scholarly journals Tanycytic ependymoma of filum terminale: Clinical characteristics and surgical outcomes

2018 ◽  
Author(s):  
Zonggang Hou ◽  
Xiaogang Tao ◽  
Junting Zhang ◽  
Zhen Wu ◽  
Baiyun Liu
2012 ◽  
Vol 187 (4S) ◽  
Author(s):  
Marc A. Bjurlin ◽  
Dae Y. Kim ◽  
Lee C. Zhao ◽  
Cristi J. Palmer ◽  
Courtney M.P. Hollowell

2016 ◽  
Vol 25 (12) ◽  
pp. 2048-2056 ◽  
Author(s):  
Jin-Young Park ◽  
Hyun-Yul Yoo ◽  
Seok Won Chung ◽  
Seung-Jun Lee ◽  
Na Ra Kim ◽  
...  

2022 ◽  
Vol 11 ◽  
Author(s):  
Rirong Qu ◽  
Fan Ye ◽  
Dehao Tu ◽  
Yixin Cai ◽  
Xiangning Fu

BackgroundWith the popularity of lung cancer screening and advances in imaging technology, more and more synchronous multiple primary lung adenocarcinomas (SMPLA) are being diagnosed clinically, however, the clinical characteristics and prognosis of SMPLA with different EGFR mutations remains unclear. We aimed to explore clinical features and surgical outcomes of these patients to aid in the diagnosis and treatment of SMPLA.MethodsMedical records of patients with different EGFR mutations who have been diagnosed as SMPLA and underwent surgical resection from March 2015 to December 2019 were retrospectively analyzed. Clinical characteristics, surgical outcomes, recurrence-free survival (RFS) and overall survival (OS) were investigated.ResultsA total of 70 patients (68.6% female and 77.1% non-somkers) were included. Total of 161 lesions in all patients, 84.4% were ground-glass opacity (GGO) lesions. EGFR mutations were detected in 108 lesions, most of which were L858R (35.4%) and 19Del (20.5%). The mutation rate of mixed GGO is significantly higher than that of pure GGO and solid nodules (SN); the mutation rate of invasive adenocarcinoma is significantly higher than that of other histology subtypes; the mutation rate of lesions >20 mm was significantly higher than that of ≤20 mm. However, there is no significant difference in the mutation rate of specific driver gene between different radiological features, pathological characteristics and sizes. After a median follow-up time of 29 months, the 3-year OS and RFS were 94.4% and 86.0%, respectively.ConclusionsA high discordance of EGFR mutations were identified between tumors in patients with SMPLA. Synchronous multiple lung adenocarcinomas with predominantly multiple GGO should be considered as SMPLA, and surgery may be aggressively performed for these patients due to a good prognosis.


2009 ◽  
Vol 46 (3) ◽  
pp. 160-167 ◽  
Author(s):  
Nan-Kai Wang ◽  
Tun-Lu Chen ◽  
Chi-Chun Lai ◽  
Ya-Hui Kuo ◽  
An-Ning Chao ◽  
...  

2020 ◽  
pp. 159101992096836
Author(s):  
Bikei Ryu ◽  
Shinsuke Sato ◽  
Tatsuki Mochizuki ◽  
Yasunari Niimi

A filum terminale arteriovenous fistula (FTAVF) is an extremely rare spinal arteriovenous fistula (AVF) and typically presents with myelopathy and conus medullaris syndrome caused by venous congestion in the spinal cord. Most reported FTAVFs are intradural pial AVFs with perimedullary drainage in the filum terminale interna. However, there are no reports of AVFs in the filum terminale externa (FTE). We describe a case involving a 68-year-old man with an AVF in the FTE who presented with progressive myelopathy and underwent successful endovascular treatment. We identified the specific shunt point by fusing postoperative computed tomography and magnetic resonance images. The features of the extradural sac AVF developed in the FTE may mimic those of a dural AVF with dural supply to the FTE covered by the dural component, unlike typical FTAVFs where the shunt develops at the pia mater. This case makes a significant contribution to the field by increasing the understanding of the clinical characteristics of an AVF that develops in the FTE and its angioarchitecture.


2020 ◽  
pp. 019459982097543
Author(s):  
Zhenzhen Zhu ◽  
Weibo Xia ◽  
Fang Qi ◽  
Weiqing Wang ◽  
Xiaowei Wang ◽  
...  

Objective To investigate the clinical characteristics and surgical outcomes of sinonasal tumors associated with tumor-induced osteomalacia (TIO). Study Design Retrospective case series. Setting Single tertiary center. Methods We studied the clinical characteristics and surgical outcomes of 43 patients (22 male, 21 female) who had lesions in the nasal cavity and paranasal sinus associated with TIO and underwent surgery between August 2006 and November 2019. Results The mean ± SD duration between the onset of symptoms and surgery was 3.9 ± 2.6 years. The most common tumor site was the ethmoid sinus (76.7%), and the skull base was involved in 12 cases. Phosphaturic mesenchymal tumors were diagnosed in 41 patients, among whom there was 1 multifocal case. Another 2 cases involved odontogenic fibroma and hemangiofibroma, respectively. Serum phosphorus normalized in 39 cases within 4.4 ± 2.3 days, and serum fibroblastic growth factor 23 normalized within 1 day; clinical symptoms, however, gradually improved within several months after the first operation. There was no significant difference in the recovery rate between endoscopic and open surgery ( P = 0.639). Two patients with recurrent cases and 2 with nonremission cases recovered after a sinonasal reoperation. The patient with a multifocal case recovered after the resection of the tumors in the ethmoid sinus and mandible. The overall recovery rate was 97.7%. Conclusion Most sinonasal tumors associated with TIO are located in the ethmoid sinus, and the skull base is involved in some cases. Complete excision of the tumor leads to recovery, and endoscopic surgery could achieve recovery rates similar to those of open surgery.


2017 ◽  
Vol 31 (1) ◽  
pp. 93-95
Author(s):  
Atsufumi Nagahama ◽  
Kentaro Naito ◽  
Toru Yamagata ◽  
Kenji Ohata ◽  
Toshihiro Takami

2013 ◽  
Vol 156 (2) ◽  
pp. 269-275 ◽  
Author(s):  
Tao Yang ◽  
Liang Wu ◽  
Xiaofeng Deng ◽  
Chenlong Yang ◽  
Jingyi Fang ◽  
...  

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