scholarly journals LncRNA BX357664 inhibits cell proliferation and invasion and promotes cell apoptosis in human colorectal cancer cells

2018 ◽  
Author(s):  
Fengjun Liu ◽  
Xinsheng Wang ◽  
Haiyan Liu ◽  
Yang Wang ◽  
Xiaoqian Liu ◽  
...  
2017 ◽  
Vol 8 (2) ◽  
pp. 1062-1067 ◽  
Author(s):  
H. Qian ◽  
C. Y. Tay ◽  
M. I. Setyawati ◽  
S. L. Chia ◽  
D. S. Lee ◽  
...  

A DNA nanostructure bearing a “Shuriken” shape is designed to deliver, protect and activate microRNA-145 functionality in human colorectal cancer cells. This novel DNA nanostructure enabled therapeutic platform greatly suppresses cancer cell proliferation and tumor growth.


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