scholarly journals Differential expression profiles of microRNAs in highly and weakly invasive/metastatic pancreatic cancer cells

2018 ◽  
Author(s):  
Xiaodong Tan ◽  
Lei Zhou ◽  
Huaitao Wang ◽  
Yifan Yang ◽  
Yang Sun ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Cells ◽  
Differential Expression ◽  
Expression Profiles ◽  
Metastatic Pancreatic Cancer ◽  
Pancreatic Cancer Cells

scholarly journals mRNA expression profiles obtained from microdissected pancreatic cancer cells can predict patient survival

Oncotarget ◽  
2017 ◽  
Vol 8 (62) ◽  
pp. 104796-104805
Author(s):  
Ana-Barbara García-García ◽  
M. Carmen Gómez-Mateo ◽  
Rebeca Hilario ◽  
Pilar Rentero-Garrido ◽  
Alvaro Martínez-Domenech ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Mrna Expression ◽  
Cancer Cells ◽  
Patient Survival ◽  
Expression Profiles ◽  
Pancreatic Cancer Cells

Primary and Metastatic Pancreatic Cancer Cells Exhibit Differential Migratory Potentials

Pancreas ◽  
2020 ◽  
Vol 49 (1) ◽  
pp. 128-134
Author(s):  
Joo Kyung Park ◽  
Thomas Hank ◽  
Cally M. Scherber ◽  
Keith D. Lillemoe ◽  
Carlos Fernández-del Castillo ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Cells ◽  
Metastatic Pancreatic Cancer ◽  
Pancreatic Cancer Cells

scholarly journals Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells

2008 ◽  
Vol 7 (3) ◽  
pp. 464-473 ◽  
Author(s):  
Michael Sun ◽  
Zeev Estrov ◽  
Yuan Ji ◽  
Kevin R. Coombes ◽  
David H. Harris ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Cells ◽  
Expression Profiles ◽  
Human Pancreatic Cancer ◽  
Pancreatic Cancer Cells

Metformin alters the expression profiles of microRNAs in human pancreatic cancer cells

2012 ◽  
Vol 96 (2) ◽  
pp. 187-195 ◽  
Author(s):  
Weiguang Li ◽  
Yaozong Yuan ◽  
Liya Huang ◽  
Minmin Qiao ◽  
Yongping Zhang
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Cells ◽  
Expression Profiles ◽  
Human Pancreatic Cancer ◽  
Pancreatic Cancer Cells

scholarly journals Highly lymphatic metastatic pancreatic cancer cells possess stem cell-like properties

2013 ◽  
Vol 42 (3) ◽  
pp. 979-984 ◽  
Author(s):  
GUOPEI LUO ◽  
JIANG LONG ◽  
XIAOBO CUI ◽  
ZHIWEN XIAO ◽  
ZUQIANG LIU ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Stem Cell ◽  
Cancer Cells ◽  
Metastatic Pancreatic Cancer ◽  
Pancreatic Cancer Cells

scholarly journals DUSP28 is a novel biomarker responsible for aggravating malignancy via the autocrine signaling pathways in metastatic pancreatic cancer

2018 ◽  
Author(s):  
Jungwhoi Lee ◽  
Jungsul Lee ◽  
Chulhee Choi ◽  
Jae Hoon Kim
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Cells ◽  
Signaling Pathways ◽  
Umbilical Vein ◽  
Metastatic Pancreatic Cancer ◽  
Autocrine Signaling ◽  
Pancreatic Cancer Cells ◽  
Promising Therapeutic Target ◽  
Umbilical Vein Endothelial Cells

AbstractPancreatic cancer remains one of the most dangerous cancers with a grave prognosis. We previously reported that pancreatic cancer cells can secrete dual specificity phosphatise 28 (DUSP28) to the cultured medium. However, its biological function is poorly understood. Here, we have identified the function of DUSP28 in human metastatic pancreatic cancer. Treatment with recombinant DUSP28 (rDUSP28) significantly increased the migration, invasion, and viability of metastatic pancreatic cancer cells through the activation of CREB, AKT, and ERK1/2 signaling pathways. Furthermore, rDUSP28 acted as an oncogenic reagent through the interaction with integrin α1 in metastatic pancreatic cancer cells. In addition, rDUSP28 induced pro-angiogenic effects in human umbilical vein endothelial cells (HUVECs). Administration of rDUSP28 also produced tumor growth in vivo. Notably, sDUSP28 can easily be detected by immunoassay. The results establish the rationale for sDUSP28 as a promising therapeutic target and biomarker for metastatic pancreatic cancer patients.

Transcriptional profile of metastatic pancreatic cancer cells

2001 ◽  
Vol 120 (5) ◽  
pp. A339-A339
Author(s):  
P MICHL ◽  
M BUCHHOLZ ◽  
H OEZDEMIR ◽  
K KALMBACH ◽  
T GRESS
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Cells ◽  
Transcriptional Profile ◽  
Metastatic Pancreatic Cancer ◽  
Pancreatic Cancer Cells

Transcriptional profile of metastatic pancreatic cancer cells

2001 ◽  
Vol 120 (5) ◽  
pp. A339
Author(s):  
Patrick Michl ◽  
Malte Buchholz ◽  
Hicran Oezdemir ◽  
Karolin Kalmbach ◽  
Thomas M. Gress
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Cells ◽  
Transcriptional Profile ◽  
Metastatic Pancreatic Cancer ◽  
Pancreatic Cancer Cells
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