scholarly journals Comparison of long‑term treatment outcomes of T2N0M0 laryngeal squamous cell carcinoma using different treatment methods

2020 ◽  
Vol 20 (1) ◽  
pp. 921-930
Author(s):  
Eun Jung ◽  
Seong‑Min Jin ◽  
Jae‑Gu Kim ◽  
Jae‑Uk Jung ◽  
Dong Lee ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Treatment Outcomes ◽  
Squamous Cell ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Term Treatment ◽  
Treatment Methods ◽  
Long Term Treatment

Pigmented squamous cell carcinoma in an adolescent following long-term treatment with voriconazole

2016 ◽  
Vol 64 (4) ◽  
pp. e26280 ◽  
Author(s):  
J. Verdú-Amorós ◽  
J.-F. Wilbrand ◽  
P. Mayser ◽  
S. Gattenloehner ◽  
W. Woessmann
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Term Treatment ◽  
Long Term Treatment

Oral squamous cell carcinoma during long-term treatment with hydroxyurea

2004 ◽  
Vol 29 (6) ◽  
pp. 605-607 ◽  
Author(s):  
M. De Benedittis ◽  
M. Petruzzi ◽  
C. Giardina ◽  
L. Lo Muzio ◽  
G. Favia ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Term Treatment ◽  
Long Term Treatment

scholarly journals Expression of proliferation markers in laryngeal squamous cell carcinoma: an association with clinico-pathological factors and treatment outcomes

2020 ◽  
Vol 6 (5) ◽  
pp. 858
Author(s):  
Elizabeth Mathew Iype ◽  
Rajan Balakrishna ◽  
Lakshmi Subhadradevi ◽  
Jissa Vinoda Thulaseedharan ◽  
Bharath Veerabadhran ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Cyclin D1 ◽  
Treatment Outcomes ◽  
Squamous Cell ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Ki 67 ◽  
Proliferation Markers ◽  
Tissue Samples ◽  
Cyclin Dl

<p class="abstract"><strong>Background:</strong> The study was done with the objective to study the expression of epidermal growth factor receptor (EGFR), cyclin D1 and Ki-67 in laryngeal squamous cell carcinoma and to assess the correlation of all three proliferation markers with various clinic-pathological parameters, the treatment outcomes as well as survival.</p><p class="abstract"><strong>Methods:</strong> We prospectively evaluated the surgical specimens of 72 laryngeal squamous cell carcinoma (LSCC) patients, treated with primary surgery and post-operative adjuvant therapy. Tumor tissue samples were analysed for the expression of EGFR, cyclin D1 and Ki-67 markers and analysis were done by immune-histochemistry and western blot test.  </p><p class="abstract"><strong>Results:</strong> EGFR showed significant expression in 67.6% and was insignificant in 31.9% patients in our analysis of 72 tumor samples. Cyclin D1 showed intense expression in 43%, and was insignificant in 57% patients. Ki-67 was intensely expressed in 43% patients. There was no correlation between expression of these markers with age, T-stage and N-stage. However, all the three markers showed significantly intense expression in tumours with extra capsular disease as well as perineural invasion (PNI) both of which are features of invasiveness of the tumor.</p><p class="abstract"><strong>Conclusions:</strong> Estimation of biomarkers such as EGFR, cyclin Dl, and Ki-67 could be beneficial in predicting tumor aggressiveness, prognosis and survival in LSCC patients. Thus, all the three proliferation markers can be categorized as markers of invasiveness. Combination of proliferation markers-EGFR, cyclin D1 and Ki-67 is useful pre-operatively in planning surgical strategies so as to decide a more radical approach for the resection of the primary as well as neck dissection.</p>

Long-Term Treatment Outcomes for Heroin Dependence: The 11-Year Follow-Up of the ATOS Study

2013 ◽  
Author(s):  
Christina Marel ◽  
Maree Teesson ◽  
Shane Darke ◽  
Katherine Mills ◽  
Joanne Ross ◽  
...  
Keyword(s):  
Treatment Outcomes ◽  
Term Treatment ◽  
Heroin Dependence ◽  
Long Term Treatment
Sign in / Sign up

Export Citation Format

Share Document