pp. 436-444 ◽  
Author(s):  
Andrea Bunea ◽  
Dumitriţa Rugină ◽  
Zoriţa Sconţa ◽  
Raluca M. Pop ◽  
Adela Pintea ◽  
...  
Keyword(s):  
Melanoma Cells ◽  
Murine Melanoma ◽  
Murine Melanoma Cells

Regulation of c-met expression in B16 murine melanoma cells by melanocyte stimulating hormone

1999 ◽  
Vol 112 (5) ◽  
pp. 623-630
Author(s):  
D. Rusciano ◽  
P. Lorenzoni ◽  
M.M. Burger
Keyword(s):  
Melanoma Cells ◽  
Parental Cell ◽  
Melanocortin Receptor ◽  
Parental Cell Line ◽  
Melanocyte Stimulating Hormone ◽  
Murine Melanoma ◽  
The One ◽  
Murine Melanoma Cells ◽  
Stimulating Hormone

B16 murine melanoma cells selected in vivo for enhanced liver metastatic ability (B16-LS9) show on the one hand an increased expression and constitutive activation of the proto-oncogene c-met (the receptor for hepatocyte growth factor/scatter factor), and on the other hand a more differentiated phenotype, when compared to the parental cell line, B16-F1. Following this observation, we have tried to establish whether there is a direct relationship between differentiation and c-met expression in B16 melanoma cells. Treatment of these cells with differentiating agents indicated that c-met expression was strongly induced by melanocyte stimulating hormone, while retinoic acid had almost no influence. c-met induction was triggered by engagement of the melanocortin receptor, cAMP elevation and PKA/PKC(α) activation, as respectively shown by the effects of ACTH, cAMP elevating agents and specific PK inhibitors. Regulation of c-met expression via the melanocortin receptor and cAMP raises the intriguing possibility that autocrine and/or paracrine mechanisms acting in vivo on this circuit might influence (through c-met expression and activation) the metastatic behavior of these tumor cells, which we have shown to be dependent on their c-met expression.

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