scholarly journals Complete response to capecitabine in a frail, elderly patient with metastatic colorectal cancer: A case report

2016 ◽  
Vol 13 (2) ◽  
pp. 979-983
Author(s):  
Morena Fasano ◽  
Alessio Fabozzi ◽  
Guido Giordano ◽  
Filippo Venturini ◽  
Gaetano Aurilio ◽  
...  
2016 ◽  
Vol 7 (4) ◽  
pp. 364-365 ◽  
Author(s):  
S.-J. Yoon ◽  
J.-Y. Choi ◽  
S.-W. Kim ◽  
E.-S. Jang ◽  
K.-S. Lee ◽  
...  

2018 ◽  
Vol 11 (2) ◽  
pp. 461-466
Author(s):  
Masatsune Shibutani ◽  
Kiyoshi Maeda ◽  
Hisashi Nagahara ◽  
Tatsunari Fukuoka ◽  
Yasuhito Iseki ◽  
...  

As a result of recent major advances in chemotherapy for metastatic colorectal cancer, the prognosis for patients with metastatic colorectal cancer has improved. However, elderly patients often cannot receive intensive therapy. There are still many problems to solve regarding treatment for elderly patients with metastatic colorectal cancer. We herein report a case of complete response of pulmonary metastases from rectal cancer to tegafur-uracil (UFT)/leucovorin (LV) + bevacizumab (Bmab) in an elderly patient. An 80-year-old woman who had undergone curative surgery for rectal cancer 5 years ago was diagnosed with pulmonary metastases. Taking into account her advanced age and low renal function (creatinine clearance: 41.2 mL/min), UFT/LV + Bmab therapy was selected. The patient received UFT (300 mg/m2/day) and LV (75 mg/day) on days 1–5, 8–12, and 15–19 and Bmab (7.5 mg/kg) on day 1. The treatment cycle was repeated every 21 days. Following 17 courses of treatment without adverse events, a complete response was observed. Furthermore, there was no recurrence within 6 months after the final course of therapy. This case indicates that UFT/LV + Bmab is suitable for the treatment of elderly patients with metastatic colorectal cancer.


2014 ◽  
Vol 15 (12) ◽  
pp. 955-956
Author(s):  
Julio Noda ◽  
Shannon Devlin ◽  
Gerald M. Mahon ◽  
Weigang Zhu

2019 ◽  
Vol 85 (11) ◽  
Author(s):  
Manuel Á. Gómez-Ríos ◽  
Rubén Casans-Francés ◽  
Alfredo Abad-Gurumeta

2020 ◽  
Vol Volume 13 ◽  
pp. 11849-11853
Author(s):  
Zhan Wang ◽  
Chen-Yang Ye ◽  
Wen-Li Zhou ◽  
Miao-Miao Wang ◽  
Wei-Ping Dai ◽  
...  

2019 ◽  
Vol 32 (5) ◽  
pp. 741-750 ◽  
Author(s):  
Carlo Basile ◽  
Francesco Gaetano Casino ◽  
Filippo Aucella

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