scholarly journals Prognostic value of Rho GDP dissociation inhibitors in patients with hepatocellular carcinoma following liver transplantation

2017 ◽  
Vol 14 (2) ◽  
pp. 1395-1402
Author(s):  
Ming-Chun Lai ◽  
Qian-Qian Zhu ◽  
Kwabena-Gyabaah Owusu-Ansah ◽  
Yang-Bo Zhu ◽  
Zhe Yang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Transplantation ◽  
Prognostic Value

scholarly journals Prognostic Value of Serum Caspase-Cleaved Cytokeratin-18 Levels before Liver Transplantation for One-Year Survival of Patients with Hepatocellular Carcinoma

2016 ◽  
Vol 17 (9) ◽  
pp. 1524 ◽  
Author(s):  
Leonardo Lorente ◽  
Sergio Rodriguez ◽  
Pablo Sanz ◽  
Antonia Pérez-Cejas ◽  
Javier Padilla ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Transplantation ◽  
Prognostic Value ◽  
Cytokeratin 18 ◽  
One Year

scholarly journals Prognostic Value of Albumin-to-Alkaline Phosphatase Ratio in Hepatocellular Carcinoma Patients Treated with Liver Transplantation

2020 ◽  
Vol 11 (8) ◽  
pp. 2171-2180 ◽  
Author(s):  
Hui Li ◽  
Li Wang ◽  
Liang Chen ◽  
Hui Zhao ◽  
Jianye Cai ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Transplantation ◽  
Alkaline Phosphatase ◽  
Prognostic Value

scholarly journals Systemic Immune-Inflammation Index (SII) is Useful to Predict Survival Outcomes in Patients After Liver Transplantation for Hepatocellular Carcinoma within Hangzhou Criteria

2018 ◽  
Vol 47 (1) ◽  
pp. 293-301 ◽  
Author(s):  
Hongyuan Fu ◽  
Jun Zheng ◽  
Jianye Cai ◽  
Kaining Zeng ◽  
Jia Yao ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Transplantation ◽  
Roc Curve ◽  
Prognostic Value ◽  
Proportional Hazards Model ◽  
Prognostic Biomarker ◽  
Cox Proportional Hazards Model ◽  
Roc Curve Analysis ◽  
Lymphocyte Ratio ◽  
Immune Inflammation

Background: There is growing evidence that the systemic immune-inflammation index (SII), a novel prognostic biomarker based on peripheral lymphocyte, neutrophil, and platelet counts, is associated with poor prognosis for several tumors. However, the prognostic value of SII in patients with hepatocellular carcinoma (HCC) who undergo liver transplantation (LT) remains unclear. The aim of this study was to determine the correlation between SII and prognosis in these patients. Methods: This retrospective study involved 150 patients with HCC who underwent LT within the Hangzhou criteria. The optimal cut-off value was determined by receiver-operating characteristic (ROC) curve analysis to stratify the patients into those with a high SII and those with low SII. The Kaplan-Meier method and the Cox proportional hazards model were used to evaluate the prognostic value of SII. Finally, we calculated the area under the ROC curve to compare the prognostic power of SII, platelet-to-lymphocyte ratio (PLR), neutrophil-to-lymphocyte ratio (NLR), and monocyte-to-lymphocyte ratio (MLR). Results: Patients were divided into high SII (≥ 226) and low SII (< 226) groups. Five-year overall survival (OS) was lower in the high SII group than in the low SII group (56.1% vs. 82.4%, p = 0.002). SII ≥ 226 × 109/L, maximum tumor size> 5 cm, microvascular invasion, and poor differentiation were independent prognostic factors for OS. However, SII did not predict 5-year recurrence-free survival (high vs. low SII: 64.1% vs. 78.4%, p = 0.073). The area under the ROC curve was greater for SII than for PLR, NLR, and MLR. Conclusions: Preoperative SII may be a powerful prognostic biomarker in patients with HCC who undergo LT within the Hangzhou criteria. SII is superior to PLR, NLR, and MLR for prediction of OS in these patients.

Prognostic value of preoperative peripheral monocyte count in patients with hepatocellular carcinoma after liver transplantation

Tumor Biology ◽  
2016 ◽  
Vol 37 (7) ◽  
pp. 8973-8978 ◽  
Author(s):  
Qing-Qi Ren ◽  
Shun-Jun Fu ◽  
Qiang Zhao ◽  
Zhi-Yong Guo ◽  
Fei Ji ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Transplantation ◽  
Prognostic Value ◽  
Monocyte Count ◽  
Peripheral Monocyte
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