scholarly journals A retrospective study of pattern of recurrence after radical surgery for thoracic esophageal carcinoma with or without postoperative radiotherapy

2018 ◽  
Author(s):  
Yichun Wang ◽  
Li Zhang ◽  
Dongmei Ye ◽  
Wanli Xia ◽  
Jun Jiang ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Esophageal Carcinoma ◽  
Radical Surgery ◽  
Postoperative Radiotherapy ◽  
Pattern Of Recurrence

Reevaluation of postoperative radiotherapy for thoracic esophageal carcinoma

1997 ◽  
Vol 37 (1) ◽  
pp. 75-78 ◽  
Author(s):  
Michinori Yamamoto ◽  
Takashi Yamashita ◽  
Toshiki Matsubara ◽  
Tadashi Kitahara ◽  
Kenji Sekiguchi ◽  
...  
Keyword(s):  
Esophageal Carcinoma ◽  
Postoperative Radiotherapy

scholarly journals Pattern of recurrence of pN2 non-small-cell lung cancer: should postoperative radiotherapy be reconsidered?

2020 ◽  
Vol 59 (1) ◽  
pp. 109-115 ◽  
Author(s):  
Kazuo Nakagawa ◽  
Yukihiro Yoshida ◽  
Masaya Yotsukura ◽  
Shun-ichi Watanabe
Keyword(s):  
Lung Cancer ◽  
Adjuvant Chemotherapy ◽  
Small Cell Lung Cancer ◽  
Postoperative Radiotherapy ◽  
Distant Recurrence ◽  
Small Cell ◽  
Small Cell Lung ◽  
Nodal Dissection ◽  
Systematic Nodal Dissection ◽  
Pattern Of Recurrence

Abstract OBJECTIVES The prognosis of patients with mediastinal lymph node (LN) metastasis (pN2 stage III disease) is still unsatisfactory. Both systemic and local recurrence should be prevented after curative surgery. The aim of this study was to explore the pattern of recurrence in patients with completely resected pN2 non-small-cell lung cancer (NSCLC) in the era of adjuvant chemotherapy. METHODS We investigated 337 patients with completely resected cN0-1 and pN2 NSCLC from 2005 to 2016 at National Cancer Center Hospital, Japan. The patterns of recurrence were compared between patients who were managed by observation alone and those with adjuvant chemotherapy. In patients with regional LN recurrence, the pattern and site of recurrence were also explored. RESULTS There were 195 (58.5%) men and 142 (41.5%) women with a mean age of 63.2 years. Fifty-five (16.3%) patients developed only regional LN recurrence, 116 (32.6%) patients developed only distant recurrence and 65 (19.3%) patients developed both regional LN recurrence and distant recurrence. The difference in the pattern of recurrence between patients with observation alone and those with adjuvant chemotherapy was not statistically significant (P = 0.145). As for the pattern of regional LN recurrence, 68 (20.2%) patients had LN recurrence inside the systematic nodal dissection area. CONCLUSIONS Regional LN recurrence was observed in >30% of patients with completely resected pN2 NSCLC. About 20% of patients had recurrence inside the systematic nodal dissection area. Postoperative radiotherapy might be considered as an additional treatment strategy for these patients.

A meta-analysis on surgery with or without postoperative radiotherapy to treat squamous cell esophageal carcinoma

2020 ◽  
Vol 80 ◽  
pp. 184-191 ◽  
Author(s):  
Hao-Nan Lin ◽  
Long-Qi Chen ◽  
Qi-Xin Shang ◽  
Yong Yuan ◽  
Yu-Shang Yang
Keyword(s):  
Esophageal Carcinoma ◽  
Squamous Cell ◽  
Postoperative Radiotherapy ◽  
Meta Analysis
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