scholarly journals TNF-α promotes colon cancer cell migration and invasion by upregulating TROP-2

2018 ◽  
Author(s):  
Peng Zhao ◽  
Zhongtao Zhang
Keyword(s):  
Colon Cancer ◽  
Cell Migration ◽  
Cancer Cell ◽  
Colon Cancer Cell ◽  
Migration And Invasion ◽  
Cancer Cell Migration ◽  
Cell Migration And Invasion ◽  
Tnf Α

scholarly journals Verticillin A inhibits colon cancer cell migration and invasion by targeting c-Met

2020 ◽  
Vol 21 (10) ◽  
pp. 779-795
Author(s):  
Qian-qian Liu ◽  
Xue-li Zeng ◽  
Yue-lin Guan ◽  
Jing-xin Lu ◽  
Kai Tu ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Cell Migration ◽  
Cancer Cell ◽  
Colon Cancer Cell ◽  
Migration And Invasion ◽  
Cancer Cell Migration ◽  
Cell Migration And Invasion

Regulation of colon cancer cell migration and invasion by CLIC1-mediated RVD

2012 ◽  
Vol 365 (1-2) ◽  
pp. 313-321 ◽  
Author(s):  
Pan Wang ◽  
Chao Zhang ◽  
PeiWu Yu ◽  
Bo Tang ◽  
Tao Liu ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Cell Migration ◽  
Cancer Cell ◽  
Colon Cancer Cell ◽  
Migration And Invasion ◽  
Cancer Cell Migration ◽  
Cell Migration And Invasion

scholarly journals Targeting FHL2‑E‑cadherin axis by miR‑340‑5p attenuates colon cancer cell migration and invasion

2021 ◽  
Vol 22 (2) ◽  
Author(s):  
Anwar Algaber ◽  
Raed Madhi ◽  
Avin Hawez ◽  
Carl-Fredrik Rönnow ◽  
Milladur Rahman
Keyword(s):  
Colon Cancer ◽  
Cell Migration ◽  
Cancer Cell ◽  
Colon Cancer Cell ◽  
Migration And Invasion ◽  
Cancer Cell Migration ◽  
Cell Migration And Invasion ◽  
E Cadherin

scholarly journals MicroRNA-340-5p inhibits colon cancer cell migration via targeting of RhoA

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Anwar Algaber ◽  
Amr Al-Haidari ◽  
Raed Madhi ◽  
Milladur Rahman ◽  
Ingvar Syk ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Cell Migration ◽  
Cancer Cell ◽  
Colon Cancer Cell ◽  
Migration And Invasion ◽  
Cancer Cell Migration ◽  
Colon Cancer Cells ◽  
Cell Migration And Invasion ◽  
Ht 29

Abstract Colon cancer is the third most common cancer and a significant cause of cancer-related deaths worldwide. Metastasis is the most insidious aspect of cancer progression. Convincing data suggest that microRNAs (miRs) play a key function in colon cancer biology. We examined the role of miR-340-5p in regulating RhoA expression as well as cell migration and invasion in colon cancer cells. Levels of miR-340-5p and RhoA mRNA varied inversely in serum-free and serum-grown HT-29 and AZ-97 colon cancer cells. It was found transfection with miR-340-5p not only decreased expression of RhoA mRNA and protein levels in HT-29 cells but also reduced colon cancer cell migration and invasion. Bioinformatics analysis predicted one putative binding sites at the 3′-UTR of RhoA mRNA. Targeting this binding site with a specific blocker reversed mimic miR-340-5p-induced inhibition of RhoA activation and colon cancer cell migration and invasion. These novel results suggest that miR-340-5p is an important regulator of colon cancer cell motility via targeting of RhoA and further experiments are warranted to evaluate the role of miR-340-5p in colon cancer metastasis.

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