scholarly journals Clinical features and surgical management of intracranial meningiomas in the elderly

2017 ◽  
Vol 14 (1) ◽  
pp. 909-917 ◽  
Author(s):  
Junkoh Yamamoto ◽  
Mayu Takahashi ◽  
Masaru Idei ◽  
Yoshiteru Nakano ◽  
Yoshiteru Soejima ◽  
...  
1997 ◽  
Vol 26 (suppl 1) ◽  
pp. P44-P44
Author(s):  
D.M. Beaumont ◽  
M. Mian

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 926.1-926
Author(s):  
M. Mrabet ◽  
S. Boussaid ◽  
S. Jemmali ◽  
H. Sahli ◽  
H. Ajlani ◽  
...  

Background:Tuberculosis is still endemic all over the world. The incidence of tuberculous spondylodiscitis (TS) is steadily increasing. Clinical features and outcomes of this affection are various and depending on various parameters, including age.Objectives:Our objective was to explore the differences in presentation and the results of further investigations and the prognosis of TS between young and elderly subjects.Methods:We conduct a retrospective and descriptive study in a single rheumatology department. Data were collected from files of patients hospitalized in the past 20 years (2000-2020) who have been diagnosed with TS. We carried out a comparative study concerning the clinical biological, imaging features and outcomes between young subjects and subjects aged over 65 years.Results:Fifty-two cases of TS were collected (37F/15M). The mean age of the population was 55.21 years ± 17.79 [19-91]. Thirty-three patients (69.2%) were classified as young versus 16 elderly patients (30.8%), with female predominance in both groups (69.4% and 75% respectively, p = 0.57). Young subjects was more frequently vaccinated (88.9%) by Bacillus Calmette–Guérin (BCG) (p < 0.001). A delayed diagnosis was noted in both groups (p = 0.24). Lumbar spine involvement was the most common (57.7%). In the two age ranges, the onset of the disease was progressive (p = 0.22), characterized by segmental spine stiffness (p = 0.57) and lumbar pain with general signs (p = 0.27), such as: impaired general condition, fever, night sweats and weight loss. Biological inflammatory syndrome and normochrome normocytic anemia were encountered in both cases (p = 0.08 and p = 0.2, respectively). Standard X-rays and Computed tomography were more performed in young subjects (94.4% and 69.4%, respectively; p < 0.001), unlike magnetic resonance imaging which was more common in elderly subjects but with no statistically significant difference (p = 0.22). Disc pinch, erosion of vertebral plateaus and vertebral collapse were the major signs (82.7%, 65.4% and 67.3%, respectively). Clinical, biological and imaging arguments contributed to positive diagnosis in both groups (p = 0.24). Common medical treatment was anti-tuberculosis: Isoniazid (H), Rifampicin (R), Pyrazinamide (Z), Ethambutol (E) and physical treatment such as immobilization witch was more common in the eldery (56.3%, p = 0.16). The evolution of the disease was characterized by a clear improvement of young subjects during the second week of treatment (p < 0.001). A more frequent clinical improvement in older subjects was during the fourth week but with no statistically significant difference (p = 0.13). The occurrence of immediate complications was more frequent in the elderly (p = 0.23) with a predominance for drug complications (56.3%) such as: hepatic cytolysis (12.5%), hyperuricemia (18.8%) and major intolerance to anti-tuberculosis (18.8%).Conclusion:TS is a frequent condition that needs to be treated rapidly. the clinical presentation of TS in the elderly is less noisy which leads to more frequent complications and mortality.Disclosure of Interests:None declared


2010 ◽  
Vol 24 (5) ◽  
pp. 694.e5-694.e8 ◽  
Author(s):  
Chika Cho ◽  
Raphael Coscas ◽  
Fabien Koskas

1998 ◽  
pp. 91-96
Author(s):  
G. Abate ◽  
M. Zito ◽  
A. Di Iorio

2006 ◽  
Vol 443 (&NA;) ◽  
pp. 140-145 ◽  
Author(s):  
Hideki Nagashima ◽  
Yasuo Morio ◽  
Hideki Yamashita ◽  
Koji Yamane ◽  
Ryota Teshima

F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 1793
Author(s):  
Emily J. Guerard ◽  
Gil E. Harmon ◽  
Kieran D. Sahasrabudhe ◽  
Noelle K. LoConte

This article summarizes the seminal publications from mid-2016 through 2017 in the area of medical care for older adults with cancer. Areas addressed include chemotherapy tolerance and efficacy in the aged, geriatric fitness assessments, and advancements in palliative and supportive care. The practice-changing finding from this past year’s publications is that antipsychotics should not be used in the management of terminal delirium in older adults receiving palliative care. The other trials demonstrated an improved understanding of the utility of geriatric assessments in patients with cancer, developed the body of information about which chemotherapy agents are safe and effective in older adults (and which are not), and expanded our understanding of good palliative and supportive care.


1996 ◽  
pp. 153-160 ◽  
Author(s):  
S. Kuzuhara ◽  
M. Yoshimura ◽  
T. Mizutani ◽  
H. Yamanouchi ◽  
Y. Ihara

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