scholarly journals Recombinant fibromodulin and decorin effects on NF-κB and TGFβ1 in the 4T1 breast cancer cell line

2017 ◽  
Vol 13 (6) ◽  
pp. 4475-4480 ◽  
Author(s):  
Ladan Dawoody Nejad ◽  
Alireza Biglari ◽  
Tiziana Annese ◽  
Domenico Ribatti
Keyword(s):  
Breast Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Cancer Cell Line ◽  
4T1 Breast Cancer

Neuropeptide Y stimulates proliferation and migration in the 4T1 breast cancer cell line

2011 ◽  
Vol 131 (2) ◽  
pp. 276-286 ◽  
Author(s):  
Philip J. Medeiros ◽  
Baraa K. Al-Khazraji ◽  
Nicole M. Novielli ◽  
Lynne M. Postovit ◽  
Ann F. Chambers ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Neuropeptide Y ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Cancer Cell Line ◽  
4T1 Breast Cancer ◽  
And Migration ◽  
Proliferation And Migration

Anticancer tendency of aflatoxin B1 in 4T1 breast cancer cell line

Gene Reports ◽  
2019 ◽  
Vol 16 ◽  
pp. 100442 ◽  
Author(s):  
Roya Mousazadeh ◽  
Saeed Hesaraki ◽  
Mansour Bayat ◽  
Alireza Jahandideh ◽  
Jamal Hashemi
Keyword(s):  
Breast Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Aflatoxin B1 ◽  
Cancer Cell Line ◽  
4T1 Breast Cancer

A proteomic analysis of p53-independent induction of apoptosis by bortezomib in 4T1 breast cancer cell line

2015 ◽  
Vol 113 ◽  
pp. 315-325 ◽  
Author(s):  
Azmi Yerlikaya ◽  
Emrah Okur ◽  
Ahmet Tarık Baykal ◽  
Ceyda Acılan ◽  
İhsan Boyacı ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Proteomic Analysis ◽  
Cancer Cell Line ◽  
Induction Of Apoptosis ◽  
4T1 Breast Cancer

Effect of Ginger Extract on 4T1 Breast Cancer cell line in Balb/c Mouse.

2021 ◽  
Vol 08 ◽  
Author(s):  
Alireza Pooyae Golizadeh ◽  
Asa Ebrahimi ◽  
Mahdi Rahaie ◽  
Farzaneh Samiee
Keyword(s):  
Breast Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Day Treatment ◽  
Cancer Cell Line ◽  
Ginger Extract ◽  
Suppressor Genes ◽  
4T1 Breast Cancer

Background: By considering [6]-gingerol as an important polyphenol, ginger has been identified to be related to cancer. Objective: In this study, the evaluation of ginger extract on the expressions of four genes from different categories involved in breast cancer process in Balb/C mouse after 14 days was the main objective. Methods: In term of this research, ethanol extraction methods for extracting ginger rhizomes with the goal of increasing [6]-gingerol were used. In this regard, MTT test was accomplished for whole ginger extract to confirm its effect on 4T1 breast cancer cell line (murine mammary carcinoma cell). Afterward, the transplanted breast cancer Balb/C mouse was used to be treated by whole ginger extract (0.02 g/kg of mouse weight). The expressions of STAT3, β-catenin, P53, APC, genes were evaluated, after 14-day treatment. Results: The results showed that 70% ethanol and microwave extraction method can be considered as the best method for extracting ginger extract. The results of the expression of β-catenin has decreased in blood and liver of the treated group. Moreover, the expression of STAT3 oncogenes has significantly decreased in the liver tissue. In addition, the expressions of APC suppressor genes have increased in Blood and liver. Conclusion: In conclusion, treatment by 0.02 g/kg of mouse weight of ginger extract after 14 days increased the expressions of APC as suppressor genes and β-catenin oncogene in Blood and liver of the breast cancer group.

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